[PDF] Microextraction Techniques eBook

Author : M. Valcárcel
Publisher : Bentham Science Publishers
Page : 430 pages
File Size : 45,40 MB
Release : 2017-01-13
Category : Science
ISBN : 1681083795

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Sample treatment has been the focus of intensive research in the last 20 years since it still remains a bottleneck in precise analytical procedures. The low concentration of the target analytes, the large amount of potential interfering agents and the incompatibility of the sample matrix with the instrumental techniques are the main reasons for these bottlenecks. In most of these methods, sample treatment is an unavoidable step and it has a clear influence on the quality (sensitivity, selectivity, and accuracy) of the final analytical results. While the usefulness of microextraction techniques has been established, their complete acceptance in analytical laboratories (including official methods of analysis) depends on their successful automation and integration with conventional analytical instrumentation. Analytical Microextraction Techniques presents comprehensive information about several analytical methods that are useful in the laboratory. These include: sorptive microextraction, solid and liquid phase microextraction, packed sorbent microextraction, miniaturized dispersive solid-phase extraction, thin film and nanoparticle based techniques, and membrane-based techniques. This is a vital reference on microextraction and sample preparation techniques for applied chemistry students, analytical chemists and laboratory technicians.

Author : Janusz Pawliszyn
Publisher : Elsevier
Page : 497 pages
File Size : 50,28 MB
Release : 2011-12-01
Category : Science
ISBN : 0123914493

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The relatively new technique of solid phase microextraction (SPME) is an important tool to prepare samples both in the lab and on-site. SPME is a "green" technology because it eliminates organic solvents from analytical laboratory and can be used in environmental, food and fragrance, and forensic and drug analysis. This handbook offers a thorough background of the theory and practical implementation of SPME. SPME protocols are presented outlining each stage of the method and providing useful tips and potential pitfalls. In addition, devices and fiber coatings, automated SPME systems, SPME method development, and In Vivo applications are discussed. This handbook is essential for its discussion of the latest SPME developments as well as its in depth information on the history, theory, and practical application of the method. Practical application of Solid Phase Microextraction methods including detailed steps Provides history of extraction methods to better understand the process Suitable for all levels, from beginning student to experienced practitioner

Author : John M Kokosa
Publisher : John Wiley & Sons
Page : 340 pages
File Size : 19,32 MB
Release : 2009-10-05
Category : Science
ISBN : 0470278595

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This book offers both a practical as well a theoretical approach to Solvent Microextraction (SME) and will help analytical chemists to evaluate SME for a given sample preparation. Introductory chapters overview a comparison of SME with other sample preparation methods, a summary of the technical aspects, and a detailed theoretical treatment of SME. The book then describes the practical aspects of the technique, with detailed “how to” chapters devoted to the preparation and analysis of atmospheric, solid and liquid environmental, clinical and industrial samples. This text will serve as both a handy laboratory desk-reference and an indispensible instructional tool.

Author : Wenkui Li
Publisher : John Wiley & Sons
Page : 384 pages
File Size : 22,58 MB
Release : 2019-03-12
Category : Science
ISBN : 111927429X

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Revised and Expanded Handbook Provides Comprehensive Introduction and Complete Instruction for Sample Preparation in Vital Category of Bioanalysis Following in the footsteps of the previously published Handbook of LC-MS Bioanalysis, this book is a thorough and timely guide to all important sample preparation techniques used for quantitative Liquid Chromatography–Mass Spectrometry (LC-MS) bioanalysis of small and large molecules. LC-MS bioanalysis is a key element of pharmaceutical research and development, post-approval therapeutic drug monitoring, and many other studies used in human healthcare. While advances are continually being made in key aspects of LC-MS bioanalysis such as sensitivity and throughput, the value of research/study mentioned above is still heavily dependent on the availability of high-quality data, for which sample preparation plays the critical role. Thus, this text provides researchers in industry, academia, and regulatory agencies with detailed sample preparation techniques and step-by-step protocols on proper extraction of various analyte(s) of interest from biological samples for LC-MS quantification, in accordance with current health authority regulations and industry best practices. The three sections of the book with a total of 26 chapters cover topics that include: Current basic sample preparation techniques (e.g., protein precipitation, liquid-liquid extraction, solid-phase extraction, salting-out assisted liquid-liquid extraction, ultracentrifugation and ultrafiltration, microsampling, sample extraction via electromembranes) Sample preparation techniques for uncommon biological matrices (e.g., tissues, hair, skin, nails, bones, mononuclear cells, cerebrospinal fluid, aqueous humor) Crucial aspects of LC-MS bioanalytical method development (e.g., pre-analytical considerations, derivation strategies, stability, non-specific binding) in addition to sample preparation techniques for challenging molecules (e.g., lipids, peptides, proteins, oligonucleotides, antibody-drug conjugates) Sample Preparation in LC-MS Bioanalysis will prove a practical and highly valuable addition to the reference shelves of scientists and related professionals in a variety of fields, including pharmaceutical and biomedical research, mass spectrometry, and analytical chemistry, as well as practitioners in clinical pharmacology, toxicology, and therapeutic drug monitoring.

