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Thyroid and Heart Failure

Author : Giorgio Iervasi
Publisher : Springer Science & Business Media
Page : 264 pages
File Size : 30,32 MB
Release : 2009-08-29
Category : Medical
ISBN : 8847011434

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Both thyroid dysfunction and heart failure show a high prevalence in the adult population. Frequently, in clinical practice, a multidisciplinary approach is useful to optimize the management of patients with these conditions. Although there is no doubt regarding the close link between cardiovascular pathophysiology and thyroid homeostasis, our understanding of this association is far from being exhaustive. Thyroid hormone regulates the expression of cardiac-specific functional contractile and structural proteins and plays a pivotal role in modulating both diastolic and systolic function as well as peripheral vascular resistance. The close relationship between thyroid and heart dysfunction is strongly supported by recent evidence demonstrating that an altered thyroid profile is a negative prognostic predictor in patients with heart failure. The treatment of chronic heart failure, especially in advanced stages of the disease, continues to be an open and challenging field. The potential of novel thyroid hormone therapies that address the molecular biology of thyroid dysfunction and heart failure thus represents an attractive area of multidisciplinary scientific interest. This book is a readable, integrated, and highly up to date presentation of the clinical, pathophysiological, and basic science aspects of thyroid–heart failure interactions. It addresses a complex subject in an approach that targets a large audience of readers.

Thyroid and Heart

Author : Giorgio Iervasi
Publisher : Springer Nature
Page : 436 pages
File Size : 44,94 MB
Release : 2020-03-19
Category : Medical
ISBN : 3030368718

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In recent years, several scientific papers have highlighted the role of the thyroid system in cardioprotection, and several clinical studies – including multicenter studies – have identified the role of thyroid hormones (TH) in the development and progression of cardiovascular disease, making an update of TH and heart relationship both necessary and timely. This second edition of Thyroid and Heart failure provides a careful and updated review of the experimental, clinical and epidemiological results in the field of TH and heart failure, with a particular focus on the translational - bench to bedside - significance of the obtained results. It discusses topics such as the molecular, structural, functional, cellular and histological cardiac changes; the reversibility of these changes with TH replacement therapy; the systemic effects – kidney, hormonal pathways systems, brain, muscle, etc – of altered TH metabolism in HF, as well as the clinical and prognostic implications. The section devoted to the potential therapeutic treatments has been expanded. Thanks to its translational approach to this highly complex subject, the book will be of interest to a broad readership, including cardiologists, endocrinologists and internists.

70 Years of Levothyroxine

Author : George J. Kahaly
Publisher : Springer Nature
Page : 141 pages
File Size : 23,33 MB
Release : 2021-03-11
Category : Medical
ISBN : 3030632776

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This open access book presents the history, pharmacokinetics and pharmacodynamics of levothyroxine, discussing its role in the thyroid pathophysiology of patients of various ages and during pregnancy. It also describes the influence of levothyroxine on heart, bone and in cancer. When it was first synthesized in 1949, levothyroxine represented a significant advance in the treatment of hypothyroidism, providing a safe and effective treatment option for millions of hypothyroid patients around the globe. This synthetic form of thyroxine is now one of the most prescribed drugs in the world. Levothyroxine was first introduced by Merck KGaA,Darmstadt, Germany, in 1972, and since then the company has remained actively engaged in research on this mainstay of hypothyroidism treatment. This book is intended for healthcare professionals.

Cardiology Explained

Author : Euan A. Ashley
Publisher : Remedica
Page : 258 pages
File Size : 28,25 MB
Release : 2004
Category : Cardiology
ISBN : 1901346226

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One of the most time-consuming tasks in clinical medicine is seeking the opinions of specialist colleagues. There is a pressure not only to make referrals appropriate but also to summarize the case in the language of the specialist. This book explains basic physiologic and pathophysiologic mechanisms of cardiovascular disease in a straightforward manner, gives guidelines as to when referral is appropriate, and, uniquely, explains what the specialist is likely to do. It is ideal for any hospital doctor, generalist, or even senior medical student who may need a cardiology opinion, or for that ma.

