[PDF] Unravelling The Genetic Architecture Of Bicuspid Aortic Valve Related Aortopathy eBook

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Ehlers-Danlos Syndrome: A Multidisciplinary Approach

Author : J.W.G. Jacobs
Publisher : IOS Press
Page : 370 pages
File Size : 22,47 MB
Release : 2018-08-14
Category : Medical
ISBN : 1614998787

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Generalized hypermobility has been known since ancient times, and a clinical description of Ehlers-Danlos syndrome (EDS) is said to have first been recorded by Hippocrates in 400 BC. Hypermobility syndromes occur frequently, but the wide spectrum of possible symptoms, coupled with a relative lack of awareness and recognition, are the reason that they are frequently not recognized, or remain undiagnosed. This book is an international, multidisciplinary guide to hypermobility syndromes, and EDS in particular. It aims to create better awareness of hypermobility syndromes among health professionals, including medical specialists, and to be a guide to the management of such syndromes for patients and practitioners. It is intended for use in daily clinical practice rather than as a reference book for research or the latest developments, and has been written to be understandable for any healthcare worker or educated patient without compromise to the scientific content. The book is organized as follows: chapters on classifications and genetics are followed by chapters on individual types, organ (system) manifestations and complications, and finally ethics and therapeutic strategies, with an appendix on surgery and the precautions which should attend it. A special effort has been made to take account of the perspective of the patient; two of the editors have EDS. The book will be of interest to patients with hypermobility syndromes and their families, as well as to all those healthcare practitioners who may encounter such syndromes in the course of their work.

Surgical Management of Aortic Pathology

Author : Olaf H. Stanger
Publisher : Springer
Page : 1223 pages
File Size : 24,75 MB
Release : 2019-04-15
Category : Medical
ISBN : 370914874X

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This book follows the concept of perceiving the entire aorta as one functional organ assuming that all individual pathologies and local interventional procedures affect the up- and downstream segments with consequences for complications and disease progression. Thus any preventive or surgical strategy must recognize the aortic disease in its entirety. The book intends to cover the full spectrum of aortic pathologies, mechanisms and functional interplay. The latest available diagnostic tools and options for surgical treatment are presented by the foremost experts in their field in state-of-the-art reviews. The reader is provided with the most current and comprehensive insight into all fundamental and clinical aspects of aortic disease. All chapters are carefully complemented with figures and illustrations.

Multimodality Imaging Innovations In Adult Congenital Heart Disease

Author : Pastora Gallego
Publisher : Springer Nature
Page : 410 pages
File Size : 37,83 MB
Release : 2021-06-16
Category : Medical
ISBN : 3030619273

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This book focuses on congenital heart disease (CHD) and emerging imaging technologies. It covers all clinically relevant aspects of the fascinating new cardiac imaging technologies, including a comprehensive explanation of their basic principles, practical aspects of novel clinical applications, and detailed descriptions of specific uses in the broad spectrum of clinically important adult CHD. Innovations and emerging technologies for diagnosis and therapeutics, evaluation and treatment are continually evolving, and due to these advances in non-invasive diagnosis, there has been a significant improvement in the survival rates for CHD patient. Novel approaches to trans-catheter interventions and advances in echocardiography, MRI and CT imaging are being developed and incorporated into routine clinical practice, while emerging three-dimensional printing technologies are fundamentally affecting patient care, research, trainee education, and interactions between multidisciplinary teams, patients, and caregivers. In addition, translational technologies on the horizon promise to take this nascent field even further. Exploring the applicability of these emerging technologies in improving our understanding of complex congenital cardiac defect anatomy and physiology will provide new treatment options for this unique population. Written by experts in the field who are also involved in patient care, this book discusses the practical application of innovations in advanced multimodality imaging in the daily clinical routine and offers tips and tricks for beginners.

Aneurysms-Osteoarthritis Syndrome

Author : Denise van der Linde
Publisher : Elsevier
Page : 180 pages
File Size : 45,79 MB
Release : 2016-10-03
Category : Medical
ISBN : 0128027118

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Aneurysms-Osteoarthritis Syndrome: SMAD3 Gene Mutations is a first-of-its-kind compilation of the genetic discovery, research, and care associated with AOS. With the field of genetically triggered aortopathies growing, this important reference will compile the newest discoveries in this field, allowing cardiologists, cardio-thoracic surgeons, clinical geneticists, vascular surgeons, orthopedic surgeons, and researchers to gain the knowledge they need without having to gather the data from various sources. Coverage includes genotype and phenotype correlations, the functional role of SMAD3, and insights into the role of TGFbeta signaling in aortic disease. The book will increase knowledge about AOS, providing awareness and better patient care for this aggressive disease. Covers Aneurysms-Osteoarthritis Syndrome, from genetic discovery to patient care Contains clinical management guidance on optimal cardiovascular treatments and surgery Explains the autosomal dominant syndromes caused by mutations in the SMAD3 gene Identifies the key features of this syndrome, including arterial aneurysms and tortuosity, early onset arthritis, and mild craniofacial features

Biomarkers in Cardiovascular Disease

Author : Vijay Nambi
Publisher : Elsevier Health Sciences
Page : 400 pages
File Size : 45,5 MB
Release : 2018-11-27
Category : Medical
ISBN : 0323548369

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Get a quick, expert overview of the ways in which biomarkers can be used to assess and guide the management of cardiovascular disease in the clinical setting. This concise, clinically-focused resource by Dr. Vijay Nambi consolidates today’s available information on this rapidly changing topic into one convenient resource, making it an ideal, easy-to-digest reference for cardiology practitioners, fellows, and residents. Covers lab standards and statistical interpretation of biomarkers with a clinical focus. Discusses relevant conditions such as hypertension and diabetes as key markers of injury and prognosis. Includes current information on biomarkers to assess and guide the management of heart failure, acute coronary syndrome, chest pain, shortness of breath, and more. Concludes the book with a timely chapter on how biomarkers may guide cardiologists in the future.

