[PDF] Progress In The Chemistry Of Organic Natural Products 113 eBook

Author : A Douglas Kinghorn
Publisher : Springer Nature
Page : 247 pages
File Size : 20,78 MB
Release : 2021-04-16
Category : Science
ISBN : 3030530280

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In this book, chemical studies are described mainly from literature reports appearing since 2000, inclusive of investigations performed by the present authors, on the diversity in secondary metabolites of Ligularia growing in the Hengduan Mountains area of China, focusing on eremophilane sesquiterpenoids and other metabolites. More than 100 Ligularia species and their related genera in the plant family Senecioneae plants (Cremanthodium, Cacalia, Senecio, and others) grow in East Asia. For many years, researchers have studied the chemical constituents of these plants, and terpenoids, flavonoids, steroids, alkaloids, and aromatic compounds have been isolated. Among these, in particular, numerous sesquiterpenoids were reported. Within this book terpenoids and aromatic compounds (total 1049), both previously unknown and known, are presented. Finally, genetic studies and synthesis investigations are briefly reviewed.

Author :
Publisher : Springer Science & Business Media
Page : 508 pages
File Size : 48,62 MB
Release : 2012-12-06
Category : Science
ISBN : 3709168872

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The objective of this ASI was to bring together specialists in several complex variables (many of whom have contributed to complex potential theory) and specialists in potential theory (all of whom have contributed to several complex variables) together with young researchers and graduate students for an interchange of ideas and techniques. Not only was the status of current research presented, but also the relevant background, much of which is not yet available in books. The following topics and interconnections among them were discussed: 1. Real and Complex Potential Theory. Capacity and approximation, basic prop erties of plurisubharmonic functions and methods to manipulate their singularities and study their growth, Green functions, Chebyshev-type quadratures, electrostatic fields and potentials, propagation of smallness. 2. Complex Dynamics. Review of complex dynamics in one variable, Julia sets, Fatou sets, background in several variables, Henon maps, ergodicity, use of potential theory and multifunctions. 3. Banach Algebras and Infinite Dimensional Holomorphy. Analytic multi functions, spectral theory, analytic functions on a Banach space, semigroups of holomor phic isometries, Pick interpolation on uniform algebras and Von Neumann inequalities for operators on a Hilbert space. The basic notion of complex potential theory is that of a plurisubharmonic function.

Author : A. Douglas Kinghorn
Publisher : Springer Nature
Page : 183 pages
File Size : 42,52 MB
Release : 2022-04-13
Category : Science
ISBN : 3030920305

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This volume consists of four chapters that cover a structurally diverse range of naturally occurring compounds. Chapter 1 delves into the chemistry of pyrogallols and their oxidized products, the hydroxy-o-quinones, including their role in cycloaddition reactions in the chemical synthesis of several fungal metabolites. Chapter 2 provides an in-depth description of the constituents of agarwood essential oil and smoke samples that are used in the perfumery industry, with an emphasis on the sesquiterpenoid and chromones constituents so far known. Chapter 3 discusses the defensive chemical ecology of two North American newt species that both produce tetrodotoxin, a well-known neurotoxin that causes paralysis and death in metazoans by disrupting electrical signals in the nerves and muscles. Chapter 4 discusses the limonoids and triterpenoids from the genus Walsura of the plant family Meliaceae, of which a number of species are utilized in several southeastern Asian countries in systems of folk medicine.

Author : P. R. Ashurst
Publisher : Springer Science & Business Media
Page : 362 pages
File Size : 18,69 MB
Release : 2012-12-06
Category : Science
ISBN : 370918164X

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Mit Beiträgen zahlreicher Fachwissenschaftler

Author : A. Douglas Kinghorn
Publisher : Springer Science & Business Media
Page : 269 pages
File Size : 38,2 MB
Release : 2011-08-12
Category : Science
ISBN : 3709107482

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The three reviews cover the advances in the chemistry and biology of withanolides over the last 16 years, review the chemistry and biology of the rocaglamide-type derivatives and related compounds, with emphasis on their structural diversity, biosynthesis, pharmacological significance and total synthesis, and summarize the extensive chemistry and biology studies on a natural product, which have resulted in a novel therapy approved worldwide.

Author : A. Douglas Kinghorn
Publisher : Springer Nature
Page : 214 pages
File Size : 45,23 MB
Release : 2021-04-02
Category : Science
ISBN : 3030648532

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This book describes current understandings and recent progress into a varied group of natural products. In the first chapter the role that total synthesis may play in revising the structures proposed for decanolides, which are ten-membered lactones found primarily in fungi, frogs, and termites is presented. The following chapter presents the development of the intriguing plant-derived sesquiterpene lactone, thapsigargin, a potent inhibitor of the enzyme, SERCA (sarco-endoplasmic Ca2+ ATPase), which has potential as a lead compound to treat cancer. The third chapter covers the potential of various plant phenolic compounds for treating the tropical and sub-tropical infectious disease, leishmaniasis. In addition the volume presents recent advances related to the plant alkaloid, cryptolepine, which is of particular interest as a lead for the treatment of malaria, trypanosomiasis, and cancer.

Author : A. Douglas Kinghorn
Publisher : Springer Nature
Page : 455 pages
File Size : 31,56 MB
Release : 2019-10-21
Category : Science
ISBN : 303012858X

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This volume comprises three reviews. The first describes isolation, structure determination, syntheses, and biochemistry of the low molecular weight compounds of the secretion of exocrine glands of termies with emphasis to pheromones and defensive compounds. The second review describes recent studies on isolation and structure elucidation of bioactive compounds involved in the life cycle and determination of the molecular mechanisms of the developmental events observed in higher plants. The third contribution reports on the current body of knowledge of African propolis, with a particular emphasis on its chemistry and biological activity.

Author : A. Douglas Kinghorn
Publisher : Springer
Page : 252 pages
File Size : 35,45 MB
Release : 2017-01-25
Category : Science
ISBN : 3319456180

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The first contribution describes apolar and polar molecular fossils and, in particular biomarkers, along the lines usually followed in organic chemistry textbooks, and points to their bioprecursors when available. Thus, the apolar compounds are divided in linear and branched alkanes followed by alicyclic compounds and aromatic and heterocyclic molecules, and, in particular, the geoporphyrins. The polar molecular fossils contain as functional groups or constituent units ethers, alcohols, phenols, carbonyl groups, flavonoids, quinones, and acids, or are polymers like kerogen, amber, melanin, proteins, or nucleic acids. The final sections discuss the methodology used and the fundamental processes encountered by the biomolecules described, including diagenesis, catagenesis, and metagenesis. The second contribution covers the distribution of phthalides in nature and the findings in the structural diversity, chemical reactivity, biotransformations, syntheses, and bioactivity of natural and semisynthetic phthalides.