[PDF] Theranostics Approaches To Gastric Cancer eBook

Author : Donald Maxmilian
Publisher : American Medical Publishers
Page : 0 pages
File Size : 26,42 MB
Release : 2023-09-26
Category : Medical
ISBN :

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The term theranostics is derived from the combination of two words, namely, therapeutics and diagnostics. It is a practical aspect of personalized medicine. It involves using a combination of one radioactive drug to identify (diagnose) and a second radioactive drug to provide therapy in order to treat a tumor. Gastric cancer, also known as stomach cancer, develops due to the formation of malignant cancer cells in the lining of the stomach. The factors such as age, diet, and stomach diseases result in the development of gastric cancer. Some of the common symptoms of this cancer include unexplained weight loss, severe abdominal pain, nausea and vomiting, difficulty in swallowing, etc. It can be diagnosed with the help of imaging tests such as CT or CAT scans, PET scans, MRI, or upper gastrointestinal endoscopy. Theranostics includes molecular targeting and nanotechnologies which are increasingly finding many applications in the treatment of gastric cancer. In this book, the various advancements in the field of theranostics as well as their application for the treatment of gastric cancer have been looked at in detail. For all readers who are interested in this area of study, the case studies included herein will serve as an excellent guide to develop a comprehensive understanding.

Author : Ganji Seeta Rama Raju
Publisher : Springer Nature
Page : 261 pages
File Size : 11,73 MB
Release : 2020-03-04
Category : Medical
ISBN : 9811520178

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This book highlights the importance of understanding gastric and colon cancer metabolism in guiding diagnosis and drug discovery. It summarizes the correlation between adiponectin and matrix metalloproteinase with colorectal cancer. The book also evaluates the divergent role of hypoxia-inducible factor 1 in colorectal cancer growth and metastasis. After discussing the role of genetic polymorphisms in alcohol metabolizing enzymes and EPHX1 with the onset of colorectal cancer, it reviews the molecular mechanisms of chemoresistance in gastric cancer and novel therapeutic strategies to reverse the chemoresistance of tumors. In addition, the book explores the theranostic role of nanoparticles and therapeutic potential of phytochemicals with regard to colorectal cancer. Given its scope, the book offers a valuable guide for oncologists, academic researchers, pharmaceuticals practitioners, and students who are involved in research and treatment of cancer.

Author :
Publisher :
Page : 261 pages
File Size : 21,7 MB
Release : 2020
Category : Colon (Anatomy)
ISBN : 9789811520181

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This book highlights the importance of understanding gastric and colon cancer metabolism in guiding diagnosis and drug discovery. It summarizes the correlation between adiponectin and matrix metalloproteinase with colorectal cancer. The book also evaluates the divergent role of hypoxia-inducible factor 1 in colorectal cancer growth and metastasis. After discussing the role of genetic polymorphisms in alcohol metabolizing enzymes and EPHX1 with the onset of colorectal cancer, it reviews the molecular mechanisms of chemoresistance in gastric cancer and novel therapeutic strategies to reverse the chemoresistance of tumors. In addition, the book explores the theranostic role of nanoparticles and therapeutic potential of phytochemicals with regard to colorectal cancer. Given its scope, the book offers a valuable guide for oncologists, academic researchers, pharmaceuticals practitioners, and students who are involved in research and treatment of cancer. --

Author : Vivian E. Strong
Publisher : Springer
Page : 331 pages
File Size : 34,49 MB
Release : 2015-06-10
Category : Medical
ISBN : 3319158260

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This volume provides the most comprehensive and complete resource available on all aspects of gastric cancer and it’s management. The book covers topics such as oncologic approaches to staging, treating, and following patients, filling a critical need for resource materials on these areas. As multidisciplinary care is an integral part of gastric cancer treatment, this text is unique in including a renowned group of expert authors from a variety of disciplines, including pathology, gastroenterology, medical oncology, surgery and clinical genetics. In addition, authors from an international pool of gastric cancer experts have covered the breadth of practice and understanding globally. Edited and organized by an expert from one of the most highly respected cancer institutions in the country, Gastric Cancer: Principles and Practice is an expert review of this field, serving as a valuable reference for physicians in training and in practice, as well as for researchers who are interested in the scope of issues and advances in this important malignancy.

