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A Rip in Heaven

Author : Jeanine Cummins
Publisher : Penguin
Page : 320 pages
File Size : 15,48 MB
Release : 2004-06-01
Category : True Crime
ISBN : 1440627916

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The acclaimed author of American Dirt reveals the devastating effects of a shocking tragedy in this landmark true crime book—the first ever to look intimately at the experiences of both the victims and their families. A Rip in Heaven is Jeanine Cummins’ story of a night in April, 1991, when her two cousins Julie and Robin Kerry, and her brother, Tom, were assaulted on the Old Chain of Rocks Bridge, which spans the Mississippi River just outside of St. Louis. When, after a harrowing ordeal, Tom managed to escape the attackers and flag down help, he thought the nightmare would soon be over. He couldn’t have been more wrong. Tom, his sister Jeanine, and their entire family were just at the beginning of a horrific odyssey through the aftermath of a violent crime, a world of shocking betrayal, endless heartbreak, and utter disillusionment. It was a trial by fire from which no family member would emerge unscathed.

Frida

Author : Hayden Herrera
Publisher : Bloomsbury Paperbacks
Page : 528 pages
File Size : 29,5 MB
Release : 2018-06-28
Category :
ISBN : 9781526605313

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The beautifully illustrated and utterly absorbing biography of one of the twentieth century's most transfixing artists Frida is the story of one of the twentieth century 's most extraordinary women, the painter Frida Kahlo. Born near Mexico City, she grew up during the turbulent days of the Mexican Revolution and, at eighteen, was the victim of an accident that left her crippled and unable to bear children. To salvage what she could from her unhappy situation, Kahlo had to learn to keep still so she began to paint. Kahlo 's unique talent was to make her one of the century 's most enduring artists. But her remarkable paintings were only one element of a rich and dramatic life. Frida is also the story of her tempestuous marriage to the muralist Diego Rivera, her love affairs with numerous, diverse men such as Isamu Noguchi and Leon Trotsky, her involvement with the Communist Party, her absorption in Mexican folklore and culture, and of the inspiration behind her unforgettable art.

Last Kiss

Author : Luanne Rice
Publisher : Bantam
Page : 354 pages
File Size : 15,7 MB
Release : 2008-07-15
Category : Fiction
ISBN : 0553905392

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New York Times bestselling author Luanne Rice returns to Hubbard’s Point, Connecticut, and to characters from her beloved Beach Girls, to tell the haunting story of a close-knit community grappling with a heartbreaking mystery, and of a woman rebuilding her world and reclaiming a love she believed lost a lifetime ago. A face on a poster, a name in the news, an inexplicable tragedy. A promising young man goes out one warm summer evening and is found dead—murdered—less than twenty-four hours later. No motive. No clues. No answers. Most people reflect briefly on the disturbing headlines, perhaps say a silent prayer of safely removed sympathy, and go on with their lives. But what if the young man was your son? Or your true love? Nearly a year after the death of eighteen-year-old Charlie, singer-songwriter Sheridan Rosslare still hasn’t played a note of the music that was once her life’s passion. Tucked away in the beach house where she raised her only child, she lives with her memories of him and a grief too big to share even with her beloved sisters or her dear friend Stevie Moore. Nor can Stevie comfort Charlie’s heartbroken girlfriend, Nell Kilvert, whom she regards as a daughter. Nell won’t rest until she finds out what really happened to the boy she loved. Out of the past she summons a man she believes cares enough, and is tough enough, to uncover the truth—Sheridan’s long-ago soul mate, Gavin Dawson. Now Gavin’s boat, the Squire Toby, sits anchored in the harbor within sight of the window of the woman he once loved, still loves, and will always love. Sheridan, too, had once fervently believed in the miraculous power of love and healing, forgiveness, connection, and reconnection. But that faith died along with her son…. Unfolding among the Hubbard’s Point people and places that fans have come to treasure, and replete with feeling and mystery, Last Kiss weighs the power of the past to heal as well as wound, in a captivating tale of love, loss, and redemption that no reader will ever forget.

Principles for Building Resilience

Author : Reinette Biggs
Publisher : Cambridge University Press
Page : 317 pages
File Size : 20,66 MB
Release : 2015-04-02
Category : Business & Economics
ISBN : 110708265X

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Reflecting the very latest research, this book provides an in-depth review of the role of resilience in the management of social-ecological systems and the ecosystem services they provide. Leaders in the field outline seven principles for building resilience in social-ecological systems, examining how these can be applied to advance sustainability.

