[PDF] Landmark Experiments In Molecular Biology eBook

Author : Michael Fry
Publisher : Academic Press
Page : 572 pages
File Size : 32,15 MB
Release : 2016-06-10
Category : Science
ISBN : 012802108X

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Landmark Experiments in Molecular Biology critically considers breakthrough experiments that have constituted major turning points in the birth and evolution of molecular biology. These experiments laid the foundations to molecular biology by uncovering the major players in the machinery of inheritance and biological information handling such as DNA, RNA, ribosomes, and proteins. Landmark Experiments in Molecular Biology combines an historical survey of the development of ideas, theories, and profiles of leading scientists with detailed scientific and technical analysis. Includes detailed analysis of classically designed and executed experiments Incorporates technical and scientific analysis along with historical background for a robust understanding of molecular biology discoveries Provides critical analysis of the history of molecular biology to inform the future of scientific discovery Examines the machinery of inheritance and biological information handling

Author : Pascal Leclair
Publisher : CRC Press
Page : 253 pages
File Size : 31,50 MB
Release : 2023-07-31
Category : Science
ISBN : 1000897575

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Proteins are the workhorses of cells, performing most of the important functions which allow cells to use nutrients and grow, communicate among each other, and importantly, die if aberrant behavior is detected. How were proteins discovered? What is their role in cells? How do dysfunctional proteins give rise to cancers? Landmark Experiments in Protein Science explores the manner in which the inner workings of cells were elucidated, with a special emphasis on the role of proteins. Experiments are discussed in a manner as to understand what questions were being asked that prompted the experiments and what technical challenges were faced in the process; and results are presented and discussed using primary data and graphs. Key Features Describes landmark experiments in cell biology and biochemistry. Discusses the "How" and "Why" of historically important experiments. Includes primary, original data and graphs. Emphasizes biological techniques, that help understand how many of the experiments performed were possible. Documents, chronologically, how each result fed into the next experiments.

Author : Patrick Linder
Publisher : CSHL Press
Page : 311 pages
File Size : 46,84 MB
Release : 2006
Category : Science
ISBN : 0879696435

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The yeasts have been important experimental organisms for more than 50 years. This volume contains over 100 selected papers, in sections with introductions that describe the process of discovery and the context and significance of the research. The selections include early classics as well as recent advances in areas such as signal transduction, membrane trafficking, protein turnover, and genomics. This book is designed as a guide for a literature-based course.

Author : Joseph G. Gall
Publisher : CSHL Press
Page : 776 pages
File Size : 25,83 MB
Release : 2001
Category : Cells
ISBN : 9780879696023

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Annotation Contains 42 seminal papers illustrating advances in cell biology, along with brief commentaries that place the papers in historical and intellectual context. All papers are studies of eukaryotes, and are grouped according to themes of genome organization and replication, transcription, nuclear envelope and nuclear import, mitosis and cell cycle control, cell membrane and extracellular matrix, protein synthesis and membrane traffic, and cytoskeleton. Lacks a subject index. Gall teaches embryology at the Carnegie Institution. McIntosh teaches cell biology at the University of Colorado. Annotation c. Book News, Inc., Portland, OR (booknews.com).

Author : Harvey Lodish
Publisher : W.H. Freeman
Page : 1344 pages
File Size : 49,79 MB
Release : 2000
Category :
ISBN : 9780716730538

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With its acclaimed author team, cutting-edge content, emphasis on medical relevance, and coverage based on landmark experiments, "Molecular Cell Biology" has justly earned an impeccable reputation as an authoritative and exciting text. The new Sixth Edition features two new coauthors, expanded coverage of immunology and development, and new media tools for students and instructors.

Author : Frederic Lawrence Holmes
Publisher : Yale University Press
Page : 516 pages
File Size : 32,90 MB
Release : 2008-10-01
Category : Science
ISBN : 0300129661

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In 1957 two young scientists, Matthew Meselson and Frank Stahl, produced a landmark experiment confirming that DNA replicates as predicted by the double helix structure Watson and Crick had recently proposed. It also gained immediate renown as a “most beautiful” experiment whose beauty was tied to its simplicity. Yet the investigative path that led to the experiment was anything but simple, Frederic L. Holmes shows in this masterful account of Meselson and Stahl’s quest. This book vividly reconstructs the complex route that led to the Meselson-Stahl experiment and provides an inside view of day-to-day scientific research--its unpredictability, excitement, intellectual challenge, and serendipitous windfalls, as well as its frustrations, unexpected diversions away from original plans, and chronic uncertainty. Holmes uses research logs, experimental films, correspondence, and interviews with the participants to record the history of Meselson and Stahl’s research, from their first thinking about the problem through the publication of their dramatic results. Holmes also reviews the scientific community’s reception of the experiment, the experiment’s influence on later investigations, and the reasons for its reputation as an exceptionally beautiful experiment.

Author : Harvey F. Lodish
Publisher : W.H. Freeman
Page : 973 pages
File Size : 30,51 MB
Release : 2012
Category : Biología molecular
ISBN : 9781464109812

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With its acclaimed authors, cutting-edge content, emphasis on medical relevance and landmark experiments, Molecular Cell Biology is an impeccable textbook. Updated throughout, the seventh edition features new co-author Angelika Amon, a completely rewritten chapter on the Cell Cycle and significant updates to experimental techniques.