Author : Rajeev Jain
Publisher : CRC Press
Page : 268 pages
File Size : 34,39 MB
Release : 2021-12-31
Category : Science
ISBN : 1000473740

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Microextraction Techniques in Analytical Toxicology provides the information readers need to include about cutting-edge sample preparation techniques into their everyday analytical practice, including comprehensive information about principles and state-of-the-art microextraction sample preparation techniques for the analysis of drugs and poisons in biological specimens, especially in forensic and clinical settings. This book also focuses on theoretical discussions of solid-based and liquid-based microextraction techniques, their method development, validation, and applications. A detailed compilation of analytical protocols based on published microextraction procedures to aid in method development, synthesis, and the application of green solvents (ionic liquids and deep eutectic solvents) and new sorbents, such as molecularly imprinted polymers, and their application in microextraction techniques are also covered. Features: Provides a systematic review of microextraction techniques applied in analytical toxicology A comprehensive guide for the practical implementation of microextraction techniques in forensic, clinical, and analytical laboratories Contains figures and tables for easy understanding and quick adaptation of the parameters of microextraction techniques Fundamentals, development, and applications of microextraction techniques as a sample preparation procedure are discussed in detail Extremely useful for the researchers and academicians engaged in analytical method development using microextraction techniques This book appeals to a wide readership of forensic, clinical, and analytical toxicologists, as well as academicians and researchers. Written by eminent scientists and leading experts on sample preparation techniques, this book serves as a desk reference for routine laboratory analysis and as an indispensable teaching tool in the classroom for graduate and Ph.D. students.

Author : John R. Dean
Publisher : John Wiley & Sons
Page : 308 pages
File Size : 49,58 MB
Release : 2010-05-18
Category : Science
ISBN : 9780470682500

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This book coves one of the most important areas in analytical sciences, extraction techniques for organic compounds in environmental and related matrices. This text discusses all of the key stages for analysing a sample for organic compounds from the initial sampling protocols, the range of different extraction techniques for solid, liquid and air samples through to the final chromatographic analysis. The topics covered include: Initial steps for solid, aqueous and air sampling. Extraction techniques for aqueous samples, including LLE, purge and trap, SPE, SPME, SBSE, SDME, membrane microextraction and MPES. Extraction techniques for solid samples, including Soxhlet, 'Soxtec', Shake-flask, sonication, PFE, MAE, SFE and MSPD. Extraction techniques for air sampling, including whole air, enrichment approaches and desorption techniques. Pre-concentration approaches for post-extraction. Practical aspects for chromatographic analysis (GC and HPLC) of organic compounds. Quality assurance aspects of analysis. Health and safety considerations. Key features include: Up-to-date information on the latest development in extraction techniques for organic compounds in environmental and food matrices. Ideal for use as a self-study guide, as the basis of a taught course or guided reading for new 'early-career' researchers. Includes a guide for the reader to other sources of information. Extraction Techniques in Analytical Sciences is suitable for undergraduate and postgraduate students, as well as providing an invaluable starting point for individuals undertaking applied research in the fields of analytical, bioanalytical, environmental and food sciences. The Analytical Techniques in the Sciences series of books provides coverage of all of the major analytical techniques and their application in the most important areas of physical, life and materials science. Each text is presented in an open learning/distance learning style, in which the learning objectives are clearly identified. the reader's understanding of the material is constantly evaluated by the use of self-assessment and discussion questions.

