[PDF] Medical Cannabis And The Effects Of Cannabinoids On Fighting Cancer Multiple Sclerosis Epilepsy Parkinsons And Other Neurodegenerative Diseases eBook

Author : Zeine, Rana R.
Publisher : IGI Global
Page : 427 pages
File Size : 44,7 MB
Release : 2023-03-07
Category : Medical
ISBN : 1668456532

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Research on the therapeutic efficacy of cannabinoids has demonstrated that cannabidiol (CBD), either alone or in 1:1 mixtures with delta-9-tetrahydrocannabinol (THC), can effectively treat animals in experimental models of neuroinflammatory, demyelinative, neurodegenerative, neuropsychiatric, and neoplastic diseases. Short-term, small-scale, human cohorts, observational studies, randomized, non-randomized, placebo-controlled, and uncontrolled clinical trials have provided low-certainty and moderate-certainty evidence that medical marijuana can reduce spasticity, neuropathic pain, neuroinflammation, anxiety, sleep disturbance, urinary bladder dysfunction, frequency and duration of seizure, tumor size, and metastasis as well as promote overall cancer survival. Medical Cannabis and the Effects of Cannabinoids on Fighting Cancer, Multiple Sclerosis, Epilepsy, Parkinson's, and Other Neurodegenerative Diseases presents the findings from clinical and basic medical scientists who are investigating the cellular and molecular mechanisms of cannabinoid-mediated inhibition of innate and adaptive immune responses, mobilization of myeloid-derived immunosuppressive cells, enhancement of neuroprotection, facilitation of oligodendrocyte survival, promotion of CNS progenitor cell differentiation to support regeneration and remyelination, arrest of tumor cell proliferation, decrease in tumor cell adhesion, disruption of tumor angiogenesis, inhibition of endothelial cells, and prevention of cancer metastasis by inhibition of cell migration. The chapters further discuss pharmacologic challenges and precisely how the delicate balance between the opposing effects of various types of cannabinoid receptors can be controlled by manipulating specific membrane channels and signaling pathways to achieve favorable long-term clinicopathologic outcomes in oncology and neurology. Covering topics such as neurodegenerative diseases, spectroscopic applications, and ethical issues, this premier reference source is an essential resource for medical professionals, pharmacists, hospital administrators, government officials, students and faculty of higher education, librarians, researchers, and academicians.

Author : Joseph Rosado
Publisher :
Page : 214 pages
File Size : 35,26 MB
Release : 2019-08-20
Category :
ISBN : 9781687506528

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"Insightful and thought-provoking."--DIANE D. RODRIGUEZ"I've researched and written about this topic several times before and never have I seen this explained so well!"--CHRISTINA DEBUSKIn Hope & Healing, Dr. Joseph Rosado lays out the plant's surprising history and controversy, the challenges physicians face when recommending it, and the benefits his thousands of patients have enjoyed from its proper use. With case studies and personal experiences, Hope & Healing has as much science as personal charm. If you've wondered if cannabis might offer hope for you or a loved one this book is for you. In it you'll discover:* The original source of attacks on cannabis,* What is cannabis?* Why it works so well with the human body,* What discoveries are being made today? * How to safely use cannabis,* What is the probable future of cannabis both for medicine and recreation?With a foreword by legendary Professor Lumír Ondřej Hanus and quotes by a surprising array of leaders who support its use, Hope & Healing is the book that could change your path to health and happiness, especially if you've ever wondered if there was a better approach than surgery or powerful and expensive prescription drugs laden with side effects.Read the book that is changing minds in surprising places. Buy, read, and share Hope & Healing today!

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
Page : 487 pages
File Size : 17,9 MB
Release : 2017-03-31
Category : Science
ISBN : 0309453070

