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Developing Synthetic Transport Systems

Author : Alexey Melkikh
Publisher : Springer Science & Business Media
Page : 204 pages
File Size : 42,86 MB
Release : 2013-02-01
Category : Medical
ISBN : 9400758936

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​Understanding the general laws of an effective system for the transport of substances in cells is an important goal of systems and synthetic biology and will help us to answer why the transport subsystem of a cell is arranged as it is. In addition, the construction of models for optimizing transport systems is of considerable importance in the early stages in the development of a functioning protocell. The aim of this book is to describe the latest techniques for the calculation of the optimal parameters of the transport subsystem of a cell at its maximum efficiency. The book will describe linear and nonlinear programming, dynamic programming, game theory for models of ion transport in different types of cells (e.g. mammalian cells, bacteria, plants and fungi). ​

Microbial Transport Systems

Author : Günther Winkelmann
Publisher : Wiley-VCH Verlag GmbH
Page : 488 pages
File Size : 22,49 MB
Release : 2001
Category : Science
ISBN : 9783527303045

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Transport of molecules across the cell membrane is a fundamental process of all living organisms. It is essential for understanding growth, development, nutrition as well as uptake and excretion of exogenous or synthesized molecules. Microbes respresent general and basic functional systems where many transport processes have been studied on a molecular basis. Knowledge of the microbial transport processes will provide new perspectives to treatments by inhibitors, drugs, antibiotics, vitamins, growth promotion compounds, activators and toxic compunds of various kinds.

Anoxygenic Photosynthetic Bacteria

Author : R.E. Blankenship
Publisher : Springer Science & Business Media
Page : 1333 pages
File Size : 14,87 MB
Release : 2006-04-11
Category : Science
ISBN : 0306479540

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Anoxygenic Photosynthetic Bacteria is a comprehensive volume describing all aspects of non-oxygen-evolving photosynthetic bacteria. The 62 chapters are organized into themes of: Taxonomy, physiology and ecology; Molecular structure of pigments and cofactors; Membrane and cell wall structure: Antenna structure and function; Reaction center structure and electron/proton pathways; Cyclic electron transfer; Metabolic processes; Genetics; Regulation of gene expression, and applications. The chapters have all been written by leading experts and present in detail the current understanding of these versatile microorganisms. The book is intended for use by advanced undergraduate and graduate students and senior researchers in the areas of microbiology, genetics, biochemistry, biophysics and biotechnology.

The Science and Applications of Synthetic and Systems Biology

Author : Institute of Medicine
Publisher : National Academies Press
Page : 570 pages
File Size : 40,77 MB
Release : 2011-12-30
Category : Science
ISBN : 0309219396

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Many potential applications of synthetic and systems biology are relevant to the challenges associated with the detection, surveillance, and responses to emerging and re-emerging infectious diseases. On March 14 and 15, 2011, the Institute of Medicine's (IOM's) Forum on Microbial Threats convened a public workshop in Washington, DC, to explore the current state of the science of synthetic biology, including its dependency on systems biology; discussed the different approaches that scientists are taking to engineer, or reengineer, biological systems; and discussed how the tools and approaches of synthetic and systems biology were being applied to mitigate the risks associated with emerging infectious diseases. The Science and Applications of Synthetic and Systems Biology is organized into sections as a topic-by-topic distillation of the presentations and discussions that took place at the workshop. Its purpose is to present information from relevant experience, to delineate a range of pivotal issues and their respective challenges, and to offer differing perspectives on the topic as discussed and described by the workshop participants. This report also includes a collection of individually authored papers and commentary.

Synthetic biology applications in industrial microbiology

Author : Weiwen Zhang
Publisher : Frontiers E-books
Page : 130 pages
File Size : 19,24 MB
Release : 2014-12-03
Category : Bioengineering
ISBN : 288919342X

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Exponentially increasing information on biological organisms coupled with increasing computational power in the past decade have broadened the perspective of fundamental biological research, bringing about considerable promise and unprecedented potential for practical applications in biotechnology. As one emergent discipline, synthetic biology aims to design and engineer novel biologically-based parts, devices, and systems, in addition to redesigning existing, natural biological systems. Although previously relegated to demonstration studies, more recent research in synthetic biology has focused on the rational engineering of industrial microorganisms with the potential to address many of society’s critical challenges. Within the realm of industrial microbiology, progress in the field of synthetic biology has enabled the development of, for example, new biosynthetic pathways for the production of renewable fuels and chemicals, programmable logic controls to regulate and optimize cell function, and robust microbes for the destruction of harmful environmental contaminants. Some of the exciting examples included producing anti-malarial drug, anti- cancer taxol precursor and various biofuel molecules in E. coli and yeast. In addition, these researches have also greatly enhanced our understanding of the cellular machinery and its regulation in some of the industry important microbes, laying an important foundation for further design and engineering of biological function for even greater application. For these reasons, we present here a collection of articles from the leading edge of the field of synthetic biology, with a specific focus on the development in industrial microorganisms. It is the intent of this collection to reach a wide audience whose interests and expertise spans from development of novel synthetic biology methodologies and theories (both experimental and computational) to practical applications seeking to address issues facing the world today.

Research Grants Index

Author : National Institutes of Health (U.S.). Division of Research Grants
Publisher :
Page : 1212 pages
File Size : 26,60 MB
Release : 1975
Category : Medicine
ISBN :

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