Author : Ganji Purnachandra Nagaraju
Publisher : Springer Nature
Page : 259 pages
File Size : 45,35 MB
Release : 2020-10-01
Category : Medical
ISBN : 9811554714

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This book provides an up-to-date overview of gastrointestinal malignancies, including prevention, early detection, intervention, and life-extending therapeutics. It also assesses various biomarkers used for diagnostics, prognostics and prediction of response to chemoresistance. Further, it discusses the latest trends in the use of small-molecule targeted therapies and immunotherapies as single agents or combination with other treatments. Since resistance to radiation and chemotherapy contribute to the high recurrence and poor survival rates, improving the outcome for GI malignancies is dependent on the introduction of new biomarkers and therapeutic agents. Lastly, the book systematically investigates novel theranostics approaches using nanotechnology for the detection, diagnosis, and personalized treatment of GI malignancies.

Author : Giovanni de Manzoni
Publisher : Springer Nature
Page : 276 pages
File Size : 50,18 MB
Release : 2021-10-15
Category : Medical
ISBN : 3030731588

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Twenty-five years ago, a monograph on gastric cancer was published by the Italian Society of Surgery: that book is recognized as a milestone in the management of these tumors in Italy. Oncological and surgical knowledge in the field of gastric cancer have changed dramatically over the last 25 years. The aim of this book is to offer an essential update on current diagnostic approaches and optimal treatment strategies. It gives comprehensive information on gastric cancer not neglecting the basic sciences, which can shed light on the carcinogenesis mechanisms involved in this pathology. The principles of tailored and multimodal treatment are examined according to the latest guidelines with the aim of providing a valuable synopsis for clinicians. The book not only reviews what has changed in the field of gastric cancer over the past quarter century but also offers the reader a glimpse of the future by describing the ongoing surgical and oncological trials which focus on new treatment frontiers such as immunotherapy and target therapy. It also seeks to incorporate the latest discoveries based on molecular classifications. Further, the book reflects the findings and experiences of Italian experts belonging to the GIRCG (Italian Research Group for Gastric Cancer) and will offer an excellent guide for oncological surgeons in their daily practice of caring for patients affected by gastric cancer.

Author : Daxiang Cui
Publisher : Springer
Page : 361 pages
File Size : 32,45 MB
Release : 2017-06-21
Category : Medical
ISBN : 9402409513

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The book explores recent developments in the application of nanotechnology in the early detection of gastric cancer. It discusses various aspects, such as screening for gastric cancer-associated biomarkers; establishing new ultrasensitive detection methods based on nanoparticle labeling and nanoeffects; developing a new generation of nanodevices for high-throughput examination of serum and breath biomarkers; developing multifunctional nanoprobes for targeted imaging and simultaneous therapy of gastric cancer; evaluating the biosafety of multifunctional nanoprobes; and the establishment of a pre-warning and early diagnosis system. It also presents clinical applications and prospects. The book provides a valuable reference for researchers in nanomedicine and clinicians involved in gastric cancer and radiology.

Author : Lin Chen
Publisher :
Page : 0 pages
File Size : 20,59 MB
Release : 2020
Category :
ISBN :

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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Author : Joao Conde
Publisher : Elsevier
Page : 608 pages
File Size : 47,59 MB
Release : 2018-06-27
Category : Science
ISBN : 0128133406

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Handbook of Nanomaterials for Cancer Theranostics focuses on recent developments in advanced theranostic nanomedicines from a chemical and biological perspective where the advantages of theranostics are achieved by combining multiple components. The authors explore the pros and cons of theranostic nanomaterials developed in cancer research in the last 15 years, with the different strategies compared and scrutinized. In addition, the book explores how nanomaterials may overcome the regulatory hurdles facing theranostic nanomedicines. This is an important research reference for postgraduates and researchers in nanomedicine and cancer research who want to learn more on how nanomaterials can help create more effective cancer treatments. Highlights the development of smart theranostic nanomaterials to tackle biomedical problems in cancer therapy and diagnostics Explores the regulatory hurdles facing theranostic nanomedicine Discusses how the use of nanomaterials can help create more effective cancer treatments