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Author : Raul Fleischmajer
Publisher :
Page : 592 pages
File Size : 30,1 MB
Release : 1990
Category : Collagen
ISBN : 9780897665681
Author : BR. Olsen
Publisher :
Page : pages
File Size : 30,10 MB
Release : 1990
Category :
ISBN :
Author : Jouni Uitto
Publisher : CRC Press
Page : 576 pages
File Size : 34,10 MB
Release : 2021-07-29
Category : Science
ISBN : 1000447227
This book is a collection of works that canvass many of the recent developments in various areas of connective tissue research. It focuses on the structure of the components, molecular organization and pathology of the extracellular matrix.
Author : Raul Fleischmajer
Publisher :
Page : 610 pages
File Size : 28,40 MB
Release : 1990
Category :
ISBN :
This volume contains the proceedings of the second New York Academy of Sciences Conference of Collagen, held on April 3-5, 1989 in Bethesda. We hope that this volume will be a useful reference source book for individuals, postdoctoral fellows, and others who are starting their scientific work in the area of extracellular matrix biology; for clinicians interested in diseases affecting connective tissues; and for established investigators in the need of updating their understanding of collagen molecular biology. Several chapters discuss the structure and molecular cloning of the nonfibrillar collagens. The discovery of these collagens coupled with data on other matrix molecules reveal an unexpected complexity of molecular interactions in the extracellular matrix. These complex interactions may play a fundamental role in the assembly of extracellular matrices during development. Therefore, this book will be of interest to developmental biologists. (JES).
Author : Derek J. Chadwick
Publisher : John Wiley & Sons
Page : 374 pages
File Size : 45,33 MB
Release : 2008-04-30
Category : Science
ISBN : 0470514787
Drawing together contributions from a diverse group of international experts in the field, this collection of papers examines the biology and pathology of elastin at the molecular level. Topics include the structure, ultrastructure and function of elastin; elastin regulation; elastin's role in aging, lung development and disease and atherosclerosis; as well as related aspects of pharmacology and nutrition.
Author : Richard Maynes
Publisher : Elsevier
Page : 328 pages
File Size : 32,6 MB
Release : 2012-12-02
Category : Science
ISBN : 0323155715
Structure and Function of Collagen Types is a collection of articles that reviews the different types of collagens (Type I to XI). Each article focuses on a particular type of collagen and written by leading investigators in the collagen field. The book begins with a review of the fibril forming collagens (types I, II, and III) and traces the early work on the structure of these collagens to our knowledge of the structure of the collagen genes. This chapter is followed by a detailed description of type IV (basement membrane) collagen. Chapter 3 addresses the biosynthesis and chain assembly of type V collagen. The evidence that type VI collagen is assembled to form tetramers is presented in chapter 4. The subsequent article shows that type VII collagens are assembled to form partially overlapping dimers. Chapter 6 presents the structure of type VIII collagen. Chapters 7, 8, and 9 discuss the structure and characteristics of collagens that are synthesized by cartilaginous tissues and these are designated as type IX, type X, and type XI. The final chapter reviews the recombinant DNA techniques used to investigate collagen structure and the possibility to recognize new collagen types from a cDNA library. Physiologists, cell biologists, and researchers in the field of collagen will find the text very insightful.
Author : Peter Fratzl
Publisher : Springer Science & Business Media
Page : 516 pages
File Size : 22,34 MB
Release : 2008-05-10
Category : Technology & Engineering
ISBN : 0387739068
Not only does this book provide a comprehensive review of current research advances in collagen structure and mechanics, it also explores this biological macromolecule’s many applications in biomaterials and tissue engineering. Readers gain an understanding of the structure and mechanical behavior of type I collagen and collagen-based tissues in vertebrates across all length scales, from the molecular (nano) to the organ (macro) level.
Author : Eugene J. Kucharz
Publisher : Springer Science & Business Media
Page : 429 pages
File Size : 47,13 MB
Release : 2012-12-06
Category : Science
ISBN : 3642761976
This book describes every manner in which collagen is involved in normal anddisease-altered states of the various organs and systems. In the first part of the book the biochemical aspects of collagens are reviewed, including their structure, heterogeneity, syntheses, and degradation. The main part focuses on the involvement of collagen in bone, cartilage, tendon, muscle, heart, vessels, lungs, liver, skin, eye, ear, teeth, periodontal tissues, kidneys and reproductive, hemopoietic,and nervous systems. The influence of radiation and nutrition on collagen, the role of collagen in neoplasms, the hormonal control of its metabolism, immunobiology and the pharmacology of collagen are also described. The most important feature of the book is the comprehensive review of the medical aspects of collagen, from those known in detail to those only hypothesized including hereditary disorders affecting collagen and so-called collagen diseases. Each chapter reviewsknown or possible mechanisms of collagen involvement and changes in indices of collagen which can be measured in clinical practice to monitor these phenomena. The fact that collagen is involved into the pathophysiology of almost all organs and body systems means that physicians in almost all branches of medicine will find this book of great interest.
Author : Margit Pavelka
Publisher : Springer Science & Business Media
Page : 340 pages
File Size : 30,28 MB
Release : 2005-12-05
Category : Medical
ISBN : 3211263926
The period between 1950 and 1980 were the golden It also provides unique insights into how pathological years of transmission electron microscopy and pro- processes affect cell organization. duced a plethora of new information on the structure of This information is vital to current work in which cells that was coupled to and followed by biochemical the emphasis is on integrating approaches from p- and functional studies. TEM was king and each micro- teomics, molecular biology, molecular imaging and graph of a new object produced new information that physiology, and pathology to understand cell functions led to new insights on cell and tissue organization and and derangements in disease. In this current era, there is their functions. The quality of data represented by the a growing tendency to substitute modern light mic- images of cells and tissues had been perfected to a very scopic techniques for electron microscopy because it is high level by the great microscopists of the era including less technically demanding and is more readily available Palade, Porter, Fawcett, Sjostrand, Rhodin and many to researchers. This atlas reminds us that the infor- others. At present, the images that we see in leading tion obtained by electron microscopy is invaluable and journals for the most part do not reach the same techni- has no substitute.
Author : Margit Pavelka
Publisher : Springer Science & Business Media
Page : 366 pages
File Size : 37,33 MB
Release : 2010-07-16
Category : Science
ISBN : 3211993908
The period between 1950 and 1980 were the golden unique insights into how pathological processes affect years of transmission electron microscopy and produced cell organization. a plethora of new information on the structure of cells This information is vital to current work in which that was coupled to and followed by biochemical and the emphasis is on integrating approaches from functional studies. TEM was king and each micrograph proteomics, molecular biology, genetics, genomics, of a new object produced new information that led to molecular imaging and physiology and pathology to novel insights on cell and tissue organization and their understand cell functions and derangements in disease. functions. The quality of data represented by the images In this current era, there is a growing tendency to of cell and tissues had been perfected to a very high level substitut e modern light microscopic techniques for by the great microscopists of that era including Palade, electron microscopy, because it is less technically Porter, Fawcett, Sjostrand, Rhodin and many others. At demanding and is more readily available to researchers- present, the images that we see in leading journals for This atlas reminds us that the information obtained by the most part do not reach the same technical level and electron microscopy is invaluable and has no substitute.