Author : Marcello Locatelli
Publisher : MDPI
Page : 308 pages
File Size : 36,45 MB
Release : 2019-06-24
Category : Technology & Engineering
ISBN : 303921084X

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The present Special Issue, “Innovative Extraction Techniques and Hyphenated Instrument Configuration for Complex Matrices Analysis”, aims to collect and to disseminate some of the most significant and recent contributions in the interdisciplinary area of innovative extraction procedures from complex matrices followed by validated analytical methods using hyphenated instrument configurations to support the optimization of the whole process and the scale-up possibility

Author : Janusz Pawliszyn
Publisher : John Wiley & Sons
Page : 266 pages
File Size : 18,34 MB
Release : 1997-04-21
Category : Science
ISBN : 9780471190349

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Gesetzliche Auflagen und ökonomische Erwägungen steigern den Bedarf an Propenpräparations- und -extraktionstechniken, die ohne toxische organische Lösungsmittel auskommen. Die hier erstmals in Buchform veröffentlichte Festphasen-Mikroextraktion (SPME) ist ein neuartiges Verfahren, das diesen Anforderungen entspricht und gegenwärtig apparativ umgesetzt wird. Der Erfinder selbst, ein international anerkannter Pionier auf dem Gebiet der lösungsmittelfreien Extraktion, erklärt theoretische Hintergründe und praktische Anwendungsmöglichkeiten. SPME ist einfach, kostengünstig, automatisierbar, zeit- und analytsparend. Interessant für Analytiker in Industrie und Forschung, für Spurenanalytik, Umwelt- und pharmazeutische Chemie.

Author : John R. Dean
Publisher : John Wiley & Sons
Page : 266 pages
File Size : 26,1 MB
Release : 2022-03-01
Category : Science
ISBN : 1119719046

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Extraction Techniques for Environmental Analysis Explore the analytical approach to extraction techniques In Extraction Techniques for Environmental Analysis, accomplished environmental scientist and researcher John R. Dean delivers a comprehensive discussion of the extraction techniques used for organic compounds relevant to environmental analysis. In the book, extraction techniques for aqueous, air, and solid environmental matrices are explored and case studies that highlight those techniques are included. Readers will find in-depth treatments of specific extraction techniques suitable for adoption in their own laboratories, as well as reviews of relevant analytical techniques used for the analysis of organic compound extracts (with a focus on chromatographic separation and detection). Extraction Techniques for Environmental Analysis also includes a chapter that extensively covers the requirements for an analytical laboratory, including health and safety standards, as well as: A thorough introduction to pre-sampling, as well as the extraction of aqueous samples, including the classical approach for aqueous extraction and solid phase extraction Comprehensive explorations of the extraction of gaseous samples, including air sampling Practical discussions of the extraction of solid samples, including pressurized fluid extraction and microwave-assisted extraction In-depth examinations of post-extraction procedures, including pre-concentration using solvent evaporation Extraction Techniques for Environmental Analysis is a must-read resource for undergraduate students of applied chemistry, as well as postgraduates taking analytical chemistry courses or courses in related disciplines, like forensic or environmental science.

Author : Janusz Pawliszyn
Publisher : Royal Society of Chemistry
Page : 663 pages
File Size : 37,2 MB
Release : 2023-03-24
Category : Science
ISBN : 1839166800

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Solid Phase Microextraction (SPME) is a flexible and convenient sampling and sample preparation technique that extracts different kinds of analytes, including both volatile and non-volatile, without the use of a solvent. The technique facilitates fast, simple and automated determination of target analytes in a range of matrices. As it offers a green methodology, it is growing in popularity as an alternative tool in analytical chemistry to traditional methods. This book follows on in spirit from the editors' previous title, Applications of Solid Phase Microextraction and will introduce the reader to breakthrough methodologies and cutting edge applications. Although it assumes a good degree of SPME knowledge, an overview of the fundamentals is given before taking the reader through an update of the field. The reader will learn the basic principles and advantages of different SPME formats including the stir bar extraction techniques, thin film SPME, Bio-SPME, and new trends in different coatings. Applications in complex media, including food analysis, drug residues and bioanalysis are covered. Bringing together leading sample preparation academics from around the world, the editor has put together an informative new book, suitable for analytical chemists and practitioners utilising SPME tools in their research.