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In the final years of the twentieth century, emigres from mechanical and electrical engineering and computer science resolved that if the aim of biology was to understand life, then making life would yield better theories than experimentation. Sophia Roosth, a cultural anthropologist, takes us into the world of these self-named synthetic biologists who, she shows, advocate not experiment but manufacture, not reduction but construction, not analysis but synthesis. Roosth reveals how synthetic biologists make new living things in order to understand better how life works. What we see through her careful questioning is that the biological features, theories, and limits they fasten upon are determined circularly by their own experimental tactics. This is a story of broad interest, because the active, interested making of the synthetic biologists is endemic to the sciences of our time."
Imagining a future in which humans fundamentally reshape the natural world using nanotechnology, synthetic biology, de-extinction, and climate engineering. We have all heard that there are no longer any places left on Earth untouched by humans. The significance of this goes beyond statistics documenting melting glaciers and shrinking species counts. It signals a new geological epoch. In The Synthetic Age, Christopher Preston argues that what is most startling about this coming epoch is not only how much impact humans have had but, more important, how much deliberate shaping they will start to do. Emerging technologies promise to give us the power to take over some of Nature's most basic operations. It is not just that we are exiting the Holocene and entering the Anthropocene; it is that we are leaving behind the time in which planetary change is just the unintended consequence of unbridled industrialism. A world designed by engineers and technicians means the birth of the planet's first Synthetic Age. Preston describes a range of technologies that will reconfigure Earth's very metabolism: nanotechnologies that can restructure natural forms of matter; “molecular manufacturing” that offers unlimited repurposing; synthetic biology's potential to build, not just read, a genome; “biological mini-machines” that can outdesign evolution; the relocation and resurrection of species; and climate engineering attempts to manage solar radiation by synthesizing a volcanic haze, cool surface temperatures by increasing the brightness of clouds, and remove carbon from the atmosphere with artificial trees that capture carbon from the breeze. What does it mean when humans shift from being caretakers of the Earth to being shapers of it? And in whom should we trust to decide the contours of our synthetic future? These questions are too important to be left to the engineers.
From EverQuest to World of Warcraft, online games have evolved from the exclusive domain of computer geeks into an extraordinarily lucrative staple of the entertainment industry. People of all ages and from all walks of life now spend thousands of hours—and dollars—partaking in this popular new brand of escapism. But the line between fantasy and reality is starting to blur. Players have created virtual societies with governments and economies of their own whose currencies now trade against the dollar on eBay at rates higher than the yen. And the players who inhabit these synthetic worlds are starting to spend more time online than at their day jobs. In Synthetic Worlds, Edward Castronova offers the first comprehensive look at the online game industry, exploring its implications for business and culture alike. He starts with the players, giving us a revealing look into the everyday lives of the gamers—outlining what they do in their synthetic worlds and why. He then describes the economies inside these worlds to show how they might dramatically affect real world financial systems, from potential disruptions of markets to new business horizons. Ultimately, he explores the long-term social consequences of online games: If players can inhabit worlds that are more alluring and gratifying than reality, then how can the real world ever compete? Will a day ever come when we spend more time in these synthetic worlds than in our own? Or even more startling, will a day ever come when such questions no longer sound alarmist but instead seem obsolete? With more than ten million active players worldwide—and with Microsoft and Sony pouring hundreds of millions of dollars into video game development—online games have become too big to ignore. Synthetic Worlds spearheads our efforts to come to terms with this virtual reality and its concrete effects. “Illuminating. . . . Castronova’s analysis of the economics of fun is intriguing. Virtual-world economies are designed to make the resulting game interesting and enjoyable for their inhabitants. Many games follow a rags-to-riches storyline, for example. But how can all the players end up in the top 10%? Simple: the upwardly mobile human players need only be a subset of the world's population. An underclass of computer-controlled 'bot' citizens, meanwhile, stays poor forever. Mr. Castronova explains all this with clarity, wit, and a merciful lack of academic jargon.”—The Economist “Synthetic Worlds is a surprisingly profound book about the social, political, and economic issues arising from the emergence of vast multiplayer games on the Internet. What Castronova has realized is that these games, where players contribute considerable labor in exchange for things they value, are not merely like real economies, they are real economies, displaying inflation, fraud, Chinese sweatshops, and some surprising in-game innovations.”—Tim Harford, Chronicle of Higher Education
A Harvard biologist and master inventor explores how new biotechnologies will enable us to bring species back from the dead, unlock vast supplies of renewable energy, and extend human life. In Regenesis, George Church and science writer Ed Regis explore the possibilities of the emerging field of synthetic biology. Synthetic biology, in which living organisms are selectively altered by modifying substantial portions of their genomes, allows for the creation of entirely new species of organisms. These technologies-far from the out-of-control nightmare depicted in science fiction-have the power to improve human and animal health, increase our intelligence, enhance our memory, and even extend our life span. A breathtaking look at the potential of this world-changing technology, Regenesis is nothing less than a guide to the future of life.
