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Statistical Methods for QTL Mapping

Author : Zehua Chen
Publisher : CRC Press
Page : 944 pages
File Size : 31,75 MB
Release : 2013-11-01
Category : Mathematics
ISBN : 0415669863

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While numerous advanced statistical approaches have recently been developed for quantitative trait loci (QTL) mapping, the methods are scattered throughout the literature. Statistical Methods for QTL Mapping brings together many recent statistical techniques that address the data complexity of QTL mapping. After introducing basic genetics topics and statistical principles, the author discusses the principles of quantitative genetics, general statistical issues of QTL mapping, commonly used one-dimensional QTL mapping approaches, and multiple interval mapping methods. He then explains how to use a feature selection approach to tackle a QTL mapping problem with dense markers. The book also provides comprehensive coverage of Bayesian models and MCMC algorithms and describes methods for multi-trait QTL mapping and eQTL mapping, including meta-trait methods and multivariate sequential procedures. This book emphasizes the modern statistical methodology for QTL mapping as well as the statistical issues that arise during this process. It gives the necessary biological background for statisticians without training in genetics and, likewise, covers statistical thinking and principles for geneticists. Written primarily for geneticists and statisticians specializing in QTL mapping, the book can also be used as a supplement in graduate courses or for self-study by PhD students working on QTL mapping projects.

Applications of Statistics and Probability in Civil Engineering

Author : Michael Faber
Publisher : CRC Press
Page : 938 pages
File Size : 26,88 MB
Release : 2011-07-15
Category : Technology & Engineering
ISBN : 0203144791

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Under the pressure of harsh environmental conditions and natural hazards, large parts of the world population are struggling to maintain their livelihoods. Population growth, increasing land utilization and shrinking natural resources have led to an increasing demand of improved efficiency of existing technologies and the development of new ones. A

Proceedings

Author : Structural Engineers Association of California. Convention
Publisher :
Page : 360 pages
File Size : 24,82 MB
Release : 1994
Category : Earthquake engineering
ISBN :

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Materials and Joints in Timber Structures

Author : Simon Aicher
Publisher : Springer Science & Business Media
Page : 815 pages
File Size : 21,75 MB
Release : 2013-09-25
Category : Technology & Engineering
ISBN : 9400778112

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This book contains the contributions from the RILEM International Symposium on Materials and Joints in Timber Structures that was held in Stuttgart, Germany from October 8 to 10, 2013. It covers recent developments in the materials and the joints used in modern timber structures. Regarding basic wooden materials, the contributions highlight the widened spectrum of products comprising cross-laminated timber, glulam and LVL from hardwoods and block glued elements. Timber concrete compounds, cement bonded wood composites and innovative light-weight constructions represent increasingly employed alternatives for floors, bridges and facades. With regard to jointing technologies, considerable advances in both mechanical connections and glued joints are presented. Self-tapping screws have created unprecedented options for reliable, strong as well as ductile joints and reinforcement technologies. Regarding adhesives, which constitute the basis of the jointing/laminating technology of modern timber products, extended options for tailor-made bonding solutions have to be stated. Apart from melamine-urea and phenolic-resorcinol adhesives, one-component-polyurethanes, emulsion isocyanate polymers and epoxies offer a wide range of possibilities. The contributions dealing with experimental and numerical investigations on static, cyclic and seismic behavior of structures clearly reveal the enhanced potential of modern timber construction for reliable and sustainable buildings and bridges of the new millennium. The book is structured in nine thematic areas, being I) Structures II) Mechanical Connections III) Glued Joints and Adhesives IV) Timber and Concrete/Cement/Polymer Composites V) Cyclic, Seismic Behavior VI) Hardwood, Modified Wood and Bamboo VII) Cross-Laminated Timber VIII) Properties and Testing of Wood IX) Glulam