The Eye in Pediatric Systemic Disease

Author : Alex V. Levin
Publisher : Springer
Page : 836 pages
File Size : 31,11 MB
Release : 2017-06-20
Category : Medical
ISBN : 3319183893

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​​This book is the first of its kind to describe ocular manifestations of systemic diseases in the pediatric population. Written and edited by experts in areas of pediatric ophthalmology and genetics, this new text covers a multitude of topics in a comprehensive and cataloged fashion. The Eye in Pediatric Systemic Disease is designed as an in-depth and up-to-date reference work that is heavily referenced, thus allowing the reader ready access to the international supporting literature. Everything from ocular manifestations of hematologic disease, child abuse, psychiatric diseases, renal disorders, and vitamin disorders are covered, allowing readers to know what to look for in the eyes of children with a given systemic disorder. The Eye in Pediatric Systemic Disease is written in language that is accessible to ophthalmologists and pediatricians, as well as allied health care professionals.

Emerging Topics and Controversies in Neonatology

Author : Elaine M. Boyle
Publisher :
Page : 597 pages
File Size : 30,53 MB
Release : 2020
Category : Neonatology
ISBN : 9783030288303

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This textbook addresses the themes that are at the forefront of neonatal clinical care and research, based on natural divisions in care during pregnancy, and postnatally by gestational age at birth. The book offers a unique approach, in that it proposes discussion of important general principles underpinning neonatal care that are not addressed in most general neonatology textbooks, such as ethical issues, counselling, effective training methods, quality and safety, among other subjects. These are fundamental aspects and challenges that need to be appreciated by senior clinicians. A chapter authored by parents describing their perspectives of neonatal intensive care is unique and will be highly educational, with the potential to influence the way in which individuals view and deliver neonatal care. The authors discuss common and important conditions, to promote adoption of sound evidenced based practice where this is available. However, where evidence is limited, as is the case in many areas of neonatal practice, the authors aim to encourage critical thinking and evidence appraisal, which are necessary skills for busy clinicians wishing to filter evidence to guide delivery of care. This text is suitable for senior trainees wishing to pursue a career in neonatal medicine, early career neonatologists and paediatricians with an interest in neonatology. It is also of interest to established neonatologists wishing to update their neonatal knowledge. The content is based on the RCPCH Level 3 curriculum, and addresses important topical and/or controversial aspects of neonatal care.

Hurst's the Heart, 13th Edition: Two Volume Set

Author : Valentin Fuster
Publisher : McGraw Hill Professional
Page : 2558 pages
File Size : 23,39 MB
Release : 2011-02-12
Category : Medical
ISBN : 007163648X

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The trusted landmark cardiology resource—thoroughly updated to reflect the latest clinical perspectives Includes DVD with image bank A Doody's Core Title ESSENTIAL PURCHASE for 2011! 5 STAR DOODY'S REVIEW! "This is an outstanding choice for those who strive for a firm foundation in cardiovascular medicine, as well as an up-to-date and user-friendly source that addresses every discipline in the field. The updates and enhancements to this edition have made the book easier to use."--Doody's Review Service Through thirteen editions, Hurst’s the Heart has always represented the cornerstone of current scholarship in the discipline. Cardiologists, cardiology fellows, and internists from across the globe have relied on its unmatched authority, breadth of coverage, and clinical relevance to help optimize patient outcomes. The thirteenth edition of Hurst’s the Heart continues this standard-setting tradition with 19 new chapters and 59 new authors, each of whom are internationally recognized as experts in their respective content areas. Featuring an enhanced, reader-friendly design, the new edition covers need-to-know clinical advances, as well as issues that are becoming increasingly vital to cardiologists worldwide. As in previous editions, you will find the most complete overview of cardiology topics available—plus a timely new focus on evidence-based medicine, health outcomes, and health quality. New Features 1548 full-color illustrations and 578 tables Companion DVD with image bank includes key figures and tables from the text The Cardiovascular Disease: Past, Present, and Future section includes a new chapter on assessing and improving quality of care in cardiovascular medicine The section on the scientific foundations of cardiovascular medicine has been thoroughly revised 2 new chapters in the section on the evaluation of the patient detail the process of effective diagnostic decision making based on technology, clinical trials, and practice guidelines A new chapter in the section on heart failure details cardiac transplantation The sections on primary heart disease include new chapters on topics such as preventive strategies for coronary artery disease and updated pharmacologic strategies for acute coronary syndromes The section on cardiopulmonary disease features new chapters on chronic cor pulmonale and sleep disorder breathing and its relationship to cardiovascular disease The section on valvular heart disease has four of the six chapter completely rewritten by new authors who are authorities in the field The final six sections feature new chapters on the environment and heart disease, surgical treatment of carotid and peripheral vascular disease and cost effective strategies in cardiology

A Brief History of Blood and Lymphatic Vessels

Author : Andreas Bikfalvi
Publisher : Springer
Page : 188 pages
File Size : 42,93 MB
Release : 2018-04-13
Category : Medical
ISBN : 3319743767

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This book provides a comprehensive account of vascular biology and pathology and its significance for health and disease. It systematically and chronologically explains how we came to our current understanding of the vasculature and it ́s function today, and describes in an entertaining way the diverse flaws and turns in science and medicine from the past. It thereby offers a complete and well-studied history on vascular biology and medicine. The book has an easy-to-read style and is written for students as well as scientists, physicians and lecturers in the field of biomedicine, human physiology, cardiology and hematology.