[PDF] Insulin The Crooked Timber eBook

Author : Kersten T. Hall
Publisher : Oxford University Press
Page : 476 pages
File Size : 37,9 MB
Release : 2022
Category : Medical
ISBN : 0192855387

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Before the discovery of insulin, a diagnosis of Type 1 diabetes was a death sentence. To mark the centenary of this landmark in medicine, this book charts the journey of how insulin was transformed from what one clinician called 'thick brown muck' into the very first drug to be produced using genetic engineering, and which earned the founders of US biotech company Genentech a small fortune. Taking the reader on a fascinating journey, starting with the discovery of insulin in the 1920s through to the present day, Insulin - The Crooked Timber reveals a story of monstrous egos, toxic career rivalries, and a few unsung heroes and heroines. It discusses in detail the circumstances of Canadian scientist Frederick Banting whose award of the 1923 Nobel Prize for this life-saving discovery proved to be both a blessing and a curse for him and explores how the human story behind this discovery still remains one of ongoing political and scientific controversy. The book is the result of the author's own shocking diagnosis with Type 1 diabetes and its story reminds us all of what technology can - and cannot do - for us. As the world struggles to emerge from the COVID-19 pandemic and face future challenges such as climate change, the lessons that we can learn from the story of insulin have never been more important.

Author : Mike Konczal
Publisher : The New Press
Page : 258 pages
File Size : 34,51 MB
Release : 2021-02-02
Category : Social Science
ISBN : 1620975386

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The progressive economics writer redefines the national conversation about American freedom “Mike Konczal [is] one of our most powerful advocates of financial reform‚ [a] heroic critic of austerity‚ and a huge resource for progressives.”—Paul Krugman Health insurance, student loan debt, retirement security, child care, work-life balance, access to home ownership—these are the issues driving America’s current political debates. And they are all linked, as this brilliant and timely book reveals, by a single question: should we allow the free market to determine our lives? In the tradition of Naomi Klein’s The Shock Doctrine, noted economic commentator Mike Konczal answers this question with a resounding no. Freedom from the Market blends passionate political argument and a bold new take on American history to reveal that, from the earliest days of the republic, Americans have defined freedom as what we keep free from the control of the market. With chapters on the history of the Homestead Act and land ownership, the eight-hour work day and free time, social insurance and Social Security, World War II day cares, Medicare and desegregation, free public colleges, intellectual property, and the public corporation, Konczal shows how citizens have fought to ensure that everyone has access to the conditions that make us free. At a time when millions of Americans—and more and more politicians—are questioning the unregulated free market, Freedom from the Market offers a new narrative, and new intellectual ammunition, for the fight that lies ahead.

Author : Michael Bliss
Publisher : University of Toronto Press
Page : 320 pages
File Size : 40,65 MB
Release : 2017-06-22
Category : Medical
ISBN : 1487516746

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The discovery of insulin at the University of Toronto in 1921-22 was one of the most dramatic events in the history of the treatment of disease. Insulin was a wonder-drug with ability to bring patients back from the very brink of death, and it was no surprise that in 1923 the Nobel Prize for Medicine was awarded to its discoverers, the Canadian research team of Banting, Best, Collip, and Macleod. In this engaging and award-winning account, historian Michael Bliss recounts the fascinating story behind the discovery of insulin – a story as much filled with fiery confrontation and intense competition as medical dedication and scientific genius. Originally published in 1982 and updated in 1996, The Discovery of Insulin has won the City of Toronto Book Award, the Jason Hannah Medal of the Royal Society of Canada, and the William H. Welch Medal of the American Association for the History of Medicine.

Author : Arleen Marcia Tuchman
Publisher : Yale University Press
Page : 287 pages
File Size : 13,83 MB
Release : 2020-08-05
Category : Health & Fitness
ISBN : 0300228996

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Who gets diabetes and why? An in-depth examination of diabetes in the context of race, public health, class, and heredity Who is considered most at risk for diabetes, and why? In this thorough, engaging book, historian Arleen Tuchman examines and critiques how these questions have been answered by both the public and medical communities for over a century in the United States. Beginning in the late nineteenth century, Tuchman describes how at different times Jews, middle-class whites, American Indians, African Americans, and Hispanic Americans have been labeled most at risk for developing diabetes, and that such claims have reflected and perpetuated troubling assumptions about race, ethnicity, and class. She describes how diabetes underwent a mid-century transformation in the public's eye from being a disease of wealth and "civilization" to one of poverty and "primitive" populations. In tracing this cultural history, Tuchman argues that shifting understandings of diabetes reveal just as much about scientific and medical beliefs as they do about the cultural, racial, and economic milieus of their time.

