[PDF] Microfabricated Cortical Neuroprostheses eBook

Author : Andre Mercanzini
Publisher : CRC Press
Page : 144 pages
File Size : 41,62 MB
Release : 2011-01-14
Category : Medical
ISBN : 1482247151

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Despite their demonstrated effectiveness, the long term use of microscale neuroprosthetic devices is compromised by the post-implantation tissue reaction that often forms around the device. This book studies ways to improve the tissue reaction to implanted neuroprosthesis by use of a controlled drug release mechanism, quantified by novel measurement techniques. The author describes solutions to the problem of tissue reaction around microscale neuroprostheses and an also examines an improvement in neural stimulation and recording capability. The author, Andre Mercanzini is Review Editor for Frontiers in Neuroengineering. He holds two U.S. patents on microassembly.

Author : Matthew E. Gladden
Publisher : Synthypnion Academic
Page : 312 pages
File Size : 39,56 MB
Release : 2017-05-13
Category : Business & Economics
ISBN : 194437308X

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This volume serves a resource for the design and analysis of neuroprosthetic supersystems, which can be defined as organizations – either small or large, simple or complex – whose human members have been neuroprosthetically augmented. While numerous other texts focus on the biomedical engineering of neuroprostheses as technological devices or on the biocybernetic engineering of the host-device system comprising a neuroprosthesis and its human host, this volume presents a unique investigation of the intentional creation of higher-order supersystems that allow multiple neuroprosthetically augmented human beings to interact with one another and with external information systems in order to accomplish some shared task. In essence, this can be understood as the work of designing and managing neuroprosthetically enhanced organizations. Individual chapters present an ontology of the neuroprosthesis as a computing device; a biocybernetic ontology of the host-device system; an ontology of the neuroprosthesis as an instrument of ‘cyborgization’; motivating and inhibiting factors for the organizational deployment of posthumanizing neuroprostheses by military organizations and other early adopters; an introduction to enterprise architecture in the context of technological posthumanization; an exploration of the implications of neuroprosthetic augmentation for enterprise architecture; and considerations for the development of effective network topologies for neuroprosthetically augmented organizations. The conceptual frameworks formulated within this book offer a wide range of tools that can be of use to policymakers, ethicists, neuroprosthetic device manufacturers, organizational decision-makers, and others who must analyze or manage the complex legal, ethical, and managerial implications that result from the use of emerging neuroprosthetic technologies within an organizational context.

Author : Timothée Levi
Publisher : Frontiers Media SA
Page : 326 pages
File Size : 37,98 MB
Release : 2018-04-26
Category :
ISBN : 2889454665

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Millions of people worldwide are affected by neurological disorders which disrupt the connections within the brain and between brain and body causing impairments of primary functions and paralysis. Such a number is likely to increase in the next years and current assistive technology is yet limited. A possible response to such disabilities, offered by the neuroscience community, is given by Brain-Machine Interfaces (BMIs) and neuroprostheses. The latter field of research is highly multidisciplinary, since it involves very different and disperse scientific communities, making it fundamental to create connections and to join research efforts. Indeed, the design and development of neuroprosthetic devices span/involve different research topics such as: interfacing of neural systems at different levels of architectural complexity (from in vitro neuronal ensembles to human brain), bio-artificial interfaces for stimulation (e.g. micro-stimulation, DBS: Deep Brain Stimulation) and recording (e.g. EMG: Electromyography, EEG: Electroencephalography, LFP: Local Field Potential), innovative signal processing tools for coding and decoding of neural activity, biomimetic artificial Spiking Neural Networks (SNN) and neural network modeling. In order to develop functional communication with the nervous system and to create a new generation of neuroprostheses, the study of closed-loop systems is mandatory. It has been widely recognized that closed-loop neuroprosthetic systems achieve more favorable outcomes for users then equivalent open-loop devices. Improvements in task performance, usability, and embodiment have all been reported in systems utilizing some form of feedback. The bi-directional communication between living neurons and artificial devices is the main final goal of those studies. However, closed-loop systems are still uncommon in the literature, mostly due to requirement of multidisciplinary effort. Therefore, through eBook on closed-loop systems for next-generation neuroprostheses, we encourage an active discussion among neurobiologists, electrophysiologists, bioengineers, computational neuroscientists and neuromorphic engineers. This eBook aims to facilitate this process by ordering the 25 contributions of this research in which we highlighted in three different parts: (A) Optimization of different blocks composing the closed-loop system, (B) Systems for neuromodulation based on DBS, EMG and SNN and (C) Closed-loop BMIs for rehabilitation.

