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Up-to-Date Details on Using Ultrasound Imaging to Help Diagnose Various DiseasesDue to improvements in image quality and the reduced cost of advanced features, ultrasound imaging is playing a greater role in the diagnosis and image-guided intervention of a wide range of diseases. Ultrasound Imaging and Therapy highlights the latest advances in usin
This book highlights advances and prospects of a highly versatile and dynamic research field: Therapeutic ultrasound. Leading experts in the field describe a wide range of topics related to the development of therapeutic ultrasound (i.e., high intensity focused ultrasound, microbubble-assisted ultrasound drug delivery, low intensity pulsed ultrasound, ultrasound-sensitive nanocarriers), ranging from the biophysical concepts (i.e., tissue ablation, drug and gene delivery, neuromodulation) to therapeutic applications (i.e., chemotherapy, sonodynamic therapy, sonothrombolysis, immunotherapy, lithotripsy, vaccination). This book is an indispensable source of information for students, researchers and clinicians dealing with non-invasive image-guided ultrasound-based therapeutic interventions in the fields of oncology, neurology, cardiology and nephrology.
This groundbreaking resource offers you exclusive coverage of the latest techniques in diagnostic and therapeutic 3-D ultrasound imaging instrumentation and techniques. Providing a solid overview of potential applications in clinical practice, you find need-to-know details on major diseases, including vascular diseases, breast cancer, cardiac abnormalities and prostate cancer.
Diagnostic Ultrasound Imaging provides a unified description of the physical principles of ultrasound imaging, signal processing, systems and measurements. This comprehensive reference is a core resource for both graduate students and engineers in medical ultrasound research and design. With continuing rapid technological development of ultrasound in medical diagnosis, it is a critical subject for biomedical engineers, clinical and healthcare engineers and practitioners, medical physicists, and related professionals in the fields of signal and image processing. The book contains 17 new and updated chapters covering the fundamentals and latest advances in the area, and includes four appendices, 450 figures (60 available in color on the companion website), and almost 1,500 references. In addition to the continual influx of readers entering the field of ultrasound worldwide who need the broad grounding in the core technologies of ultrasound, this book provides those already working in these areas with clear and comprehensive expositions of these key new topics as well as introductions to state-of-the-art innovations in this field. Enables practicing engineers, students and clinical professionals to understand the essential physics and signal processing techniques behind modern imaging systems as well as introducing the latest developments that will shape medical ultrasound in the future Suitable for both newcomers and experienced readers, the practical, progressively organized applied approach is supported by hands-on MATLAB® code and worked examples that enable readers to understand the principles underlying diagnostic and therapeutic ultrasound Covers the new important developments in the use of medical ultrasound: elastography and high-intensity therapeutic ultrasound. Many new developments are comprehensively reviewed and explained, including aberration correction, acoustic measurements, acoustic radiation force imaging, alternate imaging architectures, bioeffects: diagnostic to therapeutic, Fourier transform imaging, multimode imaging, plane wave compounding, research platforms, synthetic aperture, vector Doppler, transient shear wave elastography, ultrafast imaging and Doppler, functional ultrasound and viscoelastic models
With contributions by internationally re-knowned authorities and experts in the field of ultrasonic imaging, this book provides comprehensive reviews on basic physical principles and applications of emerging and rapidly developing therapeutic techniques.In specific, reviews of mechanisms for bioeffects of ultrasound relevant to therapeutic applications, high intensity focused ultrasound and its application in surgery, ultrasound assisted target drug and gene delivery, as well as transdermal drug delivery are discussed.The book will be a useful reference source for graduate students, academics and researchers.
