[PDF] The Biology Of The Pancreatic Cell eBook

Author : S.L. Howell
Publisher : Elsevier
Page : 371 pages
File Size : 18,28 MB
Release : 1999-04-15
Category : Science
ISBN : 0080877141

GET BOOK

As a result of the key advances made more than 30 years ago, specifically the ability to isolate islets of Langerhans from the pancreas, the ability to measure insulin accurately by immunoasay, and the development of microchemical techniques for studying cells and their components, many research volumes, symposium reports, and original papers have been produced. This explosion of interest has probably had at least three stimuli: 1. the inherent scientific interest in understanding secretion of the pancreatic ß-cell2. the ß-cells relevance to a very common disease3. the availability of funding from specific sources related to diabetes research, for instance, Juvenile Diabetes Foundation International and the British Diabetic Association. As a result of all this activity, detailed scientific literature including research reviews are readily available. Surprisingly enough, there are relatively few attempts to summarize this great bulk of knowledge in a way that is accessible to the newcomer to this field and this book is intended to bridge this gap.

Author : Susumu Seino
Publisher : Springer Science & Business Media
Page : 475 pages
File Size : 38,58 MB
Release : 2008-04-08
Category : Science
ISBN : 4431754520

GET BOOK

The beta cells of the pancreatic islets of Langerhans are the only cells in the body that produce and secrete insulin. This metabolic hormone plays a central role in the maintenance of glucose homeostasis. This book provides a comprehensive review of the beta cell in health and disease. The book’s primary aim is to encourage investigators to become actively involved in diabetes research and the search for new approaches to prevent and treat diabetes.

Author : Stephen Pandol
Publisher : Morgan & Claypool Publishers
Page : 66 pages
File Size : 38,27 MB
Release : 2011
Category : Medical
ISBN : 1615041389

GET BOOK

The secretions of the exocrine pancreas provide for digestion of a meal into components that are then available for processing and absorption by the intestinal epithelium. Without the exocrine pancreas, malabsorption and malnutrition result. This chapter describes the cellular participants responsible for the secretion of digestive enzymes and fluid that in combination provide a pancreatic secretion that accomplishes the digestive functions of the gland. Key cellular participants, the acinar cell and the duct cell, are responsible for digestive enzyme and fluid secretion, respectively, of the exocrine pancreas. This chapter describes the neurohumoral pathways that mediate the pancreatic response to a meal as well as details of the cellular mechanisms that are necessary for the organ responses, including protein synthesis and transport and ion transports, and the regulation of these responses by intracellular signaling systems. Examples of pancreatic diseases resulting from dysfunction in cellular mechanisms provide emphasis of the importance of the normal physiologic mechanisms.

Author :
Publisher : Academic Press
Page : 517 pages
File Size : 40,15 MB
Release : 2014-02-20
Category : Medical
ISBN : 0128004401

GET BOOK

First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Series provides up-to-date information on vitamin and hormone research spanning data from molecular biology to the clinic. A volume can focus on a single molecule or on a disease that is related to vitamins or hormones. A hormone is interpreted broadly so that related substances, such as transmitters, cytokines, growth factors and others can be reviewed. This volume focuses on the pancreatic beta cell. Expertise of the contributors Coverage of a vast array of subjects In depth current information at the molecular to the clinical levels Three-dimensional structures in color Elaborate signaling pathways

Author : Bernhelm Booß-Bavnbek
Publisher : Springer Science & Business Media
Page : 558 pages
File Size : 36,82 MB
Release : 2011-03-02
Category : Science
ISBN : 144196956X

GET BOOK

BetaSys uses the example of regulated exocytosis in pancreatic β-cells, and its relevance to diabetes, to illustrate the major concepts of systems biology, its methods and applications.

