[PDF] Organofluorine Compounds In Biology And Medicine eBook

Author : V Prakash Reddy
Publisher : Newnes
Page : 331 pages
File Size : 15,61 MB
Release : 2015-01-25
Category : Science
ISBN : 044453749X

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Organofluorine Compounds in Biology and Medicine covers topics on biochemically relevant organofluorine compounds and their synthesis and biochemical pathways. Organofluorine compounds have renewed interest in pharmaceutical industry, and therefore a concise book on this topic is highly relevant to the scientific community involved in this area. Covers the synthesis, biochemical, and therapeutic applications of organofluorine compounds Offers a complete text on biochemically relevant organofluorine compounds and their synthesis and mechanistic pathways Provides one of the first major reference books on the biological and medicinal applications of organofluorine chemistry

Author : V. Prakash Reddy
Publisher : Elsevier
Page : 360 pages
File Size : 48,88 MB
Release : 2020-03-20
Category : Technology & Engineering
ISBN : 0128132876

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Organofluorine Chemistry: Synthesis and Applications gives a comprehensive outlook on modern synthetic methodologies for organofluorine compounds. It illustrates chemical, biochemical, and materials applications of fluorine-containing compounds, including synthesis and applications of small molecule compounds in drug discovery, positron emission tomography, and fluorinated polymers in solar cells. This book is of use to scientists working in the interdisciplinary areas, such as chemical, biochemical, and biomedical engineering, as well as those involved in materials science and medicinal chemistry. It is also a useful reference for researchers and graduate students interested in organofluorine chemistry. Provides modern synthetic methods and reactions of organofluorine compounds Incorporates the synthesis and chemical, biochemical and biomedical applications of fluorine-containing compounds, nanomaterials, PET imaging agents, pharmaceuticals, and polymeric materials Features emerging "hot" topics, such as late-stage fluorinations and drug discovery

Author : Tamejiro Hiyama
Publisher : Springer Science & Business Media
Page : 281 pages
File Size : 15,72 MB
Release : 2013-03-09
Category : Science
ISBN : 3662041642

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In view of increasing interest in organofluorine compounds, this book was undertaken to describe biological and physical properties of organofluorine compounds, synthetic methods of these, their roles in pharmaceutical, agrochemical and material sciences. In particular, the book will emphasize on the usefulness of fluorination reaction, availability of fluorination agents, so that even graduate students who are unfamiliar to this field can understand and participate in this fascinating heteroatom chemistry.

Author : Robert Filler
Publisher : Elsevier Publishing Company
Page : 408 pages
File Size : 12,2 MB
Release : 1993
Category : Medical
ISBN :

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This text examines the role of fluorine in medicinal chemistry, including anticancer and antiviral agents, and provides up-to-date information on volatile aesthetics and central nervous system agents, areas in which fluorine has played a pivotal role.

Author : Iwao Ojima
Publisher : World Scientific
Page : 842 pages
File Size : 22,35 MB
Release : 2019-12-24
Category : Science
ISBN : 1786347342

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This book focuses on the new frontiers of organofluorine chemistry in synthetic, organometallic, bioorganic, medicinal, agricultural, and materials chemistry as well as chemical physics and their applications to biomedical and material sciences. The extraordinary potential of fluorine-containing molecules in biology, pharmaceuticals, agrochemical, materials and their wide range of applications has been recognized by researchers who are not in the traditional fluorine chemistry field, and thus the new wave of organofluorine chemistry is rapidly expanding its frontiers.Featuring major leading researchers from all over the world and their cutting-edge research projects, this title reviews the recent advances and envision the new exciting developments in the future. Frontiers of Organofluorine Chemistry is an excellent reference book for professional researchers, and graduate students, in both industry and academia to get inspirations and new ideas for their projects.

Author : A.H. Neilson
Publisher : Springer Science & Business Media
Page : 372 pages
File Size : 19,34 MB
Release : 2002-07-03
Category : Medical
ISBN : 9783540420644

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This volume, written by a range of international experts, covers a wide range of topics involving organic fluorine compounds. Each chapter is preceded by a summary and includes extensive illustrations and references. The chapters cover atmospheric chemistry, application of 19F NMR, partition, degradation and transformation, naturally occurring organic fluorine compounds, toxicology of perfluoroalkanes and phosphorofluoridates, and application of aromatic compounds to the elucidation of the mechanism of cytochrome P450.

Author : Kalman J. Szabo
Publisher : John Wiley & Sons
Page : 464 pages
File Size : 44,80 MB
Release : 2021-03-22
Category : Science
ISBN : 3527347119

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By presenting novel methods for the efficient preparation of fluorinated compounds and their application in pharmaceutical and agrochemical chemistry as well as medicine, this is a valuable source of information for all researchers in academia and industry!

Author : Veronique Gouverneur
Publisher : World Scientific
Page : 571 pages
File Size : 37,49 MB
Release : 2012-04-26
Category : Science
ISBN : 1908977892

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Fluorine chemistry is an expanding area of research that is attracting international interest, due to the impact of fluorine in drug discovery and in clinical and molecular imaging (e.g. PET, MRI). Many researchers and academics are entering this area of research, while scientists in industrial and clinical environments are also indirectly exposed to fluorine chemistry through the use of fluorinated compounds for imaging.This book provides an overview of the impact that fluorine has made in the life sciences. In the first section, the emphasis is on how fluorine substitution of amino acids, peptides, nucleobases and carbohydrates can provide invaluable information at a molecular level. The following chapters provide answers to the key questions posed on the importance of fluorine in drug discovery and clinical applications. For examples, the reader will discover how fluorine has found its place as a key element improving drug efficacy, with reference to some of the best-selling drugs on the market. Finally, a thorough review on the design, synthesis and use of 18F-radiotracers for positron emission tomography is provided, and this is complemented with a discussion on how 19F NMR has advanced molecular and clinical imaging./a

Author : J. c. Tatlow
Publisher : Thieme/Houben-Weyl Series
Page : 740 pages
File Size : 36,55 MB
Release : 1998-12-21
Category : Medical
ISBN : 9780865770041

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Organo-fluorine compounds have become increasingly important in the last 50 years, as synthetic routes to them have been developed; very few occur naturally. Their chemical behavior covers the entire range from inertness to high reactivity and their physical properties show unique features. These characteristics have led to many specialist uses in various fields such as inert fluids, polymers, elastomers, surfactants, surface treatment agents, fire extinguishers, biological and medicinal applications, and agriculture. Houben-Weyl Vol. E10 Organo-Fluorine Compounds is a critical survey of the academic and patent literature, organized in a systematic and structured way and presented in 5 volumes. In Volume E10a Section A details the diverse range of fluorinating agents used to make C-F bonds. In Volumes E10b/1 and E10b/2 Section B describes in detail methods for the synthesis of fluorinated compounds from organo-fluorine precursors (the building block approach), while in Section C are outlined general reactions and reactivity of organo-fluorides. A comprehensive index is provided in Volume E10c/1 and E10c/2. Houben-Weyl Vol. E10 Organo-Fluorine Compounds is written by leading experts in the field and will prove to be an invaluable tool for the student and researcher alike well into the next millennium. For full information on the complete Houben-Weyl series, please visit the Houben-Weyl Homepage