[PDF] Microencapsulation And Artificial Cells eBook

Author : Jan E. Vandegaer
Publisher : Springer Science & Business Media
Page : 183 pages
File Size : 36,61 MB
Release : 2012-12-06
Category : Medical
ISBN : 1468407392

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of McGill University of Montreal, Canada, who talks about artifi cial cells prepared from semipermeable microcapsules. Also illustrative of this method is a contribution on microencapsulated pesticides by C. B. Desavigny and E. E. Ivy of Pennwalt Corporation. Another method of polymerization in situ is micro encapsulation by vapor deposition, the subject of W. M. Jayne of Union Carbide Corporation. The more mechanical methods of microencapsulation are represented by two techniques, one involving a fluidized bed the other involving mainly a centrifugal method. The fluidized bed method is covered in a paper by H. Hall and T. M. Hinkes of the Wisconsin Alumini Research Foundation. The centrifugal and other related methods are treated by Mr. J. E. Goodwin and Mr. Sommerville of the Southwest Research Institute of San Antoni~ Texas. Dr. G. Baxter of Moore Business Forms, studied capsules made by mechanical methods as well as by chemical methods. Mr. Russell G. Arnold of the Bureau of Veteranary Medicine of the Food and Drug Administration draws our attention to the procedures to be used for securing approval of a new animal drug application for the marketing of microencapsulated products. And last but not least, we have a contribution by Mr. G. O. Fanger on "Micro encapsulation a Brief History and Introduction, whose title speaks for itself.

Author : Franklin Lim
Publisher : CRC Press
Page : 169 pages
File Size : 34,93 MB
Release : 2019-06-12
Category : Medical
ISBN : 0429522606

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Published in 1984: For this volume the publishers at CRC Press have chosen to present information on just one important area, namely the biomedical field, where much progress in the application of microencapsulation has been made in recent years.

Author : Willem_M. Kühtreiber
Publisher : Springer Science & Business Media
Page : 457 pages
File Size : 24,86 MB
Release : 2013-12-01
Category : Medical
ISBN : 1461215862

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The concept of using encapsulation for the immunoprotection of transplanted cells was introduced for the first time in the 1960s. "[Microencapsulated cells] might be protected from destruction and from partici pation in immunological processes, while the enclosing membrane would be permeable to small molecules of specific cellular product which could then enter the general extracellular compartment of the recipient. For instance, encapsulated endocrine cells might survive and maintain an effective supply of hormone." (Chang, Ph. D. Thesis, McGill University, 1965; Chang et aI., Can J Physiol PharmacoI44:115-128, 1966). We asked Connaught Laboratories, Ltd., in Toronto to put this concept into practice. In 1980, Lim and Sun from Connaught Laboratories reported on the successful implantation of poly-I-Iysine-alginate encapsu lated rat islets into a foreign host. [Lim and Sun, Science 210:908-909, 1980]. Now many groups around the world are making tremendous progress in the encapsulation of a multitude of cell types. Kiihtreiber, Lanza, and Chick have invited many cell encapsulation groups from around the world to contribute to this book. The result is a very useful reference book in this rapidly growing area. With so many excellent au thors describing in detail the different areas of cell encapsulation, my role here will be to briefly discuss a few points.

Author : Max Donbrow
Publisher : CRC Press
Page : 358 pages
File Size : 25,53 MB
Release : 2020-04-15
Category : Medical
ISBN : 1000087026

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First published in 1992: This book provides a comprehensive look at the design and production of microcapsules, microspheres, and nanoparticles. It discusses the diverse aspects and skills that must be mastered to prepare and test products that will work correctly and be clinically acceptable for human or animal use.

Author : Jose Luis Pedraz
Publisher : Springer Science & Business Media
Page : 167 pages
File Size : 33,51 MB
Release : 2010-12-31
Category : Medical
ISBN : 1441957863

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The advancement of science is ever more contingent upon the interaction of experts vast amount of scientific information being gathered every day that exceeds the ability of any one scientist to acquire. As an illustration of the frantic pace of scientific disc- more acute in the case of scientific fields at the interface of different and seemingly distant areas of study. Amidst these, the field of cell encapsulation brings together an array of diverse disciplines such as molecular biology and biopolymers, gene therapy and inorganic membranes, stem cell biology and physicochemistry, immunology and nanotechnology. Clearly, such range of topics is too broad for any individual scientist the state-of-the-art in the field of cell encapsulation. At the core of this technology, there is an interaction of physicochemical and biological elements forming three distinct layers of complexity. First, the chemistry of the biopolymer dictates the degree of protein adsorption, vascularization, tox- ity and biocompatibility of the microcapsules. Advances in biopolymer science are providing solutions to overcome existing challenges and to improve microcapsules as delivery vehicles. Second, the choice of cells, and more precisely the plethora of in determining the immune response elicited by the host to implanted microcapsules.

Author : Thomas Ming Swi Chang
Publisher : World Scientific
Page : 482 pages
File Size : 40,93 MB
Release : 2007
Category : Medical
ISBN : 9812770372

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50th anniversary of artificial cells -- Basic principles -- Oxygen carriers based on nanobiotechnology -- A nanobiotechnologic therapeutic that transports oxygen and remove oxygen radicals: for stroke, hemorrhagic shock and related conditions -- Nanotechnology-based artificial red blood cells (RBC's) -- Use of enzyme artificial cells for genetic enzyme defects that increase systemic substrates to toxic levels -- Enzyme artificial cells in substrate-dependent tumors and activation of prodrug -- Artificial cells for cell encapsulation -- Artificial cells containing hepatocytes and/or stem cells in regenerative medicine -- Hemoperfusion in poisoning, kidney failure, liver failure, and immunology -- Perspectives on the future of artificial cells as suggested by past research.