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Towards the Eradication of Helicobacter pylori Infection - Rapid Diagnosis and Precision Treatment

Author : Liang Wang
Publisher : BoD – Books on Demand
Page : 166 pages
File Size : 28,85 MB
Release : 2024-05-15
Category : Medical
ISBN : 0854664467

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"Towards the Eradication of Helicobacter pylori Infection - Rapid Diagnosis and Precision Treatment" book is a comprehensive guide to combating one of the most persistent challenges in global public health. In this volume, experts from various disciplines have joined forces to present the latest research, clinical insights, and practical applications for diagnosing and treating H. pylori infection. The chapters present in this volume cover diagnostic modalities in detecting H. pylori infection, from rapid noninvasive techniques for detecting antibiotic resistance to the utility of linked color imaging in endoscopic diagnosis. The book also presents innovative treatment strategies, including the role of cytokines in inflammation, the impact of antibiotic resistance patterns, and the potential of immunotherapeutic approaches. Healthcare professionals, researchers, and students should benefit from this volume in developing the knowledge and tools necessary to combat and eradicate H. pylori infection effectively.

The Pathology, Diagnosis and Treatment of Helicobacter Pylori Infection

Author :
Publisher :
Page : pages
File Size : 42,70 MB
Release : 2001
Category :
ISBN :

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(Uncorrected OCR) Abstract of thesis entitled The Pathology, Diagnosis and Treatment of Helicobacter pylori Infection Submitted by Wong Wai Man, Raymond for the degree of Doctor of Medicine at The University of Hong Kong in July 2001 The aims of this thesis were 1) to study Helicobacter pylori (H. pylori) related mucosal pathology; 2) to evaluate the best diagnostic test for H. pylori; and 3) to test the efficacy of 3 different therapies for H. pylori infection. Pseudopyloric metaplasia represents a metaplasia of the pyloric glands and is closely associated with hyperplasia of the mucous neck cells (MNC). Both MNC hyperplasia and pseudopyloric metaplasia were associated with H. pylori gastritis. This lineage expressed TFF2, MUC6, PSTI and lysozyme. Ulcerative associated cell lineage was seen to arise from pre-existing crypts in areas of intestinal metaplasia, and plays no part in the histogenesis of pseudopyloric metaplasia. Intestinal metaplasia, which is a H. pylori related pre-malignant lesion of the gastric mucosa, showed evidence of cell cycle de- regulation in the goblet and Paneth cell lineages but not in endocrine cell lineage, which have considerable implications for the biology of intestinal metaplasia. Helicobacter pylori infection can be diagnosed by invasive and noninvasive tests. Five invasive tests and one non- invasive test were evaluated. For routine clinical use, histology, rapid urease test and 13C_ Urea breath test (13C_ UBT) had an accuracy of 100%, 99.7%and 94.5% respectively. For research purposes, the accuracy of two positives out of three diagnostic tests was equally reliable. A new rapid urease test, the PyloriTek test was evaluated for the diagnosis of H. pylori infection before and after eradication therapy. It is highly accurate and one biopsy from the antrum was reliable. A simplified 75gm 13C_ UBT was evaluated in Chinese population. The optimal delta-value and optimal measurement interval for UBT were 5%0 and 30 minutes respectively.

The Helicobacter pylori Handbook

Author : RV Heatley
Publisher : Wiley-Blackwell
Page : 72 pages
File Size : 11,73 MB
Release : 1999-02-02
Category : Medical
ISBN : 9780632051762

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The link between Helicobacter pylori infection and ulcer disease has been one of the most significant discoveries in the past decade. The role of this organism in the development of non-ulcer dyspepsia, gastric cancer, lymphoma and even heart disease is also attracting much interest. For those whose speciality lies outside of gastroenterology it is extremely difficult to keep abreast of this rapidly moving area. In the last year alone (1998), 1,300 works on Helicobacter pylori have been published. With this in mind, The Helicobacter pylori Handbook/b> provides a concise and up-to-date review of H.pylori infection, with updated sections on its diagnosis and treatment, and the position of H.pylori eradication in the management of gastrointestinal disorders.

Precision Medicine and Human Health

Author : Farzana Mahdi
Publisher : Bentham Science Publishers
Page : 561 pages
File Size : 28,48 MB
Release : 2024-06-03
Category : Medical
ISBN : 9815223593

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Precision Medicine and Human Health covers several aspects of precision medicine in 20 edited reviews by researchers and healthcare professionals. The breadth of information provided by the contributors aims to familiarize readers with basic and applied research in personalized therapy. Starting with an overview of the subject and its relationship with epigenetics, the book progresses into advanced topics that explain its wider applications. The use of precision medicine in treating different diseases such as protein misfolding disorders, gut ulcers and their effect on the gut microbiome, cancer treatment (for hepatocellular carcinoma, breast cancer, and oral cancer), fibromyalgia, high altitude sickness, and multiple sclerosis is explained. The book also covers modern therapeutic techniques to administer personalized therapy, including epithelial-mesenchymal therapy (EMT), circadian clock modulation, and artificial intelligence and phytoconstituents. The next chapters cover advanced technologies that are crucial to precision medicine, such as nanomaterials and advanced drug delivery systems. A concluding chapter on the therapeutic use of tannins in precision medicine rounds up the contents. Key Features: - Features 20 focused chapters contributed by scientific experts - Introduces readers to basic concepts in precision medicine - Covers the application of precision medicine in treating different diseases - Showcases several techniques used in experimental and clinical precision therapy - Explains modern technologies in precision medicine - Caters to a wide readership with introductions, structured headings, and references This is an informative reference for healthcare professionals in clinics and hospitals and any scholar who wants to learn about basic and applied knowledge in precision medicine.

