[PDF] The Cutter Incident eBook

Author : Paul A. Offit
Publisher : Yale University Press
Page : 260 pages
File Size : 25,13 MB
Release : 2007-09-18
Category : History
ISBN : 9780300126051

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Vaccines have saved more lives than any other single medical advance. Yet today only four companies make vaccines, and there is a growing crisis in vaccine availability. Why has this happened? This remarkable book recounts for the first time a devastating episode in 1955 at Cutter Laboratories in Berkeley, California, thathas led many pharmaceutical companies to abandon vaccine manufacture. Drawing on interviews with public health officials, pharmaceutical company executives, attorneys, Cutter employees, and victims of the vaccine, as well as on previously unavailable archives, Dr. Paul Offit offers a full account of the Cutter disaster. He describes the nation's relief when the polio vaccine was developed by Jonas Salk in 1955, the production of the vaccine at industrial facilities such as the one operated by Cutter, and the tragedy that occurred when 200,000 people were inadvertently injected with live virulent polio virus: 70,000 became ill, 200 were permanently paralyzed, and 10 died. Dr. Offit also explores how, as a consequence of the tragedy, one jury's verdict set in motion events that eventually suppressed the production of vaccines already licensed and deterred the development of new vaccines that hold the promise of preventing other fatal diseases.

Author : Arthur Allen
Publisher : W. W. Norton & Company
Page : 542 pages
File Size : 13,95 MB
Release : 2008-05-17
Category : Medical
ISBN : 1324036354

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"A timely, fair-minded and crisply written account."—New York Times Book Review Vaccine juxtaposes the stories of brilliant scientists with the industry's struggle to produce safe, effective, and profitable vaccines. It focuses on the role of military and medical authority in the introduction of vaccines and looks at why some parents have resisted this authority. Political and social intrigue have often accompanied vaccination—from the divisive introduction of smallpox inoculation in colonial Boston to the 9,000 lawsuits recently filed by parents convinced that vaccines caused their children's autism. With narrative grace and investigative journalism, Arthur Allen reveals a history illuminated by hope and shrouded by controversy, and he sheds new light on changing notions of health, risk, and the common good.

Author : Institute of Medicine
Publisher : National Academies Press
Page : 481 pages
File Size : 39,22 MB
Release : 1993-01-01
Category : Medical
ISBN : 0309048958

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Childhood immunization is one of the major public health measures of the 20th century and is now receiving special attention from the Clinton administration. At the same time, some parents and health professionals are questioning the safety of vaccines because of the occurrence of rare adverse events after immunization. This volume provides the most thorough literature review available about links between common childhood vaccinesâ€"tetanus, diphtheria, measles, mumps, polio, Haemophilus influenzae b, and hepatitis Bâ€"and specific types of disorders or death. The authors discuss approaches to evidence and causality and examine the consequencesâ€"neurologic and immunologic disorders and deathâ€"linked with immunization. Discussion also includes background information on the development of the vaccines and details about the case reports, clinical trials, and other evidence associating each vaccine with specific disorders. This comprehensive volume will be an important resource to anyone concerned about the immunization controversy: public health officials, pediatricians, attorneys, researchers, and parents.

Author : John Rhodes
Publisher : University of Chicago Press
Page : 185 pages
File Size : 50,20 MB
Release : 2021-04-12
Category : Health & Fitness
ISBN : 022679251X

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Understand the Virus -- Explore the Immune System -- Discover a Vaccine -- Develop Vaccines -- Evaluate the Contenders -- Don't Count on the Magic Bullet -- Overcome the Hurdles -- Embrace Many Solutions.

Author : Thomas Abraham
Publisher : Oxford University Press
Page : 350 pages
File Size : 42,52 MB
Release : 2018-09-01
Category : Medical
ISBN : 1787380874

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In 1988, the World Health Organization launched a twelve-year campaign to wipe out polio. Thirty years and several billion dollars over budget later, the campaign grinds on, vaccinating millions of children and hoping that each new year might see an end to the disease. But success remains elusive, against a surprisingly resilient virus, an unexpectedly weak vaccine and the vagaries of global politics, meeting with indifference from governments and populations alike. How did an innocuous campaign to rid the world of a crippling disease become a hostage of geopolitics? Why do parents refuse to vaccinate their children against polio? And why have poorly paid door-to-door healthworkers been assassinated? Thomas Abraham reports on the ground in search of answers.

