[PDF] Reperfusion Therapy For Acute Ischemic Stroke eBook

Author : Giuseppe D’Aliberti
Publisher : Springer
Page : 103 pages
File Size : 17,78 MB
Release : 2016-11-22
Category : Medical
ISBN : 3319317059

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This book provides detailed practical guidance on the management of acute ischemic stroke in the clinical settings encountered in daily practice. Real-life cases are used to depict a wide range of clinical scenarios and to highlight significant aspects of management of ischemic stroke. In addition, diagnostic and therapeutic protocols are presented and helpful decision-making algorithms are provided that are specific to the different professionals involved in delivery of acute stroke care and to differing types of hospital facility. The coverage is completed by the inclusion of up-to-date scientific background information relevant to diagnosis and therapy. Throughout, the approach adopted is both practical and multidisciplinary. The book will be of value for all practitioners involved in the provision of acute stroke care, and also for medical students.

Author : R. Gilberto González
Publisher : Springer Science & Business Media
Page : 299 pages
File Size : 33,64 MB
Release : 2010-10-05
Category : Medical
ISBN : 3642127517

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This updated second edition of Acute Ischemic Stroke: Imaging and Intervention provides a comprehensive account of the state of the art in the diagnosis and treatment of acute ischemic stroke. The basic format of the first edition has been retained, with sections on fundamentals such as pathophysiology and causes, imaging techniques and interventions. However, each chapter has been revised to reflect the important recent progress in advanced neuroimaging and the use of interventional tools. In addition, a new chapter is included on the classification instruments for ischemic stroke and their use in predicting outcomes and therapeutic triage. All of the authors are internationally recognized experts and members of the interdisciplinary stroke team at the Massachusetts General Hospital and Harvard Medical School. The text is supported by numerous informative illustrations, and ease of reference is ensured through the inclusion of suitable tables. This book will serve as a unique source of up-to-date information for neurologists, emergency physicians, radiologists and other health care providers who care for the patient with acute ischemic stroke.

Author : Takenori Yamaguchi
Publisher : Springer Science & Business Media
Page : 358 pages
File Size : 32,66 MB
Release : 2012-12-06
Category : Medical
ISBN : 443168459X

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On the threshold of an exciting new era for acute stroke diagnosis and treatment, the Third International Symposium on Thrombolytic Therapy in Acute Ischemic Stroke was held in Nara, Japan, in April 1994. The symposium brought together some 200 basic and clinical scientists for presentations and discussions of issues vital to the understanding of thrombolytic therapy. This volume compiles the major presentations of the symposium, with attention to applications of new diagnostic measures such as diffusion and perfusion MRI, contrast-enhanced transcranial Doppler and angioscopy. Other presentations examine the mechanisms of ischemia/reperfusion injury, hemorrhagic transformation, and reocclusion, with reviews of recent developments in thrombolytic agents. The proceedings of the symposium will be of special interest to researchers, physicians, and students in the fields of neurology, neurosurgery, and nuclear medicine, as well as those in pharmacology, critical care medicine, and related fields.

Author : Rosa Fortunata Musolino
Publisher :
Page : pages
File Size : 49,78 MB
Release : 2017
Category :
ISBN :

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The global population aging will accelerate in the coming decade. 30% of stroke patients are older than 80. Findings regarding i.v. rt-PA and mechanical thrombectomy in aged patients lead to uncertainty. This observational study aims to evaluate the safety and effectiveness of reperfusion therapies in over 90-year-old patients with acute ischemic stroke. We retrospectively evaluated ischemic stroke patients, consecutively admitted to our stroke center, aged over 90 and divided into two groups: treated (Tp) and not treated (NTp). Primary end-points were variation of NIHSS from admission to discharge, hemorrhagic transformation, and 3-month mRS. Secondary end-points were the length of hospitalization and in-hospital mortality. Over 72 patients included, 21 were treated with rt-PA, 5 with mechanical thrombectomy, and 3 with bridging therapy. We found no differences in cardiovascular risk factors between the two groups. We found clinical improvement in both groups, with the Tp group showing a significant more improvement compared to the NTp group (Figure 1: u0394NIHSS 5,76 DS 5,35 vs 2,8 DS 4,91; p

Author : Werner Hacke
Publisher : Springer Science & Business Media
Page : 355 pages
File Size : 12,57 MB
Release : 2012-12-06
Category : Medical
ISBN : 3642764398

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During the last decade scientists in both basic and clinical research have renew ed their interest in the potential role of thrombolytic therapy in the treatment of acute ischemic stroke. The reevaluation of this approach was kindled by our growing knowledge of the pathogenesis of thrombotic and embolic stroke and by the development of new thrombolytic agents. With no proven therapy for acute ischemic stroke available, the potential value of early pharmacologic recanalization of occluded vessels in the management of acute stroke patients - an approach that has been supported by animal experiments and a limited number of uncontrolled clinical pilot studies - is again under scrutiny. A sym posium on "Thrombolysis in Acute Cerebral Ischemia" was held in Heidel berg, Germany, in May 1990 to summarize and discuss the pathophysiological background for thrombolysis in acute ischemic stroke and the recent ex perimental and clinical experience with the new generation of thrombolytic agents. The editors are fortunate to be able to include authoritative manuscripts from almost all the speakers at the symposium. These include reports of work by the most active investigators in this challenging field. The editors wish to express their gratitude to all the contributors for the additional work they have undertaken. Additionally, we would like to thank Springer-Verlag, Heidelberg, for its generous assistance in the preparation and rapid publication of this volume. Heidelberg, August 1990 WERNER HACKE GREGORY J. DEL ZopPO MATTHIAS HIRSCHBERG Contents I.

Author : Michel T. Torbey
Publisher : Cambridge University Press
Page : 395 pages
File Size : 40,97 MB
Release : 2013-07-18
Category : Medical
ISBN : 1107634725

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An essential companion for busy professionals seeking to navigate stroke-related clinical situations successfully and make quick informed treatment decisions.

Author : Gregory J. DelZoppo
Publisher : Springer Science & Business Media
Page : 485 pages
File Size : 45,69 MB
Release : 2012-12-06
Category : Medical
ISBN : 364278061X

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Over the last decade, interest in treatment of ischemic stroke has increased significantly. Perhaps the single most important feature of attempts to improve the outcome of stroke patients has been that the interventions be applied within the very early hours of stroke symptoms. This has spawned efforts to understand the vascular and neuronal responses to cerebral artery reperfusion experimentally. Important prospective clinical studies of thrombolysis in acute ischemic stroke have been completed, and large placebo-controlled, symptom-based studies are now underway worldwide. Here, we consider the central features of those studies, their experimental basis, and the future importance of adjunctive therapies to recanalization in focal brain ischemia acutely. Risks and benefits are discussed. This collection benefits from the opinions of experts and workers in this rapidly evolving and exciting field.