Gastritis

Author : Bruna Maria Roesler
Publisher : BoD – Books on Demand
Page : 127 pages
File Size : 32,46 MB
Release : 2019-12-18
Category : Medical
ISBN : 1789846641

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The isolation and identification of Helicobacter pylori as the cause of gastrointestinal diseases had major implications for public health and led to curative treatments that reduced suffering from many acute and chronic conditions. Although alternative therapies have been used to improve eradication, current treatments still rely on a combination of antimicrobial agents often associated with antisecretory agents, such as proton pump inhibitors. In this book there is a comprehensive overview by contributors on H. pylori infection in diverse areas, including a general overview of H. pylori infection, and discussions about the principal therapeutic regimens of bacterium eradication, considering antimicrobial resistance. Also, certain aspects of autoimmune gastritis, an important condition that has been related to microorganism infection, is also considered. H. pylori is clearly a very interesting bacterium and great studies and discussions about all its aspects are welcomed by the medical and scientific communities.

Case Studies in Public Health

Author : Theodore H. Tulchinsky
Publisher : Academic Press
Page : 605 pages
File Size : 18,22 MB
Release : 2018-03-12
Category : Technology & Engineering
ISBN : 0128045868

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Case Studies in Public Health contains selected case studies of some of the most important and influential moments in medicine and epidemiology. The cases chosen for this collection represent a wide array of public health issues that go into the makeup of what can be termed the New Public Health (NPH), which includes traditional public health, such as sanitation, hygiene and infectious disease control, but widens its perspective to include the organization, financing and quality of health care services in a much broader sense. Each case study is presented in a systematic fashion to facilitate learning, with the case, background, current relevance, economic issues, ethical issues, conclusions, recommendation and references discussed for each case. The book is a valuable resource for advanced students and researchers with specialized knowledge who need further information on the general background and history of public health and important scientific discoveries within the field. It is an ideal resource for students in public health, epidemiology, medicine, anthropology, and sociology, and for those interested in how to apply lessons from the past to present and future research. Explores the history of public health through important scientific events and flashpoints Presents case studies in a clear, direct style that is easy to follow Uses a systematic approach to help learn lessons from the past and apply them to the present

Progress in China Epidemiology

Author : Dong-Qing Ye
Publisher : Springer Nature
Page : 478 pages
File Size : 44,22 MB
Release : 2023-01-06
Category : Medical
ISBN : 9811921997

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This book is intended to show the great achievements and valuable experience of Chinese public health practices and epidemiological theories and methods. It is conducive to expanding medical workers’ practical ability of disease prevention and control, and to bridging the gap between clinical medicine and public health. In part 1, it introduces the progress in epidemiology of 10 infectious diseases. In part 2, it covers 11 non-communicable diseases. The research method and prediction modelling and public health ethics are discussed in the 11 chapters of part 3. The contributors include epidemiologists and public health experts, as well as more clinicians, mathematicians, sociologists, philosophers (ethicists), bioinformatics and so on. Among them, there are not only professors from universities, but also researchers from scientific research institutes, and experts in the front line of disease prevention and control.

Geriatric Gastroenterology

Author : C. S. Pitchumoni
Publisher : Springer Science & Business Media
Page : 660 pages
File Size : 38,96 MB
Release : 2012-07-26
Category : Medical
ISBN : 1441916237

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As aging trends in the United States and Europe in particular are strongly suggestive of increasingly older society, it would be prudent for health care providers to better prepare for such changes. By including physiology, disease, nutrition, pharmacology, pathology, radiology and other relevant associated topics, Geriatric Gastroenterology fills the void in the literature for a volume devoted specifically to gastrointestinal illness in the elderly. This unique volume includes provision of training for current and future generations of physicians to deal with the health problems of older adults. It will also serve as a comprehensive guide to practicing physicians for ease of reference. Relevant to the geriatric age group, the volume covers epidemiology, physiology of aging, gastrointestinal physiology, pharmacology, radiology, pathology, motility disorders, luminal disorders, hepato-biliary disease, systemic manifestations, neoplastic disorders, gastrointestinal bleeding, cancer and medication related interactions and adverse events, all extremely common in older adults; these are often hard to evaluate and judge, especially considering the complex aging physiology. All have become important components of modern medicine. Special emphasis is be given to nutrition and related disorders. Capsule endoscopy and its utility in the geriatric population is also covered. Presented in simple, easy to read style, the volume includes numerous tables, figures and key points enabling ease of understanding. Chapters on imaging and pathology are profusely illustrated. All chapters are written by specialists and include up to date scientific information. Geriatric Gastroenterology is of great utility to residents in internal medicine, fellows in gastroenterology and geriatric medicine as well as gastroenterologists, geriatricians and practicing physicians including primary care physicians caring for older adults.

Guidelines on Hepatitis B and C Testing

Author : World Health Organization
Publisher : World Health Organization
Page : 0 pages
File Size : 34,15 MB
Release : 2017
Category : Medical
ISBN : 9789241549981

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Testing and diagnosis of hepatitis B (HBV) and C (HCV) infection is the gateway for access to both prevention and treatment services, and is a crucial component of an effective response to the hepatitis epidemic. Early identification of persons with chronic HBV or HCV infection enables them to receive the necessary care and treatment to prevent or delay progression of liver disease. Testing also provides an opportunity to link people to interventions to reduce transmission, through counselling on risk behaviors and provision of prevention commodities (such as sterile needles and syringes) and hepatitis B vaccination. These are the first WHO guidelines on testing for chronic HBV and HCV infection and complement published guidance by WHO on the prevention, care and treatment of chronic hepatitis C and hepatitis B infection. These guidelines outline the public health approach to strengthening and expanding current testing practices for HBV and HCV, and are intended for use across age groups and populations.