Author : Nick Cutter
Publisher : Simon and Schuster
Page : 464 pages
File Size : 43,10 MB
Release : 2014-02-25
Category : Fiction
ISBN : 1476717753

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WINNER OF THE JAMES HERBERT AWARD FOR HORROR WRITING “The Troop scared the hell out of me, and I couldn’t put it down. This is old-school horror at its best.” —Stephen King Once every year, Scoutmaster Tim Riggs leads a troop of boys into the Canadian wilderness for a weekend camping trip—a tradition as comforting and reliable as a good ghost story around a roaring bonfire. But when an unexpected intruder stumbles upon their campsite—shockingly thin, disturbingly pale, and voraciously hungry—Tim and the boys are exposed to something far more frightening than any tale of terror. The human carrier of a bioengineered nightmare. A horror that spreads faster than fear. A harrowing struggle for survival with no escape from the elements, the infected…or one another. Part Lord of the Flies, part 28 Days Later—and all-consuming—this tightly written, edge-of-your-seat thriller takes you deep into the heart of darkness, where fear feeds on sanity…and terror hungers for more.

Author : Jonathan M. Berman
Publisher : MIT Press
Page : 299 pages
File Size : 30,66 MB
Release : 2020-09-08
Category : Social Science
ISBN : 0262539322

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A “clear and insightful” takedown of the anti-vaccination movement, from its 19th-century antecedents to modern-day Facebook activists—with strategies for refuting false claims of friends and family (Financial Times) Vaccines are a documented success story, one of the most successful public health interventions in history. Yet there is a vocal anti-vaccination movement, featuring celebrity activists (including Kennedy scion Robert F. Kennedy Jr. and actress Jenny McCarthy) and the propagation of anti-vax claims through books, documentaries, and social media. In Anti-Vaxxers, Jonathan Berman explores the phenomenon of the anti-vaccination movement, recounting its history from its nineteenth-century antecedents to today’s activism, examining its claims, and suggesting a strategy for countering them. After providing background information on vaccines and how they work, Berman describes resistance to Britain’s Vaccination Act of 1853, showing that the arguments anticipate those made by today’s anti-vaxxers. He discusses the development of new vaccines in the twentieth century, including those protecting against polio and MMR (measles, mumps, rubella), and the debunked paper that linked the MMR vaccine to autism; the CDC conspiracy theory promoted in the documentary Vaxxed; recommendations for an alternative vaccination schedule; Kennedy’s misinformed campaign against thimerosal; and the much-abused religious exemption to vaccination. Anti-vaxxers have changed their minds, but rarely because someone has given them a list of facts. Berman argues that anti-vaccination activism is tied closely to how people see themselves as parents and community members. Effective pro-vaccination efforts should emphasize these cultural aspects rather than battling social media posts.

Author : Michael Kinch
Publisher : Simon and Schuster
Page : 360 pages
File Size : 16,46 MB
Release : 2018-07-03
Category : Science
ISBN : 1681778203

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If you have a child in school, you may have heard stories of long-dormant diseases suddenly reappearing—cases of measles, mumps, rubella, and whooping cough cropping up everywhere from elementary schools to Ivy League universities because a select group of parents refuse to vaccinate their children. Between Hope and Fear tells the remarkable story of vaccine-preventable infectious diseases and their social and political implications. While detailing the history of vaccine invention, Kinch reveals the ominous reality that our victories against vaccine-preventable diseases are not permanent—and could easily be undone. In the tradition of John Barry’s The Great Influenza and Siddhartha Mukherjee’s The Emperor of All Maladies, Between Hope and Fear relates the remarkable intersection of science, technology, and disease that has helped eradicate many of the deadliest plagues known to man.

Author : Charlotte Jacobs
Publisher : Oxford University Press, USA
Page : 588 pages
File Size : 29,26 MB
Release : 2015
Category : Biography & Autobiography
ISBN : 0199334412

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The first full biography of Jonas Salk offers a complete picture of the enigmatic figure, from his early years working on an influenza vaccine--for which he never fully got credit--to his seminal creation of the Polio vaccine, up through his later work to find a cure for AIDS.

Author : Abraham Verghese
Publisher : Random House India
Page : 560 pages
File Size : 11,37 MB
Release : 2012-05-17
Category : Fiction
ISBN : 8184001754

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Marion and Shiva Stone are twin brothers born of a secret union between a beautiful Indian nun and a brash British surgeon. Orphaned by their mother’s death and their father’s disappearance and bound together by a preternatural connection and a shared fascination with medicine, the twins come of age as Ethiopia hovers on the brink of revolution. Moving from Addis Ababa to New York City and back again, Cutting for Stone is an unforgettable story of love and betrayal, medicine and ordinary miracles—and two brothers whose fates are forever intertwined.