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Placebo and Pain

Author : Bettina K. Doering
Publisher : Elsevier Inc. Chapters
Page : 28 pages
File Size : 37,15 MB
Release : 2013-08-28
Category : Medical
ISBN : 0128064323

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Nocebo effects are extremely common in clinical practice, and they are induced by a patient’s negative expectancies about a treatment outcome. They may occur after an inert treatment, or after the administration of a pharmacologically active substance, and modulate the treatment outcome. Nocebo effects in clinical practice manifest themselves in the deterioration of a pre-existing symptomatology or in the development of new symptoms that are often considered as nonspecific side effects and are ascribed to the medical regimen. Nocebo responses can be induced by components of the therapeutic encounter, e.g. the communication of the diagnosis, information about the treatment, the disclosure of risks and benefits of the treatment, or the verbal interaction during the treatment. This chapter reviews empirical evidence from clinical populations that documents nocebo effects in the different stages of the therapeutic process. Based on this review, it suggests strategies for the minimization of nocebo effects in clinical practice.

Pain

Author : Alaa Abd-Elsayed
Publisher : Springer
Page : 1334 pages
File Size : 38,40 MB
Release : 2019-05-10
Category : Medical
ISBN : 3319991248

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This concise but comprehensive guide covers common procedures in pain management necessary for daily practice, and includes topics on international pain medicine curricula, for example, the American Board of Anesthesiology, World Institute of Pain/Fellow of Interventional Pain Practice, and American Board of Pain Medicine. Treatments for pain are discussed, including nerve blocks (head, neck, back, pelvis and lower extremity). Chapters have a consistent format including high yield points for exams, and questions in the form of case studies. Pain: A Review Guide is aimed at trainees in pain medicine all over the world. This book will also be beneficial to all practitioners who practice pain.

Oxford Textbook of Osteoarthritis and Crystal Arthropathy, Third Edition

Author : Michael Doherty
Publisher : Oxford University Press
Page : 529 pages
File Size : 17,11 MB
Release : 2016-10-06
Category : Medical
ISBN : 0199668841

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A trustworthy clinical companion, the textbook offers best practice and management strategies for these common joint diseases. Formerly published as Osteoarthritis, the extensively revised third edition of the Oxford Textbook of Osteoarthritis and Crystal Arthropathy provides up-to-date and evidence-based guidance on how to assess, diagnose, and manage patients. A prestigious and international author team ensure information is expert and relevant-this is a practical tool for clinicians managing people with osteoarthritis, gout, and other crystal-associated arthritis. Confidently consider and chose the right blend of treatment for your patient, whether physical, pharmacological, surgical, or supportive. The Oxford Textbook of Osteoarthritis and Crystal Arthropathy provides full coverage of joint failure, and includes detailed sections on epidemiology, risk factors, clinical assessment, and investigations. This edition also now includes new sections on gout and other crystal arthropathies. Clinically relevant and easily understandable overviews of basic science, including pathology and pain physiology, along with critical appraisal of current guidelines, make this a highly valuable resource. Significant coverage is also given to patient education and the involvement of the patient in management planning. Also highly illustrated, the textbook is a strong reference tool with summary boxes and key points at the end of chapters making it easy to find information quickly and help you deliver the optimum patient outcome. The textbook equips rheumatologists and musculoskeletal health professionals with the knowledge to provide best possible patient care.

Placebo and Nocebo Effects in Psychiatry and Beyond

Author : Paul Enck
Publisher : Frontiers Media SA
Page : 398 pages
File Size : 11,4 MB
Release : 2020-10-08
Category : Medical
ISBN : 2889660486

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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Placebo and Pain

Author : Luana Colloca
Publisher : Academic Press
Page : 321 pages
File Size : 27,50 MB
Release : 2013-08-28
Category : Medical
ISBN : 0123979315

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The placebo effect continues to fascinate scientists, scholars, and clinicians, resulting in an impressive amount of research, mainly in the field of pain. While recent experimental and clinical studies have unraveled salient aspects of the neurobiological substrates and clinical relevance of pain and placebo analgesia, an authoritative source remained lacking until now. By presenting and integrating a broad range of research, Placebo and Pain enhances readers’ knowledge about placebo and nocebo effects, reexamines the methodology of clinical trials, and improves the therapeutic approaches for patients suffering from pain. Review for Placebo and Pain:“This ambitious book is the first comprehensive and unified presentation of the placebo and nocebo phenomena in the area of pain. Written by the international leading experts in the field, the book provides an accurate up-to-date [work] on placebo and pain dealing with current perspectives and future challenging issues. --Ted Kaptchuk, Associate Professor of Medicine, Harvard Medical School Contains historical aspects of the placebo effect Discusses biological and psychological mechanisms of placebo analgesic responses Reviews implications of the placebo effect for clinical research and pain management Includes methodological and ethical aspects of the placebo effect

