[PDF] Mkenna And Chapman V Tripletts Administrator 1824 eBook

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Page : 15 pages
File Size : 30,24 MB
Release : 1824
Category : Law
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File No. 1277

Author : Karl Bechter
Publisher : Frontiers Media SA
Page : 189 pages
File Size : 35,45 MB
Release : 2019-08-12
Category :
ISBN : 2889459500

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Growing evidence derived from cerebrospinal fluid (CSF), neuropathological, imaging, genetic, and epidemiological studies link neuroinflammation and immune dysregulation to a subset of individuals with a variety of severe mental disorders (SMDs), including affective and non-affective psychotic disorders. Further, the recent discoveries of neuronal surface antibodies (NSAs) in autoimmune encephalitis (AE) presenting with diverse neuropsychiatric disorders such as psychosis and cognitive decline, among many others, provides further support to the notion that CNS autoimmunity and neuroinflammation can contribute to the neurobiology of psychiatric disturbances. Further, these immune mechanisms may contribute to a subset of patients currently diagnosed as having treatment-resistant SMDs such as schizophrenia and major depressive disorder. Additionally, mounting data indicate that various infections can serve as an immunological trigger of aberrant immune responses, presumably by causing release of excess neural antigen, thereby giving rise to NSAs or aberrant immune cellular responses to give rise to primary or secondary psychiatric disorders such as schizophrenia and those associated with AE, respectively. Collectively, these findings support the “mild encephalitis” hypothesis of SMD. The significant overlap among AE-associated psychosis, systemic autoimmune disorder-associated psychosis, and psychotic disorders associated with pathological processes involving inflammation and immune dysregulation has also prompted some authors to adopt the term “autoimmune psychosis” (AP). This term reflects that this psychosis subtype is mechanistically linked to complex neuroimmune and inflammatory signalling abnormalities that can be responsive to early immunomodulatory treatment. It also suggests that a subset of AP might represent an incomplete or “forme fruste” subtype of AE presenting with dominant or pure psychiatric symptoms mimicking primary psychiatric illnesses. Because data indicate that delayed diagnosis and treatment may lead to permanent sequelae, early recognition of AP utilizing neurodiagnostic workup (e.g., CSF analysis, neuroimaging, and EEG) and its early treatment with appropriate immunotherapy are paramount to a meaningful recovery. This eBook will provide an overview of the current knowledge and research areas from epidemiology, risk factors and diagnosis to the management of these conditions, in this rapidly emerging field, helping to bridge the gaps in knowledge that currently exist in the disciplines of Psychiatry, Neurology, and Neuroimmunology.

Author : David Latchman
Publisher : Garland Science
Page : 405 pages
File Size : 24,36 MB
Release : 2007-01-25
Category : Medical
ISBN : 0203016335

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Gene regulation is an essential process in the development and maintenance of a healthy body, and as such, is a central focus in both basic science and medical research. Gene Regulation, Fifth Edition provides the student and researcher with a clear, up-to-date description of gene regulation in eukaryotes, distilling the vast and complex primary literature into a concise overview.

Author : Hanna K. Gaggin
Publisher : Springer Science & Business Media
Page : 660 pages
File Size : 35,72 MB
Release : 2013-08-26
Category : Medical
ISBN : 144714483X

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MGH Cardiology Board Review is intended for physicians studying for the Cardiology Board Examination (Initial Certification or Re-certification) and for any busy practitioners who would like to review high-yield cardiology such as those in cardiology, emergency medicine, internal medicine, family practice, or even surgery. Designed for those on the go, each section is meant to be completed in 30 minutes; and at 30 minutes a day, the reader will have a complete overview of up-to-date information in 30 days. Each section has a concise didactic followed by a questions section with an identical format to the Cardiovascular Board Examination of the American Board of Internal Medicine.This book is from the Massachusetts General Hospital’s Cardiology Division, one of the most respected cardiology programs in the world and is its first Cardiology review book.

Author : Lei Xi
Publisher : Springer Science & Business Media
Page : 310 pages
File Size : 12,54 MB
Release : 2012-06-05
Category : Medical
ISBN : 1447129067

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Intermittent hypoxia can cause significant structural and functional impact on the systemic, organic, cellular and molecular processes of human physiology and pathophysiology. This book focuses on the most updated scientific understanding of the adaptive (beneficial) and maladaptive (detrimental) responses to intermittent hypoxia and their potential pathogenetic or prophylactic roles in the development and progression of major human diseases. This is a comprehensive monograph for clinicians, research scientists, academic faculty, postgraduate and medical students, and allied health professionals who are interested in enhancing their up-to-date knowledge of intermittent hypoxia research and its translational applications in preventing and treating major human diseases.

Author : Srinivasan Damodaran
Publisher : CRC Press
Page : 1107 pages
File Size : 48,1 MB
Release : 2017-05-25
Category : Medical
ISBN : 148220813X

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This latest edition of the most internationally respected reference in food chemistry for more than 30 years, Fennema’s Food Chemistry, 5th Edition once again meets and surpasses the standards of quality and comprehensive information set by its predecessors. All chapters reflect recent scientific advances and, where appropriate, have expanded and evolved their focus to provide readers with the current state-of-the-science of chemistry for the food industry. This edition introduces new editors and contributors who are recognized experts in their fields. The fifth edition presents a completely rewritten chapter on Water and Ice, written in an easy-to-understand manner suitable for professionals as well as undergraduates. In addition, ten former chapters have been completely revised and updated, two of which receive extensive attention in the new edition including Carbohydrates (Chapter 3), which has been expanded to include a section on Maillard reaction; and Dispersed Systems: Basic considerations (Chapter 7), which includes thermodynamic incompatibility/phase separation concepts. Retaining the straightforward organization and accessibility of the original, this edition begins with an examination of major food components such as water, carbohydrates, lipids, proteins, and enzymes. The second section looks at minor food components including vitamins and minerals, colorants, flavors, and additives. The final section considers food systems by reviewing basic considerations as well as specific information on the characteristics of milk, the postmortem physiology of edible muscle, and postharvest physiology of plant tissues.