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Interpretation and Extrapolation of Chemical and Biological Carcinogenicity Data to Establish Human Safety Standards

Author : H.C. Grice
Publisher : Springer Science & Business Media
Page : 200 pages
File Size : 32,63 MB
Release : 2012-12-06
Category : Medical
ISBN : 3642493718

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The International Life Sciences Institute (lLSI) is a scientific foundation wh ich addresses critical health and safety issues of national and international concern. ILSI promotes international cooperation by pro viding the mechanism for scientists from government, industry and universities to work together on cooperative programs to generate and disseminate scientific data. The members and trustees of the Institute believe that questions regarding health and safety are best resolved when scientists can ex amine and discuss issues, as an independent body, se~arate from the political pressures of individual countries and the economic concerns of individual companies. Frequently, meaningful assessment of the risk of a test substance is hindered by the inherent inconsistencies in the system. The development and refinement of methods and systems to evaluate the safety of chemicals have evolved in a rapid and largely unplanned fashion. Attempts to improve the system have largely been directed toward broad general concerns, with little attention being given to specific problems or issues. A failure to resolve these problems has frequently resulted in increased testing costs and complications in the assessment and extrapolation of the results. Publicity surrounding toxicologic issues has created chronic public apprehension about the ability of science and government to deal effectively with these problems. In response to these difficulties, ILSI has assembled highly qualified and renowned scientists from research institutes, universities, government and industry, with relevant scientific knowledge and expertise regarding the issues that complicate risk assessment procedures.

ILAR News

Author : Institute of Laboratory Animal Resources (U.S.)
Publisher :
Page : 326 pages
File Size : 16,98 MB
Release : 1984
Category : Electronic journals
ISBN :

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Information Resources in Toxicology

Author : P.J. Bert Hakkinen
Publisher : Elsevier
Page : 953 pages
File Size : 43,67 MB
Release : 2000-01-10
Category : Medical
ISBN : 008053466X

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Information Resources in Toxicology, Third Edition is a sourcebook for anyone who needs to know where to find toxicology information. It provides an up-to-date selective guide to a large variety of sources--books, journals, organizations, audiovisuals, internet and electronic sources, and more. For the Third Edition, the editors have selected, organized, and updated the most relevant information available. New information on grants and other funding opportunities, physical hazards, patent literature, and technical reports have also been added.This comprehensive, time-saving tool is ideal for toxicologists, pharmacologists, drug companies, testing labs, libraries, poison control centers, physicians, legal and regulatory professionals, and chemists. Serves as an all-in-one resource for toxicology information New edition includes information on publishers, grants and other funding opportunities, physical hazards, patent literature, and technical reports Updated to include the latest internet and electronic sources, e-mail addresses, etc. Provides valuable data about the new fields that have emerged within toxicological research; namely, the biochemical, cellular, molecular, and genetic aspects

Current Catalog

Author : National Library of Medicine (U.S.)
Publisher :
Page : 1712 pages
File Size : 41,58 MB
Release : 1985
Category : Medicine
ISBN :

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First multi-year cumulation covers six years: 1965-70.

Drinking Water and Health, Volume 8

Author : National Research Council
Publisher : National Academies Press
Page : 507 pages
File Size : 34,50 MB
Release : 1987-02-01
Category : Nature
ISBN : 0309037751

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Pharmacokinetics, the study of the movement of chemicals within the body, is a vital tool in assessing the risk of exposure to environmental chemicals. This bookâ€"a collection of papers authored by experts in academia, industry, and governmentâ€"reviews the progress of the risk-assessment process and discusses the role of pharmacokinetic principles in evaluating risk. In addition, the authors discuss software packages used to analyze data and to build models simulating biological phenomena. A summary chapter provides a view of trends in pharmacokinetic modeling and notes some prospective fields of study.