[PDF] Respiratory Control And Lung Development In The Fetus And Newborn eBook

Author : Alan H. Jobe
Publisher : Cambridge University Press
Page : pages
File Size : 35,59 MB
Release : 2016-04-18
Category : Medical
ISBN : 1316665178

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Lung disease affects more than 600 million people worldwide. While some of these lung diseases have an obvious developmental component, there is growing appreciation that processes and pathways critical for normal lung development are also important for postnatal tissue homeostasis and are dysregulated in lung disease. This book provides an authoritative review of fetal and neonatal lung development and is designed to provide a diverse group of scientists, spanning the basic to clinical research spectrum, with the latest developments on the cellular and molecular mechanisms of normal lung development and injury-repair processes, and how they are dysregulated in disease. The book covers genetics, omics, and systems biology as well as new imaging techniques that are transforming studies of lung development. The reader will learn where the field of lung development has been, where it is presently, and where it is going in order to improve outcomes for patients with common and rare lung diseases.

Author : D.V. Walters
Publisher : Springer Science & Business Media
Page : 302 pages
File Size : 47,98 MB
Release : 2012-12-06
Category : Medical
ISBN : 9400941552

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L. B. STRANG The past 25 years have seen a remarkable growth in our knowledge of lung development in its structural, physiological and biochemical dimensions. Much of the impetus for research leading to new knowledge has derived from the perception that many respiratory disorders in the newborn infant are due to defective development or maladaption of some component or components of the respiratory system. Thus, to cite one example, surfac tant deficiency is clearly seen to be the cause of atelectasis in hyaline mem brane disease; and to cite another, it is widely accepted that the mechanisms controlling patency of the ductus arteriosus and pulmonary vascular resistance also determine the right-to-Ieft or left-to-right shunting frequently observed in the course of neonatal respiratory disorders. There are, however, areas of physiological knowledge - such as those relating to respiratory control and to liquid formation and absorption - which are clearly of great relevance to lung adaptation at birth but where it has not yet proved possible to link a specific clinical state to the malfunction of a particular mechanism. In planning this symposium an attempt was made to organize the material in an orderly manner, starting with the embryonic and fetal stages of growth and development, continuing with respiratory control and the role of surfactant in lung aeration at birth, and ending with the treatment of neonatal respiratory disorders.

Author : Claude Gaultier
Publisher : Springer
Page : 464 pages
File Size : 49,46 MB
Release : 2013-05-27
Category : Medical
ISBN : 1461475376

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Knowledge about the mechanisms of lung development has been growing rapidly, especially with regard to cellular and molecular aspects of growth and differentiation. This authoritative international volume reviews key aspects of lung development in health and disease by providing a comprehensive review of the complex series of cellular and molecular interactions required for lung development. It covers such topics as pulmonary hypoplasia, effects of malnutrition, and pulmaonary angiogenesis. An indispensable reference for all those involved in studying or treating lung disease in neonates and children, the book offers a unique view of the development of this essential organ.

Author : Oomen P. Mathew
Publisher : CRC Press
Page : 600 pages
File Size : 35,15 MB
Release : 2003-01-28
Category : Medical
ISBN : 0203912020

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This text analyses the pathophysiology, diagnosis, treatment and control of respiratory disorders in the newborn infant. It explores the mechanisms, patterns and factors influencing respiratory activity and dysfunction, as well as the aetiology, management and evaluation of conditions such as respiratory distress syndrome, bronchopulmonary dysplasi

Author : Mark A. Hanson
Publisher : Cambridge University Press
Page : 418 pages
File Size : 29,14 MB
Release : 1994-10-27
Category : Medical
ISBN : 9780521417655

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This, the second in the Fetus and Neonate series, concentrates on breathing. The book is divided into sections on physiology, pathophysiology and clinical applications. Recent research and concepts about fetal breathing, the transitions at birth and the control of post-natal breathing are reviewed. The roles of pathophysiological processes in the aetiology of respiratory diseases are discussed and important new developments in diagnosis and treatment are reviewed. The book is written by international authorities in the field, who are active researchers in clinical and basic science as well as practitioners in this area of medicine. It will serve as a valuable source of information for those involved in research in perinatal breathing, or training in paediatrics, neonatology and obstetrics. It will also stimulate the interest of a wider range of health care professionals concerned with keeping abreast of new ideas in this important area of medicine.