Essentials of Clinical Research

Author : Stephen P. Glasser
Publisher : Springer
Page : 462 pages
File Size : 18,16 MB
Release : 2014-06-02
Category : Medical
ISBN : 3319054708

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In its extensively revised and updated Second Edition, this book provides a solid foundation for readers interested in clinical research. Discussion encompasses genetic, pharmacoepidemiologic and implementation research. All chapters have been updated with new information and many new tables have been added to elucidate key points. The book now offers discussion on how to handle missing data when analyzing results, and coverage of Adaptive Designs and Effectiveness Designs and new sections on Comparative Effectiveness Research and Pragmatic Trials. Chapter 6 includes new material on Phase 0 Trials, expanded coverage of Futility Trials, a discussion of Medical Device approval, Off Label Drug use and the role of the FDA in regulating advertising. Additional new information includes the role of pill color and shape in association with the placebo effect and an examination of issues surrounding minority recruitment. The final chapter offers a new section on manuscript preparation along with a discussion of various guidelines being adopted by journals: CONSORT, STROBE, PRISMA, MOOSE and others; and coverage of Conflicts of Interest, Authorship, Coercive Citation, and Disclosures in Industry-Related Associations. Building on the strengths of its predecessor in its comprehensive approach and authoritative advice, the new edition offers more of what has made this book a popular, trusted resource for students and working researchers alike.

Placebo and Pain

Author : Luana Colloca
Publisher : Elsevier Inc. Chapters
Page : 29 pages
File Size : 23,51 MB
Release : 2013-08-28
Category : Medical
ISBN : 012806434X

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The defining circumstances and reasons for promoting healing processes based on placebo and avoiding (undesirable) nocebo effects in clinical practice represent a challenge for translational and patient-oriented medicine. Exploiting placebos and placebo effects for the benefit of the patient requires a rigorous evaluation of potential benefits and harms associated with these interventions. Moreover, any attempts to harness placebo benefits and mitigate nocebo effects in clinical practice should be done consistently with professional norms and integrity, and ethical-legal requirements of informed consent. This chapter systematically discusses the complex issue of professional and ethical requirements in using placebos and placebo effects in pain-related research and practices. Within this scope, some important questions need to be addressed as well: (a) Can placebo analgesic effects produce clinically significant benefits? (b) What translational research is being done, or should be done? (c) What work is being done in this area to enable and encourage doctors to incorporate ethically the concept of placebo and nocebo effects into their work?

Placebo

Author : Fabrizio Benedetti
Publisher : Springer
Page : 307 pages
File Size : 25,85 MB
Release : 2014-10-10
Category : Medical
ISBN : 3662445190

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Due to the recent explosion of placebo research at many levels the Editors believe that a volume on Placebo would be a good addition to the Handbook of Experimental Pharmacology series. In particular, this volume will be built up on a meeting on Placebo which will be held in Tuebingen (Germany) in January 2013, and where the most prominent researchers in this field will present and exchange their ideas. The authors who will be invited to write chapters for this volume will be the very same speakers at this meeting, thus guaranteeing high standard and excellence in the topic that will be treated. The approach of the book is mainly pharmacological, including basic research and clinical trials, and the contents range from different medical conditions and systems, such as pain and the immune system, to different experimental approaches, like in vivo receptor binding and pharmacological/behavioral conditioning. Overall, the volume will give an idea of modern placebo research, of timely concepts in both experimental and clinical pharmacology, as well as of modern methods and tools in neuroscience.

Practical Management of Complex Cancer Pain

Author : Manohar Sharma
Publisher : Oxford Specialist Handbooks in
Page : 321 pages
File Size : 20,32 MB
Release : 2014-02
Category : Medical
ISBN : 0199661626

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Practical Management of Complex Cancer Pain provides practical advice on advanced pain management techniques for cancer pain. Comprehensive case histories give readers insight into the treatment of pain management.