[PDF] Quality Control And Evaluation Of Herbal Drugs eBook

Author : Pulok K. Mukherjee
Publisher : Elsevier
Page : 784 pages
File Size : 20,33 MB
Release : 2019-05-30
Category : Science
ISBN : 0128133988

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Quality Control and Evaluation of Herbal Drugs brings together current thinking and practices for evaluation of natural products and traditional medicines. The use of herbal medicine in therapeutics is on the rise in both developed and developing countries and this book facilitates the necessary development of quality standards for these medicines.This book elucidates on various challenges and opportunities for quality evaluation of herbal drugs with several integrated approaches including metabolomics, chemoprofiling, marker analysis, stability testing, good practices for manufacturing, clinical aspects, Ethnopharmacology and Ethnomedicine inspired drug development. Written by Prof. Pulok K Mukherjee, a leader in this field; the book highlights on various methods, techniques and approaches for evaluating the purity, quality, safety and efficacy of herbal drugs. Particular attention is paid to methods that assess these drugs’ activity, the compounds responsible and their underlying mechanisms of action. The book describes the quality control parameters followed in India and other countries, including Japan, China, Bangladesh, and other Asian countries, as well as the regulatory profiles of the European Union and North America. This book will be useful in bio-prospecting of natural products and traditional medicine-inspired drug discovery and development. Provides new information on the research and development of natural remedies - essential reading on the study and use of natural resources for preventative or healing purposes Brings together current thinking and practices in quality control and standardization of herbal drugs highlighting several integrated approaches for metabolomics, chemo-profiling and marker analysis Aids in developing knowledge of various techniques including macroscopy, microscopy, HPTLC, HPLC, LC-MS/MS, GC-MS etc. with the development of integrated methods for evaluation of botanicals used in traditional medicine Assessment of herbal drugs through bio-analytical techniques, bioassay guided isolation, enzyme inhibition, pharmacological, microbiological, antiviral assays and safety related quality issues References global organizations, such as the WHO, USFDA, CDSCO, AYUSH, TCM and others to serve as a comprehensive document for enforcement agencies, NGOs and regulatory authorities

Author : Iqbal Ahmad
Publisher : John Wiley & Sons
Page : 404 pages
File Size : 43,52 MB
Release : 2006-12-13
Category : Medical
ISBN : 3527609539

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This timely and original handbook paves the way to success in plant-based drug development, systematically addressing the issues facing a pharmaceutical scientist who wants to turn a plant compound into a safe and effective drug. Plant pharmacologists from around the world demonstrate the potentials and pitfalls involved, with many of the studies and experiments reported here published for the first time. The result is a valuable source of information unavailable elsewhere.

Author : Ravindra Kumar Pandey
Publisher : CRC Press
Page : 214 pages
File Size : 44,75 MB
Release : 2018-07-03
Category : Health & Fitness
ISBN : 0429682824

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Due to the increase in the consumption of herbal medicine, there is a need to know which scientifically based methods are appropriate for assessing the quality of herbal medicines. Fingerprinting has emerged as a suitable technique for quality estimation. Chemical markers are used for evaluation of herbal medicines. Identification and quantification of these chemical markers are crucial for quality control of herbal medicines. This book provides updated knowledge on methodology, quality assessment, toxicity analysis and medicinal values of natural compounds.

Author : World Health Organization
Publisher : World Health Organization
Page : 122 pages
File Size : 18,3 MB
Release : 1998
Category : Medical
ISBN : 9241545100

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A collection of test procedures for assessing the identity, purity, and content of medicinal plant materials, including determination of pesticide residues, arsenic and heavy metals. Intended to assist national laboratories engaged in drug quality control, the manual responds to the growing use of medicinal plants, the special quality problems they pose, and the corresponding need for international guidance on reliable methods for quality control. Recommended procedures - whether involving visual inspection or the use of thin-layer chromatography for the qualitative determination of impurities - should also prove useful to the pharmaceutical industry and pharmacists working with these materials.

