[PDF] New Frontiers In Pediatric Drug Therapy eBook

Author : Jacob V. Aranda
Publisher : Elsevier Health Sciences
Page : pages
File Size : 32,97 MB
Release : 2017-12-01
Category : Medical
ISBN : 0323552919

GET BOOK

Dr. Aranda is an top expert in the area of pharmacology in the pediatric population. His issue has knowledgeable authors presenting clinical reviews on a wide variety of topics, from "hot areas " of drug therapy to drug abuse in children as well as current areas of debate in neonatal drug therapy. Articles are devoted to the following topics: New and Current Drug Therapies For Asthma In Children; Psychopharmacology Of Bipolar Disorders in Children and Adolescents; Designer Drug Abuse in School Children; Dietary Supplements in Children; Anticoagulant Therapies in Children; New Antimicrobials for Gram-Positive Infections in Children; Probiotics in Newborns And Children; Anticonvulsant Therapies in Newborns and Children; Immunomodulator Drug Therapies in Inflammatory Bowel Diseases in Children; Non-Steroidal Anti-Inflammatory Drugs in Newborns and Children; Metformin Use in Pre-Diabetic Children and Adolescents; Problems in Drug Dosing of Obese Children; Inhaled Drugs and Systemic Steroids for Bronchopulmonary Dysplasia; Antifungal Drugs in Newborns and Children; Antiviral Drugs In Newborns and Children; and Development of Drug Therapies for Newborns and Children. Readers will come away with the latest clinical information to help inform them when diagnosing and prescribing for children.

Author : Vishwanath Gaitonde
Publisher : BoD – Books on Demand
Page : 166 pages
File Size : 15,22 MB
Release : 2020-03-11
Category : Medical
ISBN : 1789239753

GET BOOK

The process of drug discovery and development is a complex multistage logistics project spanned over 10-15 years with an average budget exceeding 1 billion USD. Starting with target identification and synthesizing anywhere between 10k to 15k synthetic compounds to potentially obtain the final drug that reaches the market involves a complicated maze with multiple inter- and intra-operative fields. Topics described in this book emphasize the progresses in computational applications, pharmacokinetics advances, and molecular modeling developments. In addition the book also contains special topics describing target deorphaning in Mycobacterium tuberculosis, therapy treatment of some rare diseases, and developments in the pediatric drug discovery process.

Author : Louis A. Pagliaro
Publisher : Washington, D.C. : American Pharmaceutical Association
Page : 862 pages
File Size : 22,73 MB
Release : 2002
Category : Medical
ISBN :

GET BOOK

Written for all pediatric clinicians and students, Problems in Pediatric Drug Therapy is an authoritative, well-referenced, and accessible source of essential information on the use and effects of drugs in infants and children. Twenty widely published clinicians, educators, and researchers from pharmacy, medicine, and nursing have authored 14 chapters, each dealing with a major, potentially problematic area of pediatric drug therapy. Building on the well-received previous editions -- the third edition was named an American Journal of Nursing Book of the Year in the category of pediatric nursing -- the fourth edition focuses on the key concerns in pediatric drug therapy today: drug administration, pharmacokinetics, drugs as teratogens and fetotoxins, excretion of drugs into breast milk, pediatric poisoning, adverse reactions, drug interactions, drug abuse, IV drugs, and immunizations. Two new chapters cover the increasingly important areas of pediatric antineoplastic therapy and pharmacogenetics. The concluding two hallmark chapters on dosing in neonates and in infants, children, and adolescents, respectively, have been expanded and updated to reflect current trends in drug use.

Author : Donato Bonifazi
Publisher :
Page : pages
File Size : 45,82 MB
Release : 2020
Category :
ISBN :

GET BOOK

Drug discovery and development advances in the last decades allowed to find a treatment for many preventable diseases. However, all too often, children are excluded from these progresses since most of the new medicines have been discovered and developed for the adult population. Even if paediatricians routinely give drugs to children 'off-label', researchers have demonstrated that children do not respond to medications in the same way as adults. Furthermore, certain specific disorders are unique to children or occur in children differently than in adults. Besides specifically testing medicines in children in proper clinical studies taking into due account the peculiarity of this population, there is a growing recognition of the need to develop paediatric medicines having in mind the specificities of this vulnerable population. In this chapter, we will provide an overview on the drug discovery and development path for children highlighting challenges and new frontiers of each phase from the discovery to the preclinical and clinical development as well as we will provide a slightest hint about paediatric biomarkers discovery, age-appropriate formulation, pregnancy, and perinatal pharmacology and in silico pharmacology. Finally, pricing and reimbursement policies for medicines and new and existing research initiatives in the field will be discussed.

Author : Donato Bonifazi
Publisher :
Page : 0 pages
File Size : 25,67 MB
Release : 2020
Category : Medical
ISBN :

GET BOOK

Drug discovery and development advances in the last decades allowed to find a treatment for many preventable diseases. However, all too often, children are excluded from these progresses since most of the new medicines have been discovered and developed for the adult population. Even if paediatricians routinely give drugs to children ,Äòoff-label,Äô, researchers have demonstrated that children do not respond to medications in the same way as adults. Furthermore, certain specific disorders are unique to children or occur in children differently than in adults. Besides specifically testing medicines in children in proper clinical studies taking into due account the peculiarity of this population, there is a growing recognition of the need to develop paediatric medicines having in mind the specificities of this vulnerable population. In this chapter, we will provide an overview on the drug discovery and development path for children highlighting challenges and new frontiers of each phase from the discovery to the preclinical and clinical development as well as we will provide a slightest hint about paediatric biomarkers discovery, age-appropriate formulation, pregnancy, and perinatal pharmacology and in silico pharmacology. Finally, pricing and reimbursement policies for medicines and new and existing research initiatives in the field will be discussed.

Author : Jacob V. Aranda
Publisher : Lippincott Williams & Wilkins
Page : 2499 pages
File Size : 13,52 MB
Release : 2020-11-05
Category : Medical
ISBN : 1975112490

GET BOOK

The premier comprehensive textbook in the field, Yaffe and Aranda’s Neonatal and Pediatric Pharmacology, Fifth Edition, provides an authoritative overview of all aspects of drug therapy in newborns, children, and adolescents. It offers evidence-based guidelines for safe, effective, and rational drug therapy, including specific recommendations for all major drug classes and diseases. Now in a vibrant two-color format, this fully revised reference is an indispensable resource for pediatricians, neonatologists, pediatric residents, and fellows in different pediatric subspecialties, including neonatal medicine and pediatric critical care.