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The Science and Applications of Synthetic and Systems Biology

Author : Institute of Medicine
Publisher : National Academies Press
Page : 570 pages
File Size : 12,82 MB
Release : 2011-12-30
Category : Science
ISBN : 0309219396

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Many potential applications of synthetic and systems biology are relevant to the challenges associated with the detection, surveillance, and responses to emerging and re-emerging infectious diseases. On March 14 and 15, 2011, the Institute of Medicine's (IOM's) Forum on Microbial Threats convened a public workshop in Washington, DC, to explore the current state of the science of synthetic biology, including its dependency on systems biology; discussed the different approaches that scientists are taking to engineer, or reengineer, biological systems; and discussed how the tools and approaches of synthetic and systems biology were being applied to mitigate the risks associated with emerging infectious diseases. The Science and Applications of Synthetic and Systems Biology is organized into sections as a topic-by-topic distillation of the presentations and discussions that took place at the workshop. Its purpose is to present information from relevant experience, to delineate a range of pivotal issues and their respective challenges, and to offer differing perspectives on the topic as discussed and described by the workshop participants. This report also includes a collection of individually authored papers and commentary.

Fossil and Recent Biofilms

Author : W.E. Krumbein
Publisher : Springer Science & Business Media
Page : 485 pages
File Size : 32,41 MB
Release : 2013-11-11
Category : Science
ISBN : 9401701938

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MICROBIAL BIOFILMS: PROTECTIVE NICHES IN ANCIENT AND MODERN GEOMICROBIOLOGY J. W. Costerton and Paul Stoodley Center for Biofilm Engineering Montana State University As this book is published based on discussions of a conference that was held in 2001, it may be useful to provide an update on the most recent revelations about biofilms, so that this excellent exposition of the contribution of microbial biofilms to geological processes may be placed in a modem context. The importance of the contribution of microbial biofilms to global processes is only now being appreciated as it is revealed that all terrestrial surfaces are teeming with microbial life in the form of biofilm communities. These communities live on soil particles, in rock fissures, marine and river sediments and at the very extremes of terrestrial habitats from inside Antarctic ice to the walls of deep sea hydrothermal vents. The contribution of these biofilm communities generally went unrecognized because it was the water that was where microbiologists looked for life, not the surfaces, although, evidence of the early association of microbes with surfaces was in fact present in the fossil record (Rasmussen, 2000; Reysenbach, and Cady, 2001). It is also revealing that biofilm formation is found in prokaryotes from the most deeply rooted branches of the phylogenetic tree in both the Archaea and Bacteria kingdoms, the Korarchaeota and Aquificales respectively (Jahnke et al. 2001; Reysenbach et al. 2000).

Biofuels

Author : Avinash Kumar Agarwal
Publisher : Springer
Page : 249 pages
File Size : 13,40 MB
Release : 2017-02-28
Category : Technology & Engineering
ISBN : 9811037914

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This book is intended to serve as a compendium on the state-of-the-art research in the field of biofuels. The book includes chapters on different aspects of biofuels from renowned international experts in the field. The book looks at current research on all aspects of biofuels from raw materials to production techniques. It also includes chapters on analysis of performance of biofuels, particularly biodiesel, in engines. The book incorporates case studies that provide insights into the performance of biofuels in applications such as automotive engines and diesel generators. The contents of the book will be useful to graduate students and researchers working on all aspects of biofuels. The book will also be of use to professionals and policymakers interested in biofuels.

Biofilm Infections

Author : Thomas Bjarnsholt
Publisher : Springer
Page : 0 pages
File Size : 35,70 MB
Release : 2014-10-11
Category : Science
ISBN : 9781489982285

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This book will cover both the evidence for biofilms in many chronic bacterial infections as well as the problems facing these infections such as diagnostics and treatment regimes. A still increasing interest and emphasis on the sessile bacterial lifestyle biofilms has been seen since it was realized that that less than 0.1% of the total microbial biomass lives in the planktonic mode of growth. The term was coined in 1978 by Costerton et al. who defined the term biofilm for the first time.In 1993 the American Society for Microbiology (ASM) recognised that the biofilmmode of growth was relevant to microbiology. Lately many articles have been published on the clinical implications of bacterial biofilms. Both original articles and reviews concerning the biofilm problem are available.

Modern Soil Microbiology, Second Edition

Author : Jan Dirk van Elsas
Publisher : CRC Press
Page : 704 pages
File Size : 18,27 MB
Release : 2006-12-21
Category : Technology & Engineering
ISBN : 9780824727499

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In the ten years since the publication of Modern Soil Microbiology, the study of soil microbiology has significantly changed, both in the understanding of the diversity and function of soil microbial communities and in research methods. Ideal for students in a variety of disciplines, this second edition provides a cutting-edge examination of a fascinating discipline that encompasses ecology, physiology, genetics, molecular biology, and biotechnology, and makes use of biochemical and biophysical approaches. The chapters cover topics ranging from the fundamental to the applied and describe the use of advanced methods that have provided a great thrust to the discipline of soil microbiology. Using the latest molecular analyses, they integrate principles of soil microbiology with novel insights into the physiology of soil microorganisms. The authors discuss the soil and rhizosphere as habitats for microorganisms, then go on to describe the different microbial groups, their adaptive responses, and their respective processes in interactive and functional terms. The book highlights a range of applied aspects of soil microbiology, including the nature of disease-suppressive soils, the use of biological control agents, biopesticides and bioremediation agents, and the need for correct statistics and experimentation in the analyses of the data obtained from soil systems.

Microbial Life on Surface

Author : Ryan D. Lins
Publisher :
Page : 20 pages
File Size : 40,7 MB
Release : 2011
Category : Biofilms
ISBN : 9781618395566

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The Role of Biofilms in the Development and Dissemination of Microbial Resistance within the Food Industry

Author : Efstathios Giaouris
Publisher : MDPI
Page : 100 pages
File Size : 18,31 MB
Release : 2020-12-15
Category : Science
ISBN : 3039435515

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Biofilms are multicellular sessile microbial communities embedded in hydrated extracellular polymeric matrices. Their formation is common in microbial life in most environments, whereas those formed on food-processing surfaces are of considerable interest in the context of food hygiene. Biofilm cells express properties that are distinct from planktonic ones, in particular, due to their notorious resistance to antimicrobial agents. Thus, a special feature of biofilms is that once they have developed, they are hard to eradicate, even when careful sanitization procedures are regularly applied. A large amount of ongoing research has investigated how and why surface-attached microbial communities develop such resistance, and several mechanisms can be acknowledged, such as heterogeneous metabolic activity, cell adaptive responses, diffusion limitations, genetic and functional diversification, and microbial interactions. The articles contained in this Special Issue deal with biofilms of some important food-related bacteria (including common pathogens such as Salmonella enterica, Listeria monocytogenes, and Staphylococcus aureus, as well as spoilage-causing spore-forming bacilli), providing novel insights into their resistance mechanisms and implications, together with novel methods (e.g., use of protective biofilms formed by beneficial bacteria, enzymes) that could be used to overcome resistance and thus improve the safety of our food supply and protect public health.