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Significant changes have taken place in the policy landscape surrounding cannabis legalization, production, and use. During the past 20 years, 25 states and the District of Columbia have legalized cannabis and/or cannabidiol (a component of cannabis) for medical conditions or retail sales at the state level and 4 states have legalized both the medical and recreational use of cannabis. These landmark changes in policy have impacted cannabis use patterns and perceived levels of risk. However, despite this changing landscape, evidence regarding the short- and long-term health effects of cannabis use remains elusive. While a myriad of studies have examined cannabis use in all its various forms, often these research conclusions are not appropriately synthesized, translated for, or communicated to policy makers, health care providers, state health officials, or other stakeholders who have been charged with influencing and enacting policies, procedures, and laws related to cannabis use. Unlike other controlled substances such as alcohol or tobacco, no accepted standards for safe use or appropriate dose are available to help guide individuals as they make choices regarding the issues of if, when, where, and how to use cannabis safely and, in regard to therapeutic uses, effectively. Shifting public sentiment, conflicting and impeded scientific research, and legislative battles have fueled the debate about what, if any, harms or benefits can be attributed to the use of cannabis or its derivatives, and this lack of aggregated knowledge has broad public health implications. The Health Effects of Cannabis and Cannabinoids provides a comprehensive review of scientific evidence related to the health effects and potential therapeutic benefits of cannabis. This report provides a research agendaâ€"outlining gaps in current knowledge and opportunities for providing additional insight into these issuesâ€"that summarizes and prioritizes pressing research needs.

Author : British Medical Association
Publisher : CRC Press
Page : 164 pages
File Size : 28,89 MB
Release : 1997-11-18
Category : Medical
ISBN : 9789057023187

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At the last Annual Representative Meeting of the British Medical Association a motion was passed that `certain additional cannabinoids should be legalized for wider medicinal use.'' This report supports this landmark statement by reviewing the scientific evidence for the therapeutic use of cannabinoids and sets the agenda for change. It will be welcomed by those who believe that cannabinoids can be used in medical treatment. The report discusses in a clear and readable form the use and adverse effects of the drug for nausea, multiple sclerosis, pain, epilepsy, glaucoma, and asthma.

Author : Eric Murillo-Rodriguez
Publisher : Springer Nature
Page : 163 pages
File Size : 45,80 MB
Release : 2020-12-17
Category : Science
ISBN : 3030573699

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This volume highlights the recent advances in the understanding of the endocannabinoid system and the likely benefit from the therapeutic effects of cannabinoid treatment in a variety of health issues. Archeological evidence has shown that Cannabis has a long history of use for multiple purposes, including the treatment of medical conditions. The primary active constituent of the hemp plant Cannabis sativa, delta 9-tetrahydrocannabinol (Δ9-THC), causes euphoria, enhancement of sensory perception, tachycardia, antinociception, difficulties in concentration and impairment of memory, among other effects. Despite these undesirable effects, signaling is mostly inhibitory and suggests a putative role for cannabinoids as therapeutic agents by managing several diseases where inhibition of neurotransmitter release would be beneficial. The themes of this book have been edited and written by world-leaders in the field, The contents of the volume aims at readers from a range of academic and professional disciplines, such as biomedicine, several areas of biology, neurology, clinical medicine and pharmacy.

Author : Joseph Rosado
Publisher : Coastal Press
Page : 212 pages
File Size : 39,71 MB
Release : 2019-04-20
Category :
ISBN : 9781946875341

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Medical cannabis pioneer Dr. Joseph Rosado lays out the surprising history of the plant, the reasons for the controversy that surrounds it to this day, the challenges physicians still face when recommending all-natural solutions in the face of Big Medicine, and the benefits he and his thousands of patients have enjoyed from its proper use.

Author : Institute of Medicine
Publisher : National Academies Press
Page : 216 pages
File Size : 25,39 MB
Release : 2000-12-30
Category : Medical
ISBN : 0309065313

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Some people suffer from chronic, debilitating disorders for which no conventional treatment brings relief. Can marijuana ease their symptoms? Would it be breaking the law to turn to marijuana as a medication? There are few sources of objective, scientifically sound advice for people in this situation. Most books about marijuana and medicine attempt to promote the views of advocates or opponents. To fill the gap between these extremes, authors Alison Mack and Janet Joy have extracted critical findings from a recent Institute of Medicine study on this important issue, interpreting them for a general audience. Marijuana As Medicine? provides patientsâ€"as well as the people who care for themâ€"with a foundation for making decisions about their own health care. This empowering volume examines several key points, including: Whether marijuana can relieve a variety of symptoms, including pain, muscle spasticity, nausea, and appetite loss. The dangers of smoking marijuana, as well as the effects of its active chemical components on the immune system and on psychological health. The potential use of marijuana-based medications on symptoms of AIDS, cancer, multiple sclerosis, and several other specific disorders, in comparison with existing treatments. Marijuana As Medicine? introduces readers to the active compounds in marijuana. These include the principal ingredient in Marinol, a legal medication. The authors also discuss the prospects for developing other drugs derived from marijuana's active ingredients. In addition to providing an up-to-date review of the science behind the medical marijuana debate, Mack and Joy also answer common questions about the legal status of marijuana, explaining the conflict between state and federal law regarding its medical use. Intended primarily as an aid to patients and caregivers, this book objectively presents critical information so that it can be used to make responsible health care decisions. Marijuana As Medicine? will also be a valuable resource for policymakers, health care providers, patient counselors, medical faculty and studentsâ€"in short, anyone who wants to learn more about this important issue.

