[PDF] Lipotropin And Related Peptides eBook

Author : Choh Hao Li
Publisher : Elsevier
Page : 219 pages
File Size : 27,46 MB
Release : 2012-12-02
Category : Nature
ISBN : 0323159907

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Hormonal Proteins and Peptides, Volume V: Lipotropin and Related Peptides deals with peptides that have neurobiological properties. This book consists of five chapters. Chapter 1 reviews the chemistry of melanotropins, while Chapter 2 describes the most potent morphinelike peptide, ?-endorphin. The third chapter summarizes the chemistry and biology of lipotropins that were discovered and characterized from 1964 to 1965. Chapter 4 examines the properties and physiological role of neurophysins. A historical perspective of the achievements of the Uppsala School regarding the separation methods and biographical sketch of Arne Tiselius are presented at the last chapter. This book is recommended for endocirnologists, clinicians, and students researching on lipotropins.

Author : Jens F. Rehfeld
Publisher : Springer Science & Business Media
Page : 245 pages
File Size : 12,75 MB
Release : 2010-03-10
Category : Science
ISBN : 3642118364

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The concept of hormonal regulation using intercellular peptide messengers dates back to the discovery of secretin in 1902. The concept was simple: A peptide is released from specific hormone producing cells, endocrine cells, into circulation upon stimulation of the cells. The peptide hormone travels via blood to its target, the cells of which are equipped with specific receptors for high-affinity binding of the particular peptide hormone. Receptor binding subsequently elicits action of the target cells. This concept has been seriously challenged by modern biochemistry and cell biology. Thus, it is now well established that the gene of a specific peptide hormone may be expressed in different types of endocrine cells, in neurons, and in some instances also in adipocytes, myocytes, osteoblasts, and immune cells. Today, only a few hormones – including the old master hormone insulin – represent the original endocrine paradigm. Instead, the widespread cellular synthesis now raises the qu- tion of how the body maintains the regulation of its functions by peptide hormones when a hormone may originate from a variety of cells.

Author : Anthony W. Norman
Publisher : Academic Press
Page : 823 pages
File Size : 37,35 MB
Release : 2014-06-28
Category : Science
ISBN : 1483258106

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Hormones provides a comprehensive treatment of human hormones viewed in the light of modern theories of hormone action and in the context of current understanding of subcellular and cellular architecture and classical organ physiology. The book begins with discussions of the first principles of hormone action and the seven classes of steroid hormones and their chemistry, biosynthesis, and metabolism. These are followed by separate chapters that address either a classical endocrine system, e.g., hypothalamic hormones, posterior pituitary hormones, anterior pituitary hormones, ,thyroid hormones, pancreatic hormones, gastrointestinal hormones, calcium regulating hormones, adrenal corticoids, hormones of the adrenal medulla, androgens, estrogens and progestins, and pregnancy and lactation hormones; or newer domains of hormone action which are essential to a comprehensive understanding of hormone action, including prostaglandins, thymus hormones, and pineal hormones. The book concludes with a presentation of hormones of the future, i.e., cell growth factors. This book is intended for use by first-year medical students, graduate students, and advanced undergraduates in the biological sciences. It is also hoped that this book will fill the void that exists for resource materials for teaching cellular and molecular endocrinology and that it will be employed as an equal partner with most standard biochemistry textbooks to provide a comprehensive and balanced coverage of this realm of biology.

Author : Fidel Toldra
Publisher : Academic Press
Page : 819 pages
File Size : 44,93 MB
Release : 2021-06-17
Category : Science
ISBN : 0128214384

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Biologically Active Peptides: From Basic Science to Applications for Human Health stands as a comprehensive resource on bioactive peptide science and applications. With contributions from more than thirty global experts, topics discussed include bioactive peptide science, structure-activity relationships, best practices for their study and production, and their applications. In the interdisciplinary field of bioactive peptides, this book bridges the gap between basic peptide chemistry and human physiology, while reviewing recent advances in peptide analysis and characterization. Methods and technology-driven chapters offer step-by-step guidance in peptide preparation from different source materials, bioactivity assays, analysis and identification of bioactive peptides, encoding bioactive peptides. Later, applications across disease areas and medical specialties are examined in-depth, including the use of bioactive peptides in treating obesity, diabetes, osteoporosis, mental health disorders, food allergies, and joint health, among other disorders, as well as bioactive peptides for sensory enhancement, sports and clinical nutrition, lowering cholesterol, improving cardiovascular health, and driving advances in biotechnology. Discusses the latest advances in bioactive peptide chemistry, functionality and analysis Offers step-by-step instruction in applying new technologies for peptide extraction, protection, production and encoding, as well as employing bioactive peptide sequencing and bioactivity assays in new research Effectively links basic peptide chemistry, human biology and disease Features chapter contributions from international experts across disciplines and applications

Author : Kamyar M. Hedayat
Publisher : Academic Press
Page : 306 pages
File Size : 46,81 MB
Release : 2019-06-18
Category : Science
ISBN : 0128173262

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The Theory of Endobiogeny Volume 1: Global Systems Thinking and Biological Modeling for Clinical Medicine offers researchers and clinicians a detailed introduction to the theory of Endobiogeny. The book presents a new approach to medicine that is at once scientific and humanistic, quantitative, and qualitative. The philosophical and experimental basis of a global complex systems approach to physiology is presented along with a mathematical approach to modeling the dynamism of the terrain. The importance of the history and physical examination are renewed as a source of “big data readily available to clinicians for greater insight into the patient’s state. Expansion of the therapeutic compendium is proposed based on a rational, clinical approach correlated to mathematical indicators of the physiologic state. What is proposed in this work is a fundamental shift in scientific thinking with a resulting expansion of the boundaries of clinical medicine for the 21st century and beyond. Extends systems biology from the cellular to the integrative physiologic level Moves the functional medicine approach to a higher level of integration and true global systems thinking Presents mathematical tools and proofs of formulas related to the biology of functions: a biological modeling system based on the theory of endobiogeny. The biology of functions has assisted clinicians in conceptualizing, treating, and objectively monitoring the longitudinal effects of treatment through the evolution of the patient’s unique phenotypic expression of terrain