Author : Andrej Kral
Publisher : Academic Press
Page : 414 pages
File Size : 48,25 MB
Release : 2021-04-03
Category : Technology & Engineering
ISBN : 0128188936

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Prostheses for the Brain: Introduction to Neuroprosthetics bridges the disciplines required in the field of neuroprosthetics and provides the interdisciplinary base required for understanding neuroprosthetic devices. It introduces basic aspects from the physical, bioengineering and medical perspectives, and forms a common knowledge base. It provides the entrance to the field and sets realistic expectations, both regarding potentials as well as limitations, for the devices in both design and outcomes. The book additionally reviews the technology behind the most frequently used and most clinically successful neuroprosthetic devices. It provides the physiological background for their function, as well as the technology behind them. Finally, the authors suggest future possible developments that may play crucial role in new prostheses for the brain. This gives the reader a comprehensive view on the principles and applications of neuroprostheses. This book has been built from the authors course they teach on neuroprostheses and is ideal for students, engineers and medical professionals in this field. Introduces the general principles of conductivity of electrolytes and the processes at the tissue–electrode interface Describes safety issues and regulatory rules, clarifies conceptual differences between stimulating and sensing electrodes Reviews stimulation strategies, tissue reactions, potential medical complications, brain adaptations and the clinically most successful applications of neuroprostheses

Author :
Publisher : ScholarlyEditions
Page : 8760 pages
File Size : 21,40 MB
Release : 2012-01-09
Category : Technology & Engineering
ISBN : 1464920583

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Advances in Nanotechnology Research and Application: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Nanotechnology. The editors have built Advances in Nanotechnology Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Nanotechnology in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Nanotechnology Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Author : Kenneth W. Horch
Publisher : World Scientific
Page : 1292 pages
File Size : 36,94 MB
Release : 2004
Category : Science
ISBN : 9789812380227

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A study of neuroprosthetics. It is broadly divided into three sections which address: neuroanatomy and neurophysiology, biomaterials and biocompatibility, stimulation and recording techniques; clinical applications of neuroprosthetics; and future developments.

Author : Kenneth W Horch
Publisher : World Scientific
Page : 934 pages
File Size : 18,66 MB
Release : 2017-03-10
Category : Technology & Engineering
ISBN : 9813207167

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This is an updated and abridged edition of the original volume published in 2004. Like its predecessor it is targeted for students of bioengineering, biomedical engineering, applied physiology, biological cybernetics and related fields; for engineers and scientists who have an interest in neuroprosthetics; and for medical practitioners using products of that field.The practice of neuroprosthetics requires a fundamental understanding of the anatomy and physiology of the nervous system, mathematical neurobiology, material science, electrochemistry, and electrophysiology. The text assumes some familiarity with basic anatomy, physiology, calculus, electrophysiology and bioinstrumentation, which typically are covered in undergraduate and first year graduate bioengineering curricula. These areas are also reviewed here, with the aim of consolidating principles fundamental to understanding the field. With that as background, the book then presents an overview of the field with detailed emphasis in selected areas of neural interfaces and neuroprostheses. The covered topics provide readers with sufficient information to understand the theory, rationale, design, and functioning of neuroprosthetic devices currently in clinical use and under development.The current volume is shorter than its predecessor. This has been achieved by reducing some of the repetition present in certain chapters of the earlier edition and eliminating a few chapters whose topics are now well covered in review literature readily available on the internet and elsewhere. Two chapters have been retained in their original versions to provide important background material, but the remaining chapters have either been revised by their original authors or replaced by new versions written by different authors. In addition new topics have been added to the section on existing systems.

Author : Maria Rosa Aguilar
Publisher : Woodhead Publishing
Page : 650 pages
File Size : 46,44 MB
Release : 2019-02-15
Category : Technology & Engineering
ISBN : 0081024177

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Smart Polymers and Their Applications, Second Edition presents an up-to-date resource of information on the synthesis and properties of different types of smart polymers, including temperature, pH, electro, magnetic and photo-responsive polymers, amongst others. It is an ideal introduction to this field, as well as a review of the latest research in this area. Shape memory polymers, smart polymer hydrogels, and self-healing polymer systems are also explored. In addition, a very strong focus on applications of smart polymers is included for tissue engineering, smart polymer nanocarriers for drug delivery, and the use of smart polymers in medical devices. Additionally, the book covers the use of smart polymers for textile applications, packaging, energy storage, optical data storage, environmental protection, and more. This book is an ideal, technical resource for chemists, chemical engineers, materials scientists, mechanical engineers and other professionals in a range of industries. Includes a significant number of new chapters on smart polymer materials development, as well as new applications development in energy storage, sensors and devices, and environmental protection Provides a multidisciplinary approach to the development of responsive polymers, approaching the subject by the different types of polymer (e.g. temperature-responsive) and its range of applications

Author : Thomas D. Coates,Jr.
Publisher : Springer Nature
Page : 107 pages
File Size : 21,49 MB
Release : 2022-05-31
Category : Technology & Engineering
ISBN : 3031016408

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In the past 50 years there has been an explosion of interest in the development of technologies whose end goal is to connect the human brain and/or nervous system directly to computers. Once the subject of science fiction, the technologies necessary to accomplish this goal are rapidly becoming reality. In laboratories around the globe, research is being undertaken to restore function to the physically disabled, to replace areas of the brain damaged by disease or trauma and to augment human abilities. Building neural interfaces and neuro-prosthetics relies on a diverse array of disciplines such as neuroscience, engineering, medicine and microfabrication just to name a few. This book presents a short history of neural interfacing (N.I.) research and introduces the reader to some of the current efforts to develop neural prostheses. The book is intended as an introduction for the college freshman or others wishing to learn more about the field. A resource guide is included for students along with a list of laboratories conducting N.I. research and universities with N.I. related tracks of study. Table of Contents: Neural Interfaces Past and Present / Current Neuroprosthesis Research / Conclusion / Resources for Students