Author : Linda A. Parker
Publisher : MIT Press
Page : 249 pages
File Size : 40,45 MB
Release : 2018-09-25
Category : Science
ISBN : 0262536609

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A review of the scientific evidence on the effects of cannabinoids on brain and behavioral functioning, with an emphasis on potential therapeutic use. The cannabis plant has been used for recreational and medicinal purposes for more than 4,000 years, but the scientific investigation into its effects has only recently yielded useful results. In this book, Linda Parker offers a review of the scientific evidence on the effects of cannabinoids on brain and behavioral functioning, with an emphasis on potential therapeutic uses. Parker describes the discovery of tetrahydocannbinol (THC), the main psychoactive component of cannabis, and the further discovery of cannabinoid receptors in the brain. She explains that the brain produces chemicals similar to THC, which act on the same receptors as THC, and shows that the endocannabinoid system is involved in all aspects of brain functioning. Parker reports that cannabis contains not only the psychoactive compound THC, but also other compounds of potential therapeutic benefit, and that one of them, cannabidiol (CBD), shows promise for the treatment of pain, anxiety, and epilepsy. Parker reviews the evidence on cannabinoids and anxiety, depression, mood, sleep, schizophrenia, learning and memory, addiction, sex, appetite and obesity, chemotherapy-induced nausea, epilepsy, and such neurodegenerative disorders as multiple sclerosis and Alzheimer's Disease. Each chapter also links the scientific evidence to historical and anecdotal reports of the medicinal use of cannabis. As debate about the medical use of marijuana continues, Parker's balanced and objective review of the fundamental science and potential therapeutic effects of cannabis is especially timely.

Author : Institute of Medicine
Publisher : National Academies Press
Page : 288 pages
File Size : 12,33 MB
Release : 1999-06-10
Category : Medical
ISBN : 0309132908

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The medical use of marijuana is surrounded by a cloud of social, political, and religious controversy, which obscures the facts that should be considered in the debate. This book summarizes what we know about marijuana from evidence-based medicineâ€"the harm it may do and the relief it may bring to patients. The book helps the reader understand not only what science has to say about medical marijuana but also the logic behind the scientific conclusions. Marijuana and Medicine addresses the science base and the therapeutic effects of marijuana use for medical conditions such as glaucoma and multiple sclerosis. It covers marijuana's mechanism of action, acute and chronic effects on health and behavior, potential adverse effects, efficacy of different delivery systems, analysis of the data about marijuana as a gateway drug, and the prospects for developing cannabinoid drugs. The book evaluates how well marijuana meets accepted standards for medicine and considers the conclusions of other blue-ribbon panels. Full of useful facts, this volume will be important to anyone interested in informed debate about the medical use of marijuana: advocates and opponents as well as policymakers, regulators, and health care providers.

Author : Victor R Preedy
Publisher : Elsevier
Page : 602 pages
File Size : 18,44 MB
Release : 2023-06-02
Category : Medical
ISBN : 0323915787

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Medicinal Usage of Cannabis and Cannabinoids offers readers a comprehensive reference on the medical usage and symptom relief provided by these compounds in a variety of disorders. With coverage of neurological diseases like Alzheimer’s and Parkinson’s, and a wide range of other afflictions including depression, anxiety, nausea and cancer, this broad coverage allows readers to learn about symptom control, along with the physiological, psychological and pharmacological effects of these compounds. Unique case reports are provided as well. This volume provides a platform for research on the use of these compounds in improving patient care, brain function and neurological dysfunction. Summarizes the medicinal usage of cannabis and cannabinoids in a variety of conditions Contains chapter abstracts, key facts, a dictionary and a summary Examines symptom control of conditions such as depression, anxiety and sleep Discusses cannabis usage in Alzheimer’s, Parkinson’s, Multiple Sclerosis and cancer Features case reports and chapters on the physiological, psychological and pharmacological effects