Author :
Publisher : Academic Press
Page : 416 pages
File Size : 31,42 MB
Release : 2021-04-06
Category : Science
ISBN : 0128237562

GET BOOK

Pancreatic B Cell Biology in Health and Disease, Volume 360 presents the latest release in this ongoing series on the novel and widely studied physiology of pancreatic cells in homeostasis and under pathogenic conditions. This new volume includes new chapters on a variety of topics, including Pancreatic Beta Cell Dysfunction in Type 1 Diabetes: The Role of Ifn, Sexual Hormones and Diabetes: The Impact in Pancreatic Beta Cell, Pancreatic Beta Cell Dysfunction in Monogenic Diabetes, The Role of MiRNAs In Beta Cell Function, Pancreatic Beta Cell: How Environmental Endocrine Disruptors Alter Its Function, Enteroviral Infections and Pancreatic Beta Cell Dysfunction, and more. Final sections cover Long Non-Coding Rna-Regulated Pathways in Pancreatic Beta Cell: Their Role in Diabetes and Pancreatic Beta Cell Biology in Health and Disease. Provides updated and extensive review articles that focus on different aspects of pancreatic cell biology Offers a wide range of perspectives for basic and translational research Includes original figures that help readers understand the complex pathways involved in cell function in homeostasis and under pathogenic conditions

Author : Vay Liang W. Go
Publisher : Lippincott Williams & Wilkins
Page : 1212 pages
File Size : 37,14 MB
Release : 1993
Category : Medical
ISBN :

GET BOOK

This second, revised edition aims to incorporate the latest advances in research and clinical practice, and has been refocused to provide complete coverage of the endocrine, as well as the exocrine, functions of the pancreas. Over 80 experts provide a definitive account of the biology of the pancreas and the pathobiology, diagnosis, and medical and surgical treatment of all pancreatic diseases.

Author : Anandwardhan A. Hardikar
Publisher : Springer
Page : 332 pages
File Size : 42,4 MB
Release : 2016-10-25
Category : Science
ISBN : 3319453076

GET BOOK

This comprehensive volume discusses in vitro laboratory development of insulin-producing cells. It encompasses multiple aspects of islet biology—from embryonic development and stem cell differentiation to clinical studies in islet transplantation, regulation of islet beta-cell regeneration, pancreatic progenitors, mathematical modelling of islet development, epigenetic regulation, and much more. The chapter authors represent leading laboratories from around the world who contribute their international perspectives and global expertise. Collectively, they provide the reader with a concise yet detailed knowledge of processes and current developments in islet regenerative biology. Pancreatic Islet Biology, part of the Stem Cell Biology and Regenerative Medicine series, is essential reading for researchers and clinicians in stem cells or endocrinology, especially those focusing on diabetes.

Author : Juan Domínguez-Bendala
Publisher : Springer Science & Business Media
Page : 157 pages
File Size : 19,26 MB
Release : 2012-02-10
Category : Science
ISBN : 1607611325

GET BOOK

From the discovery of Pdx1, the first “master gene” of pancreatic development, to the most recent findings on the role of microRNAs in beta cell homeostasis, the last fifteen years have seen an unprecedented advance in our understanding of the precise development and organization of the many different cell types that make up the pancreas. It is now widely acknowledged that the therapeutic differentiation of stem cells into pancreatic cells is an ambitious endeavor that will not succeed without a thorough understanding of the molecular processes underlying the native development of the organ. This book, aimed at experts and students alike, offers a comprehensive review of the state of the art in both pancreatic development and regeneration. The many strategies to differentiate adult and embryonic stem cells into pancreatic beta cells are also discussed in the context of potential therapeutic interventions for type I diabetes.

Author : Md. Shahidul Islam
Publisher : Springer Science & Business Media
Page : 800 pages
File Size : 25,42 MB
Release : 2010-03-10
Category : Medical
ISBN : 9048132711

GET BOOK

When new fellows join my lab, I give them some reading materials so that they can orient themselves in their assignment in a new eld. When fellows leave my lab, some after writing their dissertations, I prefer to give them a book as a symbolic present. I was longing for a book that contained something on more or less eve- thing about the islets. At the same time, I wished it contained information as recent as possible. There are a few such books in the market but they are pretty outdated. I started picking islets myself from October 1990, when I joined the Rolf Luft Center, Karolinska Institutet. Over the years my fascination for islet research remained high. Since last year, I felt a stronger urge to do more for these mysterious and hidden mini-organs that are directly or indirectly involved in the pathogenesis of all forms of diabetes that affects ?250 million people in the world. After I launched the Islet (landesbioscience. com/journals/islets) and founded the Islet Society (isletso- ety. org), there was a momentum that could be utilized to create something equally meaningful i. e. this book. The idea cracked in September 2008. Starting September 19, 2008, I contacted an estimated 90% of the authors who published anything on the islets during 2007–2008 and who could be traced from the internet.