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Oecd Guidelines For The Testing Of Chemicals Oecd Series On Testing And Assessment Descriptions Of Selected Key Generic Terms Used In Chemical Hazard Risk Assessment Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Oecd Guidelines For The Testing Of Chemicals Oecd Series On Testing And Assessment Descriptions Of Selected Key Generic Terms Used In Chemical Hazard Risk Assessment book. This book definitely worth reading, it is an incredibly well-written.
Author : OECD
Publisher : OECD Publishing
Page : 92 pages
File Size : 14,64 MB
Release : 2004-11-01
Category :
ISBN : 9264079122
This paper presents internationally harmonised generic and technical terms used in chemical hazard/risk assessment which will help facilitate the mutual use and acceptance of the assessment of chemicals between countries.
Author : OECD
Publisher : OECD Publishing
Page : 170 pages
File Size : 50,90 MB
Release : 2004-11-01
Category :
ISBN : 9264079157
This Detailed Review Paper (DRP) is intended to provide the current state-of-the-knowledge in the area of fish screening assays for chemicals active at the endocrine level on the reproductive system of test animals.
Author : OECD
Publisher : OECD Publishing
Page : 106 pages
File Size : 15,53 MB
Release : 2004-11-01
Category :
ISBN : 9264079149
This Detailed Review Paper (DRP) provides the current state-of-the-knowledge in the area of amphibian metamorphosis with the view to use amphibian metamorphosis as a model for the detection of chemicals affecting the thyroid axis in vertebrates.
Author : Organisation for Economic Co-operation and Development
Publisher : Organisation for Economic Co-operation and Development ; [Montréal : Renouf]
Page : pages
File Size : 32,55 MB
Release : 1981
Category : Chemical industry
ISBN : 9789264122215
Author : OECD
Publisher : OECD Publishing
Page : 99 pages
File Size : 32,31 MB
Release : 2014-09-03
Category :
ISBN : 9264085831
This guidance document provides guidance for assessing the hazards of chemical substances while gaining efficiencies and improving animal welfare. The approach described in this guidance document is to consider closely related chemicals as a group, or category, rather than as individual chemicals.
Author : OECD
Publisher : OECD Publishing
Page : 31 pages
File Size : 15,95 MB
Release : 2004-11-01
Category :
ISBN : 9264078797
This guidance document has been prepared to support technical aspects of the OECD skin absorption test guidelines. In particular is discusses the various aspects of in vivo vs. in vitro testing.
Author : OECD
Publisher : OECD Publishing
Page : 118 pages
File Size : 17,22 MB
Release : 2014-09-03
Category :
ISBN : 9264221484
This document provides guidance on how to use the OECD (Q)SAR Application Toolbox to build chemical categories according to the OECD Guidance on Grouping of Chemicals. It is part of an overall effort to provide guidance on the use of the (Q)SAR Application Toolbox.
Author : OECD
Publisher : OECD Publishing
Page : 66 pages
File Size : 12,8 MB
Release : 2004-11-01
Category :
ISBN : 9264079114
This document contains guidance for using the summary exposure information reporting formats, which were developed by the OECD Ad Hoc Group on Reporting Summary Exposure Information.
Author : John H Duffus
Publisher : Royal Society of Chemistry
Page : 430 pages
File Size : 37,26 MB
Release : 2015-11-09
Category : Science
ISBN : 1782625453
Fundamental Toxicology is a concise and comprehensive review of toxicology. It is based on the highly successful Fundamental Toxicology for Chemists and has been enriched and expanded. Every chapter in this new edition has been revised and updated, and four new chapters have been added. With contributions from internationally recognised experts in their field, this broad-based introduction to the topic covers both well-established and rapidly developing areas of toxicology, such as toxicogenomics, reproductive toxicology, behavioural toxicology and ecotoxicology. The book was written and published with the support of the International Union of Pure and Applied Chemistry (IUPAC). The book includes new information on: risk assessment and risk management; toxicogenomics; effects of toxic substances on the human body; environmental distribution of chemicals and ecotoxicology; clinical toxicology; pharmaceutical toxicology; and aspects of laboratory measurement and safe laboratory practice. Fundamental Toxicology is ideal for students and includes extensive pedagogical features, such as an extensive glossary, a bibliography after each chapter and recommended further reading. It is also designed for teachers and lecturers, especially those who may be teaching toxicology for the first time. Included is a suggested curriculum for using the text to teach toxicology to students from various scientific disciplines. Professionals working in toxicology and related fields will find this an invaluable guide.
Author : Frank A Barile
Publisher : CRC Press
Page : 368 pages
File Size : 31,2 MB
Release : 2013-04-02
Category : Medical
ISBN : 1842145282
Nationally, toxicology programs have evolved from a traditional exploration of the chemistry and applied toxicity of chemicals and drugs to a more comprehensive study of toxicology and toxicology testing as independent entities. Consequently, the second edition of Principles of Toxicology Testing starts with basic toxicological principles, including absorption, distribution, metabolism, and elimination of toxins, including chemicals and drugs. The book then continues with animal (in vivo) and in vitro toxicology testing methods associated with toxicological analysis and preclinical drug development. As in the first edition, the book begins with an introduction into the fundamentals of toxicology (Section I) to prepare readers for the subsequent topics and continues through with a discussion of toxicokinetics and human risk assessment. This introductory material is useful in understanding the applications of toxicology testing. Section II describes the fundamental principles of toxicology testing in animals in greater detail. This section describes acute toxicity studies as well as subchronic and chronic studies performed on animals. Special emphasis is placed on study design and determination of classical indicators for acute and chronic testing, such as the LD50. The book examines other short- and long-term animal toxicity testing methodologies, including dermal, ocular, and reproductive toxicity testing. In addition, mutagenicity and carcinogenicity studies are also discussed in separate chapters. Section III introduces and discusses in vitro alternatives to animal toxicology tests. This section emphasizes cell culture methodology and cellular methods for acute systemic toxicity, target organ toxicity, and local toxicity. The contributors present the advantages and disadvantages of alternative methods. They also describe the use of high-throughput screening and its applications, the concepts of standardization and validation of in vitro techniques (especially large, organized validation efforts currently supported by US and EU regulatory agencies), and the theories supporting the development of in vitro methodologies. This second edition is a must-read for undergraduate and graduate toxicology students. Industrial and academic research centers will also find the text useful for establishing a toxicology testing laboratory.