[PDF] Mammalian Models For Biomedical Research eBook

Author :
Publisher :
Page : 82 pages
File Size : 34,93 MB
Release : 2000-01-01
Category :
ISBN : 9780788185144

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The Comparative Medicine Program (CMP) of the NIH Nat. Center for Resources helps meet the needs of biomedical researchers for high quality, disease-free animals and specialized animal research facilities. The purpose of this directory is to inform researchers of the resources provided for comparative biomedical research by the CMP and how to access them. Examples include facilities for the full spectrum of biomedical research using the common species of laboratory primates; resources for the diagnosis and investigation of diseases of lab animals; sources of lab animals, including specific genetic types; and specific animal models.

Author : P. Michael Conn
Publisher : Springer Science & Business Media
Page : 756 pages
File Size : 12,36 MB
Release : 2008
Category : Medical
ISBN : 1588299333

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The collection of systems represented in Sourcebook of genomic programs, although this work is certainly well Models for Biomedical Research is an effort to re?ect the represented and indexed. diversity and utility of models that are used in biomedicine. Some models have been omitted due to page limitations That utility is based on the consideration that observations and we have encouraged the authors to use tables and made in particular organisms will provide insight into the ? gures to make comparisons of models so that observations workings of other, more complex, systems. Even the cell not available in primary publications can become useful to cycle in the simple yeast cell has similarities to that in the reader. humans and regulation with similar proteins occurs. We thank Richard Lansing and the staff at Humana for Some models have the advantage that the reproductive, guidance through the publication process. mitotic, development or aging cycles are rapid compared As this book was entering production, we learned of the with those in humans; others are utilized because individual loss of Tom Lanigan, Sr. Tom was a leader and innovator proteins may be studied in an advantageous way and that in scienti?c publishing and a good friend and colleague to have human homologs. Other organisms are facile to grow all in the exploratory enterprise. We dedicate this book to in laboratory settings or lend themselves to convenient analy- his memory. We will miss him greatly.

Author : Avril D. Woodhead
Publisher : CRC Press
Page : 408 pages
File Size : 32,90 MB
Release : 1989-11-30
Category : Medical
ISBN : 9780849347634

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This book provides essential knowledge and informa-tion required to adequately assess useful alternatives from among the lower vertebrates and the invertebrates. This volume highlights unfamiliar and underde-veloped organisms that have the potential to become very satisfactory surrogates for biomedical research. A practical guide aimed at disseminating information to researchers about new models, this work provides compara-tive biomedical studies at many levels of the phyloge-netic ladder.

Author : National Research Council
Publisher : National Academies Press
Page : 85 pages
File Size : 37,66 MB
Release : 1998-02-16
Category : Science
ISBN : 0309060354

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Printbegrænsninger: Der kan printes 10 sider ad gangen og max. 40 sider pr. session.

Author : National Research Council
Publisher : National Academies Press
Page : 113 pages
File Size : 50,87 MB
Release : 1988-02-01
Category : Science
ISBN : 0309038391

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Scientific experiments using animals have contributed significantly to the improvement of human health. Animal experiments were crucial to the conquest of polio, for example, and they will undoubtedly be one of the keystones in AIDS research. However, some persons believe that the cost to the animals is often high. Authored by a committee of experts from various fields, this book discusses the benefits that have resulted from animal research, the scope of animal research today, the concerns of advocates of animal welfare, and the prospects for finding alternatives to animal use. The authors conclude with specific recommendations for more consistent government action.

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
Page : 123 pages
File Size : 13,15 MB
Release : 2019-08-26
Category : Science
ISBN : 0309488516

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The marmoset, a type of small monkey native to South America, is a research model of increasing importance for biomedical research in the United States and globally. Marmosets offer a range of advantages as animal models in neuroscience, aging, infectious diseases, and other fields of study. They may be particularly useful for the development of new disease models using genetic engineering and assisted reproductive technologies. However, concerns have been voiced with respect to the development of new marmoset-based models of disease, ethical considerations for their use, the supply of marmosets available for research, and gaps in guidance for their care and management. To explore and address these concerns, the Roundtable on Science and Welfare in Laboratory Animal Use hosted a public workshop on October 22-23, 2018, in Washington, DC. The workshop focused on the availability of marmosets in the United States and abroad; animal welfare and ethical considerations stemming from the use of wildtype and genetically modified marmosets; and standards of housing and care, dietary needs, and feeding requirements for marmosets in captivity. This publication summarizes the presentations and discussions from the workshop.

Author : National Research Council
Publisher : National Academies Press
Page : 348 pages
File Size : 23,62 MB
Release : 2000-12-21
Category : Nature
ISBN : 0309070864

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Scientific Frontiers in Developmental Toxicology and Risk Assessment reviews advances made during the last 10-15 years in fields such as developmental biology, molecular biology, and genetics. It describes a novel approach for how these advances might be used in combination with existing methodologies to further the understanding of mechanisms of developmental toxicity, to improve the assessment of chemicals for their ability to cause developmental toxicity, and to improve risk assessment for developmental defects. For example, based on the recent advances, even the smallest, simplest laboratory animals such as the fruit fly, roundworm, and zebrafish might be able to serve as developmental toxicological models for human biological systems. Use of such organisms might allow for rapid and inexpensive testing of large numbers of chemicals for their potential to cause developmental toxicity; presently, there are little or no developmental toxicity data available for the majority of natural and manufactured chemicals in use. This new approach to developmental toxicology and risk assessment will require simultaneous research on several fronts by experts from multiple scientific disciplines, including developmental toxicologists, developmental biologists, geneticists, epidemiologists, and biostatisticians.