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Author : Martin C. Michel Publisher : Springer Science & Business Media Page : 556 pages File Size : 44,64 MB Release : 2012-12-06 Category : Medical ISBN : 3642187641
After a little more than 20 years since the original discovery of neuropeptide Y (NPY) by Tatemoto and colleagues, the field of NPY research has made remarkable progress and is coming of age.The present volume addresses all major topics in connection with NPY and related peptides by established leaders in their respective areas. Experienced NPY-aficionados will certainly find new and useful additional information in this volume and newcomers to the field will hopefully discover how much exciting research this still has to offer.
Hormonal Proteins and Peptides, Volume V: Lipotropin and Related Peptides deals with peptides that have neurobiological properties. This book consists of five chapters. Chapter 1 reviews the chemistry of melanotropins, while Chapter 2 describes the most potent morphinelike peptide, ?-endorphin. The third chapter summarizes the chemistry and biology of lipotropins that were discovered and characterized from 1964 to 1965. Chapter 4 examines the properties and physiological role of neurophysins. A historical perspective of the achievements of the Uppsala School regarding the separation methods and biographical sketch of Arne Tiselius are presented at the last chapter. This book is recommended for endocirnologists, clinicians, and students researching on lipotropins.
Author : Alexander I. Agoulnik Publisher : Springer Science & Business Media Page : 161 pages File Size : 10,72 MB Release : 2008-12-19 Category : Medical ISBN : 0387746722
This comprehensive book contains the latest information on diverse biological functions of relaxin and related peptide found since the recent discovery of relaxin receptors. It also describes the evolution of relaxin family peptides and their receptors, molecular mechanisms of ligand/receptor interaction and the analysis of activated signaling pathways.
Author : William F. Colmers Publisher : Springer Science & Business Media Page : 577 pages File Size : 12,70 MB Release : 1993-03-24 Category : Medical ISBN : 1592594654
Leading experts critically summarize the state of knowledge concerning the molecular, anatomical, physiological, and behavioral aspects of NPY and its congeners. Each article provides a comprehensive and in-depth survey, an overview of the role of NPY in the discipline covered, a discussion of the likely future direction that the field will take, and an up-to-date bibliography. Chapters include a treatment of the evolution of the PP family of genes, the structure of the NPY gene, and the distribution of NPY on the cardiovascular system, actions of NPY on the electrophysiological properties of nerve cells, and the effects of NPY on feeding and behavior. The chapters are written in an accessible style and serve both as an introduction to the field and as an extensive and detailed treatment of the current state of knowledge.
The need to continually discover new agents for the control or treatment of invertebrate pests and pathogens is undeniable. Agriculture, both animal and plant, succeeds only to the extent that arthropod and helminth consumers, vectors and pathogens can be kept at bay. Humans and their companion animals are also plagued by invertebrate parasites. The deployment of chemical agents for these purposes inevitably elicits the selection of resistant populations of the targets of control, necessitating a regular introduction of new kinds of molecules. Experience in other areas of chemotherapy has shown that a thorough understanding of the biology of disease is an essential platform upon which to build a discovery program. Unfortunately, investment of research resources into understanding the basic physiology of invertebrates as a strategy to illuminate new molecular targets for pesticide and parasiticide discovery has been scarce, and the pace of introduction of new molecules for these indications has been slowed as a result. An exciting and so far unexploited area to explore in this regard is invertebrate neuropeptide physiology. This book was assembled to focus attention on this promising field by compiling a comprehensive review of recent research on neuropeptides in arthropods and helminths, with contributions from many of the leading laboratories working on these systems.
Author : Ralph W. Jack Publisher : Springer Science & Business Media Page : 326 pages File Size : 22,7 MB Release : 2013-03-09 Category : Science ISBN : 366208239X
In the last 10 years a proliferation of information concerning the lantibiotics and related peptide antibiotics has come to the fore. This is the first book to summarize this information comprehensively and concisely. Unlike other reviews, which consider the lantibiotics in isolation, this book brings together for the first time the concepts and interrelationships between lantibiotics and other antibiotics, bacteriocins and antimicrobial peptides. This conceptualization should stimulate new ideas, discussion and research in many areas of antibiotic research.
The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volumehas been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. More than 275 volumes have been published (all of them still in print) and much of the material is relevant even today-truly an essential publication for researchers in all fields of life sciences. Key Features * Solid-phase peptide synthesis * Applications of peptides for structural and biological studies * Characterization of synthetic peptides