Translational Medicine

Author : Joy A. Cavagnaro
Publisher : CRC Press
Page : 952 pages
File Size : 35,69 MB
Release : 2021-11-26
Category : Medical
ISBN : 1000471853

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Translational Medicine: Optimizing Preclinical Safety Evaluation of Biopharmaceuticals provides scientists responsible for the translation of novel biopharmaceuticals into clinical trials with a better understanding of how to navigate the obstacles that keep innovative medical research discoveries from becoming new therapies or even making it to clinical trials. The book includes sections on protein-based therapeutics, modified proteins, oligonucleotide-based therapies, monoclonal antibodies, antibody–drug conjugates, gene and cell-based therapies, gene-modified cell-based therapies, combination products, and therapeutic vaccines. Best practices are defined for efficient discovery research to facilitate a science-based, efficient, and predictive preclinical development program to ensure clinical efficacy and safety. Key Features: Defines best practices for leveraging of discovery research to facilitate a development program Includes general principles, animal models, biomarkers, preclinical toxicology testing paradigms, and practical applications Discusses rare diseases Discusses "What-Why-When-How" highlighting different considerations based upon product attributes. Includes special considerations for rare diseases About the Editors Joy A. Cavagnaro is an internationally recognized expert in preclinical development and regulatory strategy with an emphasis on genetic medicines.. Her 40-year career spans academia, government (FDA), and the CRO and biotech industries. She was awarded the 2019 Arnold J Lehman Award from the Society of Toxicology for introducing the concept of science-based, case-by-case approach to preclinical safety evaluation, which became the foundation of ICH S6. She currently serves on scientific advisory boards for advocacy groups and companies and consults and lectures in the area of preclinical development of novel therapies. Mary Ellen Cosenza is a regulatory toxicology consultant with over 30 years of senior leadership experience in the biopharmaceutical industry in the U.S., Europe, and emerging markets. She has held leadership position in both the American College of Toxicology (ACT) and the International Union of Toxicology (IUTOX) and is also an adjunct assistant professor at the University of Southern California where she teaches graduate-level courses in toxicology and regulation of biologics.

Between the Sheets

Author : Molly O'Keefe
Publisher : Bantam
Page : 370 pages
File Size : 28,69 MB
Release : 2014-07-29
Category : Fiction
ISBN : 0345549031

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NAMED ONE OF THE BEST BOOKS OF THE YEAR BY RT BOOK REVIEWS Sure to thrill readers of Susan Mallery and Rachel Gibson, Molly O’Keefe’s sizzling series cranks up the tension as a bad boy rides into town on his motorcycle—and teaches the girl next door to lose control when it comes to desire. After years of running, Wyatt Svenson has now parked himself in Bishop, Arkansas, trying to do the right thing and parent a son he didn’t even know he had until recently. Over six feet tall and packed with muscles and power, Ty likes to get his hands dirty, fixing his motorcycle at night and keeping his mind away from the mistakes he’s made. Then his pretty neighbor shows up on his driveway, doesn’t bother to introduce herself, and complains about the noise. First impression? She should loosen up. Funny that she turns out to be his son’s elementary school art teacher—and the only one willing to help his troubled boy. Ty needs her. In more ways than one. Though Shelby Monroe is safe in her structured life, she is drawn to Ty’s bad-boy edge and rugged sexuality. What if she just lets it all go: her worries about her mother, her fear of heartbreak, and her tight self control? What if she grabs Ty and takes a ride on the wild side? “What if” becomes reality—intense, exhilarating . . . and addictive. But Ty wants more than a secret affair. He wants it all with Shelby. But will she take a chance and open her heart? Ty is determined to convince Shelby to take the biggest risk of her life: on him. Praise for Between the Sheets “Phenomenal . . . The story is deep, complex, and rich, with emotional tones of hope, loss, regret, pain, and so many flavors of love.”—Publishers Weekly (starred review) “The characters are genuine, their stories are authentic and there is a rawness of emotion that is completely unexpected. The chemistry Ty and Shelby share is electric and their sex scenes are sizzling on a whole new level. This is a fantastic read that surprises and thoroughly delights.”—RT Book Reviews (4-1/2 stars, Top Pick) “Dark, edgy, and emotionally turbulent, Between the Sheets is a . . . modern-day romance that speaks of second chances, love, heartbreak, redemption, and hope.”—Smexy Books “Once again, Molly O’Keefe explodes the traditional trope and creates characters that breathe. . . . Between the Sheets did what great books should do and let me live beside these people of Bishop and come to care about them. A lot.”—The Best Reviews “An intense, heartbreaking and poignant novel that is also insanely hot and incredibly passionate . . . another powerful novel of love and healing by Molly O’Keefe that old and new fans of the Boys of Bishop series do not want to miss.”—Book Reviews & More by Kathy