Author : Hany Aly
Publisher : BoD – Books on Demand
Page : 180 pages
File Size : 47,18 MB
Release : 2016-08-31
Category : Medical
ISBN : 9535125745

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In this book, you'll learn multiple new aspects of respiratory management of the newborn. For example, ventilator management of infants with unusually severe bronchopulmonary dysplasia and infants with omphalocele is discussed, as well as positioning of endotracheal tube in extremely low birth weight infants, noninvasive respiratory support, utilization of a protocol-driven respiratory management, and more. This book includes a chapter on noninvasive respiratory function monitoring during chest compression, analyzing the efficacy and quality of chest compression and exhaled carbon dioxide. It also provides an overview on new trends in the management of fetal and transitioning lungs in infants delivered prematurely. Lastly, the book includes a chapter on neonatal encephalopathy treated with hypothermia along with mechanical ventilation. The interaction of cooling with respiration and the strategies to optimize oxygenation and ventilation in asphyxiated newborns are discussed.

Author : Eduardo Bancalari
Publisher : Elsevier Health Sciences
Page : 828 pages
File Size : 42,63 MB
Release : 2008-03-06
Category : Medical
ISBN : 1437710867

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This exciting new reference brings you information about the most controversial pulmonary challenges you face in your practice. The book confidently tackles these subjects and gives seasoned advice on the latest diagnostic and treatment strategies using evidence-based medicine wherever possible. It gives you the latest information you need to keep pace with the fast-paced, dynamic environment of neonatology. Addresses controversial topics head on, so you can decide how to handle these difficult practice issues. Serves as the bridge between the latest cutting-edge research and its application to clinical practice. Assembles a world-class group of neonatologists, representing the true leaders of the specialty, to ensure the most authoritative content available.

Author : Philip M Farrell
Publisher : Academic Press
Page : 334 pages
File Size : 15,47 MB
Release : 2013-09-03
Category : Medical
ISBN : 1483269124

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Lung Development: Biological and Clinical Perspectives, Volume II: Neonatal Respiratory Distress is a collection of papers that addresses the needs of small infants who have respiratory diseases. This volume deals with fetal lung development with emphasis on hyaline membrane disease. This book also presents basic information on pulmonary surfactant in the clinical area, particularly in 1) diagnosis and movement of neonatal respiratory distress; 2) prenatal assessment of fetal lung maturity; and 3) prevention of hyaline membrane disease with corticosteroid therapy. One paper reviews the essential clinical aspects of hyaline membrane disease, while another paper discusses data of the physiology of surfactant from a patient with hyaline membrane disease. Another paper examines the radiology of hyaline membrane disease, transient tachypnea of the newborn, and bronchopulmonary dysplasia; this paper also describes the radiographic techniques to be applied on infants. Other papers cite a treatment using antepartum glucocorticoid, as well as other clinical trials involving antenatal corticosteroid. One paper proposes a design and organization of a multicenter clinical trial that will study the effects of corticosteroid in the development of the human lung. This book can prove useful for pediatricians, specialists in respiratory diseases, and researchers whose work involves cardiovascular medicine and radiology.

Author : Eduardo Bancalari
Publisher : Elsevier Health Sciences
Page : 464 pages
File Size : 13,96 MB
Release : 2018-06-19
Category : Medical
ISBN : 0323568750

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Dr. Richard Polin’s Neonatology Questions and Controversies series highlights the most challenging aspects of neonatal care, offering trustworthy guidance on up-to-date diagnostic and treatment options in the field. In each volume, renowned experts address the clinical problems of greatest concern to today’s practitioners, helping you handle difficult practice issues and provide optimal, evidence-based care to every patient. Stay fully up to date in this fast-changing field with The Newborn Lung, 3rd Edition. The most current clinical information throughout, including key management strategies that may reduce some of the chronic sequelae of neonatal respiratory failure. New content on the role of microbiome in lung injury and lung development. Current coverage of non-invasive respiratory support, perinatal events and their influence on lung development and injury, cell-based lung therapy, automation of respiratory support, and oxygenation targeting in preterm infants. Consistent chapter organization to help you find information quickly and easily. The most authoritative advice available from world-class neonatologists who share their knowledge of new trends and developments in neonatal care. Purchase each volume individually, or get the entire 7-volume set! Gastroenterology and Nutrition Hematology, Immunology and Genetics Hemodynamics and Cardiology Infectious Disease and Pharmacology New Volume! Nephrology and Fluid/Electrolyte Physiology Neurology The Newborn Lung