Author : Piet W.N.M. van Leeuwen
Publisher : Thieme
Page : 780 pages
File Size : 42,20 MB
Release : 2014-05-14
Category : Science
ISBN : 3131765518
The two-volume set on C-1 Building Blocks in Organic Synthesis critically reviews the state of the art of a wide variety of reactions by which one carbon atom is added to an organic molecule, forming a C-C bond. In spite of the numerous classic reactions of this kind, there has been enormous progress in recent years, especially for those reactions involving catalytic methods. Introduction of substituted methyl groups is a major challenge and only very recently the first catalysts have been discovered that enable the introduction of fluoromethyl groups in aromatics.