Raven Flight

Author : Juliet Marillier
Publisher : Ember
Page : 418 pages
File Size : 14,52 MB
Release : 2014-07-08
Category : Young Adult Fiction
ISBN : 0375871977

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Neryn has finally found the rebel group at Shadowfell, and now her task is to seek out the elusive Guardians, vital to her training as a Caller. These four powerful beings have been increasingly at odds with human kind, and Neryn must prove her worth to them. She desperately needs their help to use her gift without compromising herself or the cause of overthrowing the evil King Keldec. Neryn must journey with the tough and steadfast Tali, who looks on Neryn's love for the double agent Flint as a needless vulnerability. And perhaps it is. What Flint learns from the king will change the battlefield entirely—but in whose favor, no one knows.

Sheltering Rain

Author : Jojo Moyes
Publisher : Harper Collins
Page : 298 pages
File Size : 43,77 MB
Release : 2013-07-16
Category : Fiction
ISBN : 1443428140

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From the #1 New York Times bestselling author of Me Before You, the basis for the major motion picture, comes the touching, unforgettable story of three generations of Irish women faced with the fundamental truths of love, duty, and the unbreakable bond that unites mothers and daughters. Estranged from her mother since she ran away from her rural Irish home as a young woman, Kate swore a future oath that she’d always be a friend to her daughter, Sabine. But history has a way of repeating itself, and Kate now faces an ever-widening chasm between herself and her daughter. With Sabine about to make her own journey to Ireland to see the grandmother Kate abandoned, Kate is left wondering how they ever made it here, and what she can do to close the gap between them. For Joy, seeing her granddaughter is a dream come true. After the painful separation from Kate, she’s looking forward to having time with Sabine. Yet almost as soon as the young woman arrives, the lack of common ground between them deflates her enthusiasm. And when Sabine’s impetuous, inquisitive nature forces Joy to face long-buried secrets from her past, she realizes that perhaps it’s time to finally heal old wounds. “This perceptive…novel does the mother-and-daughter thing in page-turning style.”--Elle

Hope

Author : Lesley Pearse
Publisher : Michael Joseph
Page : 0 pages
File Size : 11,66 MB
Release : 2010
Category : Crimean War, 1853-1856
ISBN : 9780141046105

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Smuggled away from the rich Harvey household to a nearby village, Hope grows up in the arms of the warm and loving Renton family. But her idyllic childhood comes to an end when she is taken into service by the Harveys, setting in motion a chain of events that will see her blackmailed into leaving her beloved family for ever.

A History of World Agriculture

Author : Marcel Mazoyer
Publisher : NYU Press
Page : 528 pages
File Size : 24,60 MB
Release : 2006-06
Category : Business & Economics
ISBN : 1583671218

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Only once we understand the long history of human efforts to draw sustenance from the land can we grasp the nature of the crisis that faces humankind today, as hundreds of millions of people are faced with famine or flight from the land. From Neolithic times through the earliest civilizations of the ancient Near East, in savannahs, river valleys and the terraces created by the Incas in the Andean mountains, an increasing range of agricultural techniques have developed in response to very different conditions. These developments are recounted in this book, with detailed attention to the ways in which plants, animals, soil, climate, and society have interacted. Mazoyer and Roudart’s A History of World Agriculture is a path-breaking and panoramic work, beginning with the emergence of agriculture after thousands of years in which human societies had depended on hunting and gathering, showing how agricultural techniques developed in the different regions of the world, and how this extraordinary wealth of knowledge, tradition and natural variety is endangered today by global capitialism, as it forces the unequal agrarian heritages of the world to conform to the norms of profit. During the twentieth century, mechanization, motorization and specialization have brought to a halt the pattern of cultural and environmental responses that characterized the global history of agriculture until then. Today a small number of corporations have the capacity to impose the farming methods on the planet that they find most profitable. Mazoyer and Roudart propose an alternative global strategy that can safegaurd the economies of the poor countries, reinvigorate the global economy, and create a livable future for mankind.