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Tumors of the Brain and Spine focuses primarily on approaches to the treatment of benign, primary low-grade to high-grade, and metastatic tumors in the brain and spine, as practiced by surgeons and clinicians at the University of Texas M. D. Anderson Cancer Center. The book is written mainly for the primary care oncologist, general neurologist, and general neurosurgeon. Discussion of treatment coverage focuses on neurosurgery, chemotherapy, and radiation therapy, singly and in combination. Also included are chapters on symptom management, molecular genetics and neuropathology of intracranial tumors, leptomeningeal dissemination of systemic cancer, epidemiology of brain tumors, and innovative treatment strategies.
Epidemiology of Brain and Spinal Tumors provides a single volume resource on imaging methods and neuroepidemiology of both brain and spinal tumors. The book covers a variety of imaging techniques, including computed tomography (CT), MRI, positron emission tomography (PET), and other laboratory tests used in diagnosis and treatment. Detailed epidemiology, various imaging methods, and clinical considerations of tumors of the CNS make this an ideal reference for users who will also find diverse information about structures and functions, cytology, epidemiology (including molecular epidemiology), diagnosis and treatment. This book is appropriate for neuroscience researchers, medical professionals and anyone interested in a complete guide to visualizing and understanding CNS tumors. Provides the most up-to-date information surrounding the epidemiology, biology and imaging techniques for brain and spinal tumors, including CT, MRI, PET, and others Includes full color figures, photos, tables, graphs and radioimaging Contains information that will be valuable to anyone interested in the field of neurooncology and the treatment of patients with brain and spinal tumors Serves as a source of background information for basic scientists and pharmaceutical researchers who have an interest in imaging and treatment
Atlas of Brain and Spine Oncology Imaging presents a comprehensive visual review of pathologic disease variations of cancers of the brain and spine through extensive radiologic images. The focus of the book is on algorithmic strategies for identifying neoplastic pathologies commonly found in brain and spinal tumors through a visual representation of the variety of appearances that each neoplasm takes, within both benign and malignant manifestations. With contributions from radiologists on staff at a National Cancer Institute-designated comprehensive cancer center, who draw from an extensive collection of diagnostic images across all imaging modalities, this book will be valuable to practicing radiologists, radiation oncologists, surgeons and other practitioners involved in the diagnosis and treatment of brain and spinal neoplasms in all patient populations.
Author : Lee Roy Morgan Publisher : BoD – Books on Demand Page : 278 pages File Size : 25,7 MB Release : 2020-01-29 Category : Medical ISBN : 1789841577
Numerous new concepts and procedures are reviewed and discussed in this book and allude to the transport of drugs to the brain. New radiation concepts are also presented, plus management of toxicities associated with both treatment modalities. It is the goal of this book to provide information and data that will be useful for both researchers and practitioners to develop new approaches for the management of CNS malignancies.