Ultrasound has been widely used in diagnostic imaging for a long time. In the past 10 years, image-guided focused ultrasound therapy has seen rapid growth, in biomedical science and engineering, and in clinical medicine. The purpose of this book is to bring internationally renowned authorities and experts in this field together to provide up-to-date and comprehensive reviews of basic physics, biomedical engineering, and clinical applications of focused ultrasound therapy in a widely accessible fashion. Focusing on applications in cancer treatment, this book covers basic principles, practical aspects, and clinical applications of focused ultrasound therapy. It reviews the medical physics and bio-effects of focused ultrasound beams on living tissues, dosimetric methods and measurements, transducer engineering, image guidance and monitoring (including magnetic resonance imaging -- MRI -- and ultrasound), treatment delivery systems, and clinical applications. The book also gives practical guidelines on patient setup, target localisation, treatment planning and image-guided procedures for the treatment in various sites, including the prostate, liver, pancreas, breast, kidney, uterus, bone, and brain. The book discusses major challenges for the use of focused ultrasound energy on living tissues and explores the cellular and physiological responses that can be employed in the fight against cancer from biological, physics and engineering perspectives. It also highlights recent advances, including the treatment of solid tumours using image-guided drug delivery, and the exploitation of microbubbles, nanoparticles, and other cutting-edge techniques. Readers who are interested in learning more about the technique and the clinical applications described in each chapter can find more information in the comprehensive bibliographies provided. This book is suitable for anyone involved in, or looking to become involved in, the research and clinical applications of focused ultrasound therapy, including medical professionals, physicists, biomedical engineers, graduate students and others working in this multidisciplinary field. It offers a balanced and critical assessment of state-of-the-art technologies, major challenges, and an outlook on the future of focused ultrasound therapy. It presents a thorough introduction for those new to the field while providing helpful, up-to-date information and guidelines for readers already using this therapy in clinical and pre-clinical settings. Key Features: Brings together a wide range of world-leading experts in this new field, presenting the latest clinical outcomes of using focused ultrasound for the treatment of benign and malignant diseases Covers the fundamental physics of focused ultrasound therapy and ultrasound-mediated drug delivery, including chapters on the mechanism of sonoporation, microbubble and ultrasound interaction, and their potential clinical applications Introduces clinical guidelines for focused ultrasound therapy, including indications and contraindications, treatment goals, the selection of patients, clinical observation during treatment procedure and follow-up, and characteristics of image changes after treatment
Diagnostic Ultrasound Imaging provides a comprehensive introduction to and a state-of-the-art review of the essential science and signal processing principles of diagnostic ultrasound. The progressive organization of the material serves beginners in medical ultrasound science and graduate students as well as design engineers, medical physicists, researchers, clinical collaborators, and the curious. This it the most comprehensive and extensive work available on the core science and workings of advanced digital imaging systems, exploring the subject in a unified, consistent and interrelated manner. From its antecedents to the modern day use and prospects for the future, this it the most up-to-date text on the subject. Diagnostic Ultrasound Imaging provides in-depth overviews on the following major aspects of diagnostic ultrasound: absorption in tissues; acoustical and electrical measurements; beamforming, focusing, and imaging; bioeffects and ultrasound safety; digital imaging systems and terminology; Doppler and Doppler imaging; nonlinear propagation, beams and harmonic imaging; scattering and propagation through realistic tissues; and tissue characterization. Based on the author's over thirty-five years of experience in developing laboratory methodology and standards and conducting research in ultrasound. Conveys the fundamentals of diagnostic ultrasound as well as state-of-the-art reviews of major topics from a historical perspective. Matlab MATLAB problems and examples included. MATLAB problems and examples included
With contributions by internationally re-knowned authorities and experts in the field of ultrasonic imaging, this book provides comprehensive reviews on basic physical principles and applications of emerging and rapidly developing therapeutic techniques.In specific, reviews of mechanisms for bioeffects of ultrasound relevant to therapeutic applications, high intensity focused ultrasound and its application in surgery, ultrasound assisted target drug and gene delivery, as well as transdermal drug delivery are discussed.The book will be a useful reference source for graduate students, academics and researchers.