Author : Iris F. F. Benzie
Publisher : CRC Press
Page : 500 pages
File Size : 25,35 MB
Release : 2011-03-28
Category : Health & Fitness
ISBN : 1439807167

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The global popularity of herbal supplements and the promise they hold in treating various disease states has caused an unprecedented interest in understanding the molecular basis of the biological activity of traditional remedies. Herbal Medicine: Biomolecular and Clinical Aspects focuses on presenting current scientific evidence of biomolecular ef

Author : Pulok K. Mukherjee
Publisher : Elsevier
Page : 858 pages
File Size : 21,96 MB
Release : 2022-07-12
Category : Business & Economics
ISBN : 0323984568

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Evidence-Based Validation of Herbal Medicines: Translational Research on Botanicals brings together current thinking and practice in the characterization and validation of natural products. The book describes different approaches and techniques for evaluating the quality, safety and efficacy of herbal medicine, particularly methods to assess their activity and understand compounds responsible and their probable underlying mechanisms of action. This book brings together the views, expertise and experiences of scientific experts in the field of medicinal plant research, hence it will be useful for researcher who want to know more about the natural lead with their validation and also useful to exploit traditional medicines. Includes state-of-the-art methods for detecting, isolating and performing structure elucidation by degradation and spectroscopic techniques Highlights the trends in validation and value addition of herbal medicine with different scientific approaches used in therapeutics Contains several all-new chapters on topics such as traditional-medicine-inspired drug development to treat emerging viral diseases, medicinal plants in antimicrobial resistance, TLC bio profiling, botanicals as medicinal foods, bioprospecting and bioassay-guided isolation of medicinal plants, immunomodulators from medicinal plants, and more

Author : A.N.M. Alamgir
Publisher : Springer
Page : 554 pages
File Size : 39,94 MB
Release : 2017-09-06
Category : Medical
ISBN : 3319638629

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This volume focuses on the importance of therapeutically active compounds of natural origin. Natural materials from plants, microbes, animals, marine organisms and minerals are important sources of modern drugs. Beginning with two chapters on the development and definition of the interdisciplinary field of pharmacognosy, the volume offers up-to-date information on natural and biosynthetic sources of drugs, classification of crude drugs, pharmacognosical botany, examples of medical application, WHO ́s guidelines and intellectual property rights for herbal products.

Author : Yukihiro Shoyama
Publisher : BoD – Books on Demand
Page : 296 pages
File Size : 20,83 MB
Release : 2011-11-04
Category : Medical
ISBN : 9533076828

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The authors of this thematic issue provide a comprehensive summary of most recent knowledge and references on quality control in wide fields. Quality control is essential for natural products like natural medicine and related food products. In this issue fifteen chapters have been included, discussing in detail various aspects of quality control. It will certainly prove useful not only for phytochemical researchers, but also many scientists working in numerous fields. Much effort has been invested by the contributors to share current information. Without their efforts and input 'Quality Control of Herbal Medicine and Related Areas' could not exist.

Author :
Publisher : World Scientific
Page : 439 pages
File Size : 21,47 MB
Release : 2015-07-23
Category : History
ISBN : 1938368355

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"Today the chemical analysis is the dominant direction of the quality control system of TCM and natural medicines. But it is difficult to measure the quality for TCM herbs by detecting solely the presence / absence of a single or small number of marker components at very low concentration, especially for the herbs derived from mutliorigins and produced from wide localities, as well as those with unknown principle bioactive components. From this standpoint, it is necessary to use multidisciplinary technologies, integrating the morphological authentication and chemical analysis, qualitative detection and quantitative determination, and physic-chemical analysis and bioassay, in order to distinguish the authentic herb from the adulterant, the superior from the inferior, and to improve the standards of TCM herbs. This book includes 60 commonly used TCM herbs, each involving the following items: definition, location, action and indication, description, microscopic identification, TLC identification, HPLC/GC fingerprint identification (optional), assay, discussion and references. It is a valuable reference of quality evaluation for TCM herbs."--