This book aims to gather the current knowledge regarding different aspects of brain and spinal cord tumors in order to more efficiently help the patients. Brain tumors comprise about 5–9% of all human neoplasms; and the central nervous system (CNS) neoplasms are ranked among the most prevalent neoplasms of childhood as well. The more we know about the nature and characteristic of brain and spinal cord tumors, the more precise decision could be made for each patient, in order to reach the best outcome. While surgical resection, chemotherapy, and radiotherapy have been considered as the standards of care for benign and/or malignant CNS tumors since a long time ago, new therapeutic approaches such as immunotherapy have been recently proposed to be considered for treatment of CNS tumors, especially as in some cases, the tumors might be inoperable or the patient may not benefit from other treatment modalities after several recurrences. The second volume of the book focuses on clinical aspects of these tumors. Accordingly, the most important brain and spinal cord tumors are specifically discussed in each chapter based on a rational outlining for all chapter in this volume: Background and epidemiology, genetics, immunology and molecular biology, histopathology and morphology, imaging and radiologic features, clinical manifestations, therapeutic approaches, surgical intervention, chemotherapy and radiotherapy, new therapeutic modalities, follow-up, and prognosis. The chapters of this volume discuss the following pathologies of brain and spinal cord tumors: malignant glioma, benign glioma, meningiomas and other meningeal tumors, ependymomas, medulloblastomas, pineal tumors, choroid plexus and ventricular tumors, neuroectodermal tumors of CNS, neuroepithelial tumors of CNS, pituitary gland tumors, craniopharyngioma, schwannomas and nerve-sheet tumors, hemangioblastomas and other vascular originating tumors, brain and spinal tumors of embryonic origin, germ line cell tumors, malignant bone or cartilage-originating tumors of brain and spine, benign bone or cartilage-originating tumors of brain and spine, brain tumors affecting the orbit globe and orbit tumors affecting the brain, CNS lymphomas, metastatic lesions of the brain and spine, malignant spinal tumors, benign spinal tumors, brain and/or spinal cord tumors accompanied with other diseases or syndromes, psychological and psychiatric aspects of brain and spinal cord tumors, a brief explanation on surgical approaches for treatment of different brain tumors. This volume of book is useful for physicians of different specialties, mainly neurosurgeons, neurologists, neuropathologists, and neuroradiologists.
This second edition comes at a time of a paradigm shift in understanding of the molecular pathology and neuroscience of brain and spinal tumors of childhood and their mechanisms of growth within the developing brain. Excellent collaborative translational networks of researchers are starting to drive change in clinical practise through the need to test many ideas in trials and scientific initiatives. This text reflects the growing concern to understand the impact of the tumour and its treatment upon the full functioning of the child’s developing brain and to integrate the judgments of the risks of acquiring brain damage with the risk of death and the consequences for the quality of life for those who survive. Information on the principles of treatment has been thoroughly updated. A chapter also records the extraordinary work done by advocates. All medical and allied professionals involved in any aspect of the clinical care of these patients will find this book an invaluable resource.
Tumors of the Brain and Spine focuses primarily on approaches to the treatment of benign, primary low-grade to high-grade, and metastatic tumors in the brain and spine, as practiced by surgeons and clinicians at the University of Texas M. D. Anderson Cancer Center. The book is written mainly for the primary care oncologist, general neurologist, and general neurosurgeon. Discussion of treatment coverage focuses on neurosurgery, chemotherapy, and radiation therapy, singly and in combination. Also included are chapters on symptom management, molecular genetics and neuropathology of intracranial tumors, leptomeningeal dissemination of systemic cancer, epidemiology of brain tumors, and innovative treatment strategies.
Author : M.A. Hayat Publisher : Springer Science & Business Media Page : 381 pages File Size : 22,83 MB Release : 2011-09-15 Category : Medical ISBN : 9400717067
This volume mainly contains information on the diagnosis, therapy, and prognosis of brain tumors. Insights on the understanding of molecular pathways involved in tumor biology are explained, which should lead to the development of effective drugs. Information on pathways (e.g., hedgehog) facilitates targeted therapies in cancer. Tumor models are also presented, which utilize expression data, pathway sensitivity, and genetic abnormalities, representing targets in cancer. For example, rat model of malignant brain tumors using implantation of doxorubicin with drug eluting beads for delivery is explained. The future of pathway-driven therapies for tumors is summarized. The importance of personalizing cancer care is emphasized. The need for supportive measures for survivors of brain cancer is pointed out, so is the quality of life monitoring. The need of rehabilitation therapy for patients with primary and metastatic brain tumors is also emphasized. Role of MicroRNA in distinguishing primary tumors from metastatic primary tumors is discussed. Advantages and limitations of chemotherapy (e.g., temozolomide and doxorubicin) are discussed. The complexity of tumor to tumor transfer is explained; examples discussed are: brain metastases from breast cancer and brain metastases fro non-small cell lung carcinoma. Identification and characterization of biomarkers, including those for metastatic brain tumors, are presented. Genomic analysis for identifying clinically relevant subtypes of glioblastoma is included. A large number of imaging modalities are detailed to study progression and invasion of gliomas