Author : Thea Cooper
Publisher : Macmillan + ORM
Page : 319 pages
File Size : 46,28 MB
Release : 2010-09-14
Category : Medical
ISBN : 142996569X

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It is 1919 and Elizabeth Hughes, the eleven-year-old daughter of America's most-distinguished jurist and politician, Charles Evans Hughes, has been diagnosed with juvenile diabetes. It is essentially a death sentence. The only accepted form of treatment – starvation – whittles her down to forty-five pounds skin and bones. Miles away, Canadian researchers Frederick Banting and Charles Best manage to identify and purify insulin from animal pancreases – a miracle soon marred by scientific jealousy, intense business competition and fistfights. In a race against time and a ravaging disease, Elizabeth becomes one of the first diabetics to receive insulin injections – all while its discoverers and a little known pharmaceutical company struggle to make it available to the rest of the world. Relive the heartwarming true story of the discovery of insulin as it's never been told before. Written with authentic detail and suspense, and featuring walk-ons by William Howard Taft, Woodrow Wilson, and Eli Lilly himself, among many others.

Author : Kersten T. Hall
Publisher : Oxford University Press (UK)
Page : 255 pages
File Size : 35,53 MB
Release : 2014
Category : Biography & Autobiography
ISBN : 0198704593

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Tells the story of the English physicist and molecular biologist William T. Astbury and how his work forms a previously untold chapter in the story of the discovery of the structure of DNA.

Author : Stuart Bradwel
Publisher : John Wiley & Sons
Page : 199 pages
File Size : 21,73 MB
Release : 2023-06-08
Category : Science
ISBN : 1509550739

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In 1922, an unlikely team of researchers in Toronto made one of the most important medical breakthroughs of the century: insulin. Their discovery seemed miraculous. When it was given to diabetic patients on the brink of death, their condition rapidly improved. Those present could barely believe their eyes: they had witnessed resurrection. However, this was no simple cure. Injections must be taken for life. Without them, symptoms quickly return, often with fatal results. But while a lifetime on insulin poses great challenges, it also offers opportunities. In this revelatory history, Stuart Bradwel looks back on one of medicine’s most celebrated innovations. Setting professional narrative against subjective patient experience, he tells the story of a drug that has challenged many of the basic assumptions upon which medical practice is built, both inside and outside the clinic. Nevertheless, Bradwel reminds us that the centenary of this apparent “wonder drug” should be no cause for celebration. Insulin often remains inaccessible to those who need it most: elusive prescriptions, uneven availability and sky-high prices result in rationing and desperate do-it-yourself research and development. In the face of bootstraps rhetoric and “Pharma Bro” capitalists, patients across the world are left to fend for themselves. There is a long way to go in the twenty-first century until insulin truly fulfils the extraordinary promises made by its discovery.

Author : Kieran Healy
Publisher : University of Chicago Press
Page : 208 pages
File Size : 25,62 MB
Release : 2010-08-15
Category : Social Science
ISBN : 0226322386

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More than any other altruistic gesture, blood and organ donation exemplifies the true spirit of self-sacrifice. Donors literally give of themselves for no reward so that the life of an individual—often anonymous—may be spared. But as the demand for blood and organs has grown, the value of a system that depends solely on gifts has been called into question, and the possibility has surfaced that donors might be supplemented or replaced by paid suppliers. Last Best Gifts offers a fresh perspective on this ethical dilemma by examining the social organization of blood and organ donation in Europe and the United States. Gifts of blood and organs are not given everywhere in the same way or to the same extent—contrasts that allow Kieran Healy to uncover the pivotal role that institutions play in fashioning the contexts for donations. Procurement organizations, he shows, sustain altruism by providing opportunities to give and by producing public accounts of what giving means. In the end, Healy suggests, successful systems rest on the fairness of the exchange, rather than the purity of a donor’s altruism or the size of a financial incentive.

Author : Hasok Chang
Publisher : Oxford University Press
Page : 305 pages
File Size : 27,36 MB
Release : 2004-08-05
Category : Science
ISBN : 0199883696

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What is temperature, and how can we measure it correctly? These may seem like simple questions, but the most renowned scientists struggled with them throughout the 18th and 19th centuries. In Inventing Temperature, Chang examines how scientists first created thermometers; how they measured temperature beyond the reach of standard thermometers; and how they managed to assess the reliability and accuracy of these instruments without a circular reliance on the instruments themselves. In a discussion that brings together the history of science with the philosophy of science, Chang presents the simple eet challenging epistemic and technical questions about these instruments, and the complex web of abstract philosophical issues surrounding them. Chang's book shows that many items of knowledge that we take for granted now are in fact spectacular achievements, obtained only after a great deal of innovative thinking, painstaking experiments, bold conjectures, and controversy. Lurking behind these achievements are some very important philosophical questions about how and when people accept the authority of science.

Author : William C. Scott
Publisher : UPNE
Page : 441 pages
File Size : 27,50 MB
Release : 2012-01-15
Category : Literary Criticism
ISBN : 1611682290

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An examination of the aesthetic qualities of the Homeric simile