Synthetic Biology provides a framework to examine key enabling components in the emerging area of synthetic biology. Chapters contributed by leaders in the field address tools and methodologies developed for engineering biological systems at many levels, including molecular, pathway, network, whole cell, and multi-cell levels. The book highlights exciting practical applications of synthetic biology such as microbial production of biofuels and drugs, artificial cells, synthetic viruses, and artificial photosynthesis. The roles of computers and computational design are discussed, as well as future prospects in the field, including cell-free synthetic biology and engineering synthetic ecosystems. Synthetic biology is the design and construction of new biological entities, such as enzymes, genetic circuits, and cells, or the redesign of existing biological systems. It builds on the advances in molecular, cell, and systems biology and seeks to transform biology in the same way that synthesis transformed chemistry and integrated circuit design transformed computing. The element that distinguishes synthetic biology from traditional molecular and cellular biology is the focus on the design and construction of core components that can be modeled, understood, and tuned to meet specific performance criteria and the assembly of these smaller parts and devices into larger integrated systems that solve specific biotechnology problems. Includes contributions from leaders in the field presents examples of ambitious synthetic biology efforts including creation of artificial cells from scratch, cell-free synthesis of chemicals, fuels, and proteins, engineering of artificial photosynthesis for biofuels production, and creation of unnatural living organisms Describes the latest state-of-the-art tools developed for low-cost synthesis of ever-increasing sizes of DNA and efficient modification of proteins, pathways, and genomes Highlights key technologies for analyzing biological systems at the genomic, proteomic, and metabolomic levels which are especially valuable in pathway, whole cell, and multi-cell applications Details mathematical modeling tools and computational tools which can dramatically increase the speed of the design process as well as reduce the cost of development
The decade of the 1970s, like the 1960s, was one of extremes. Traditional plaids and prints, which were reintroduced, became popular at the same time that bold prints and geometrics, including Op Art and "psychedelic" patterns and colors, characterized the fabric and fashion. Synthetics were everywhere and made into everything, and phrases like "polyester knit" and "stretch knit" elicit visions of '70s staples that are unmistakable. The best way to experience the fabric of a decade is to see it, and this book is entirely dedicated to the sensory, the visual. Nearly 300 close-up color photographs of synthetic and synthetic blends, with informative captions, glossary, and index make this book a treat for designers, historians, and anyone interested in fashion and textiles.
The way electronic instruments are built is changing in a deeply fundamental way. It is making an evolutionary leap to a new method of design that is being called synthetic instruments. This new method promises to be the most significant advance in electronic test and instrumentation since the introduction of automated test equipment (ATE). The switch to synthetic instruments is beginning now, and it will profoundly affect all test and measurement equipment that will be developed in the future. Synthetic instruments are like ordinary instruments in that they are specific to a particular measurement or test. They might be a voltmeter that measures voltage, or a spectrum analyzer that measures spectra. The key, defining difference is this: synthetic instruments are implemented purely in software that runs on general purpose, non-specific measurement hardware with a high speed A/D and D/A at its core. In a synthetic instrument, the software is specific; the hardware is generic. Therefore, the "personality" of a synthetic instrument can be changed in an instant. A voltmeter may be a spectrum analyzer a few seconds later, and then become a power meter, or network analyzer, or oscilloscope. Totally different instruments are implemented on the same hardware and can be switched back and forth in the blink of an eye. This book explains the basics of synthetic instrumentation for the many people that will need to quickly learn about this revolutionary way to design test equipment. This book attempts to demystify the topic, cutting through, commercial hype, and obscure, vague jargon, to get to the heart of the technique. It reveals the important basic underlying concepts, showing people how the synthetic instrument design approach, properly executed, is so effective in creating nstrumentation that out performs traditional approaches to T&M and ATE being used today. provides an overview and complete introduction to this revolutionary new technology enables equipment designers and manufacturers to produce vastly more functional and flexible instrumentation; it's not your father's multimeter!
This revealing study considers the remarkable alliance between chemistry and art from the late eighteenth century to the period immediately following the Second World War. Synthetic Worlds offers fascinating new insights into the place of the material object and the significance of the natural, the organic, and the inorganic in Western aesthetics. Esther Leslie considers how radical innovations in chemistry confounded earlier alchemical and Romantic philosophies of science and nature while profoundly influencing the theories that developed in their wake. She also explores how advances in chemical engineering provided visual artists with new colors, surfaces, coatings, and textures, thus dramatically recasting the way painters approached their work. Ranging from Goethe to Hegel, Blake to the Bauhaus, Synthetic Worlds ultimately considers the astonishing affinities between chemistry and aesthetics more generally. As in science, progress in the arts is always assured, because the impulse to discover is as immutable and timeless as the drive to create.
Eli Rubin takes an innovative approach to consumer culture to explore questions of political consensus and consent and the impact of ideology on everyday life in the former East Germany. Synthetic Socialism explores the history of East Germany through the production and use of a deceptively simple material: plastic. Rubin investigates the connections between the communist government, its Bauhaus-influenced designers, its retooled postwar chemical industry, and its general consumer population. He argues that East Germany was neither a totalitarian state nor a niche society but rather a society shaped by the confluence of unique economic and political circumstances interacting with the concerns of ordinary citizens. To East Germans, Rubin says, plastic was a high-technology material, a symbol of socialism's scientific and economic superiority over capitalism. Most of all, the state and its designers argued, plastic goods were of a particularly special quality, not to be thrown away like products of the wasteful West. Rubin demonstrates that this argument was accepted by the mainstream of East German society, for whom the modern, socialist dimension of a plastics-based everyday life had a deep resonance.