Cardiac Effects of Hypothyroidism and Hyperthyroidism

Author : James M. Lowrance
Publisher : CreateSpace
Page : 44 pages
File Size : 45,84 MB
Release : 2012-01-29
Category : Health & Fitness
ISBN : 9781469996936

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This title is also a section found in the book titled: "Common Murmurs, Arrhythmias and Myopathies of the Heart" and is being made available for readers interested in heart conditions related to thyroid disease specifically. DESCRIPTION OF THIS TITLE: Thyroid disease is a major contributor to heart conditions of various types and can manifest as either hypothyroid or hyperthyroid disorders. This is why it is very important for both men and women (especially women), to be checked for abnormal thyroid hormone levels, beginning at age 35. A check for developing hypothyroidism or hyperthyroidism should also be done, at any point in life regardless of age, when symptoms of either condition appear to be developing. Catching and treating thyroid disorders at their earliest stages, can help to prevent associated heart conditions from also developing or from worsening if already present. When people become thyroid hormone imbalanced, this can also exacerbate an already existing cardiac condition, which also means that treatments determined to be needed, by a qualified medical doctor or doctors (plural in cases when both an endocrinologist and cardiologist are needed), require more diligence on the part of both patient and physician, in order to extend life-expectancy and to maintain a better quality of life. Within the chapters of this book, I address the types of heart conditions or cardiac effects that thyroid diseases can have on those who experience them. I also discuss the treatments in-general, that are administered to correct or to help control these potentially serious problems. It is my sincere hope that this resource helps to provide a worthy general educational resource for its readers. NOTE: This book is approximately 6,142 words in length. It is not intended as an extensive medical journal but rather contains all aspects of information on the subject that most laypersons would be seeking. CONTENTS: CHAPTER ONE Hypercholesterolemia from Underactive Thyroid Gland CHAPTER TWO Thyrotoxicity and Heart Arrhythmias CHAPTER THREE Hyperthyroid and Hypothyroid Cardiomyopathy CHAPTER FOUR PVCs and PACs from Thyroid Hormone Imbalance

Goiter

Author : N.K. Agrawal
Publisher : BoD – Books on Demand
Page : 146 pages
File Size : 23,52 MB
Release : 2020-04-08
Category : Medical
ISBN : 1789859638

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The thyroid gland is a commonly diseased endocrine organ of human body. The disorders affecting the thyroid gland are varied but are very much amenable to treatment. The enlargement of the thyroid is termed goiter. It can affect the whole gland or only part of it. The disease is perplexing but in-depth knowledge of the pathophysiology helps in elucidating causes and thereby treating the disease. In this book, the diffuse and nodular goiter has been addressed as well as the functional abnormalities of the gland and its implications on the body are discussed in various chapters. The relevant updated information is included. To address a few of these current issues and recent updated information, authors have put in a lot of effort to organize the book.

Amiodarone in Cardiac Arrhythmias

Author : Wilfrid Tord Simpson
Publisher : Royal Society of Medicine Press
Page : 84 pages
File Size : 34,60 MB
Release : 1979
Category : Medical
ISBN :

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Thyroid and Heart

Author :
Publisher :
Page : 429 pages
File Size : 22,29 MB
Release : 2020
Category : Heart
ISBN : 9783030368722

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In recent years, several scientific papers have highlighted the role of the thyroid system in cardioprotection, and several clinical studies - including multicenter studies - have identified the role of thyroid hormones (TH) in the development and progression of cardiovascular disease, making an update of TH and heart relationship both necessary and timely. This second edition of Thyroid and Heart failure provides a careful and updated review of the experimental, clinical and epidemiological results in the field of TH and heart failure, with a particular focus on the translational - bench to bedside - significance of the obtained results. It discusses topics such as the molecular, structural, functional, cellular and histological cardiac changes; the reversibility of these changes with TH replacement therapy; the systemic effects - kidney, hormonal pathways systems, brain, muscle, etc - of altered TH metabolism in HF, as well as the clinical and prognostic implications. The section devoted to the potential therapeutic treatments has been expanded. Thanks to its translational approach to this highly complex subject, the book will be of interest to a broad readership, including cardiologists, endocrinologists and internists. .

Anesthetic Pharmacology

Author : Alex S. Evers
Publisher : Cambridge University Press
Page : 2902 pages
File Size : 35,68 MB
Release : 2011-03-10
Category : Medical
ISBN : 1139497022

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In recent years our understanding of molecular mechanisms of drug action and interindividual variability in drug response has grown enormously. Meanwhile, the practice of anesthesiology has expanded to the preoperative environment and numerous locations outside the OR. Anesthetic Pharmacology: Basic Principles and Clinical Practice, 2nd edition, is an outstanding therapeutic resource in anesthesia and critical care: Section 1 introduces the principles of drug action, Section 2 presents the molecular, cellular and integrated physiology of the target organ/functional system and Section 3 reviews the pharmacology and toxicology of anesthetic drugs. The new Section 4, Therapeutics of Clinical Practice, provides integrated and comparative pharmacology and the practical application of drugs in daily clinical practice. Edited by three highly acclaimed academic anesthetic pharmacologists, with contributions from an international team of experts, and illustrated in full colour, this is a sophisticated, user-friendly resource for all practitioners providing care in the perioperative period.