[PDF] Immunological Mechanisms In Asthma And Allergic Diseasesvol 78 Chemi eBook

Author : Douglas S. Robinson
Publisher : Karger Medical and Scientific Publishers
Page : 227 pages
File Size : 40,30 MB
Release : 2000-01-01
Category : Medical
ISBN : 3805571127

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This book explores the cellular and molecular mechanisms involved in asthma and allergic diseases, from basic immunology to the treatment of patients. Arising from a special symposium held to celebrate Professor A. Barry Kay's 20th anniversary as Head of the Department of Allergy and Clinical Immunology at the National Heart and Lung Institute, London, the publication presents 18 review articles by an impressive cross section of experts in the field. Topics considered include Th1 and Th2 cells, the regultion of Th2 cytokine transcription, the role of T cells in the immunopathogenesis of asthma, and MHC-restricted IgE-independent T-cell-induced late-phase responses in human subjects. Further chapters focus on eosinophil adhesion and activation, the role of C-C chemokines in the recruitment of eosinophils, and the interactions between eosinophils and fibroblasts. T-cell recruitment and T-cell interactions in cutaneous basophil hypersensitivity and fibrotic lung disease are discussed, as is the molecular pathology of allergic disease. Finally, treatment approaches are considered in chapters on the molecular basis of corticosteroid actions in asthma, immunosuppression in asthma, and immunotherapy of allergic diseases.

Author : Burton Zweiman
Publisher : CRC Press
Page : 604 pages
File Size : 50,99 MB
Release : 2023-01-06
Category : Medical
ISBN : 1000893766

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Contains patterns of allergic reactivity for disorders such as asthma, atopic dermatitis, urticaria, and anaphylaxis. Written by leading experts in the field, Inflammatory Mechanisms in Allergic Diseases covers non-anaphylactic drug disorders; synthesis and formation of IgE antibodies; new treatments using allergenic peptides, immunostimulatory oligonucleotides, and pharmacogenomics;recent advances targeting effector mechanisms; hypersensitivity reactions to drugs and more! With over 3100 references, tables, drawings, and micrographs, Inflammatory Mechanisms in Allergic Diseases is an essential reference for allergists, pulmonologists, immunologists, dermatologists, ophthalmologists, otolaryngologists, internists, pediatricians, family practitioners, and medical students in these disciplines.

Author : Seyyed Shamsadin Athari
Publisher : Elsevier
Page : 210 pages
File Size : 29,74 MB
Release : 2024-05-29
Category : Science
ISBN : 0443155038

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Asthma is a chronic complicated airway disease whose mortality and morbidity rates have increased worldwide. Some common treatments for asthma cannot control it nor even prevent simple inflammation and relieve shortness of breath, so understanding its molecular pathways and pathophysiology is required in order to better understand the disease and to diagnose, control and treat it. Allergic Asthma Immunopathogenesis: Immunopathology of the Allergic Asthma presents a new glance to the allergic asthma pathophysiology by focusing on the immunopathogenesis and allergo-inflammation mechanisms of asthma and cell signaling pathways that can be used for various research purposes, including the design of anti-asthma treatment and target therapy for scientists and researchers. Covers new molecular pathophysiology mechanisms and cell signaling pathways in pathogenesis of allergic asthma that have been introduced in recent research Discusses immunologic basis of the allergy and hyperresponsiveness Includes results of recent research focusing on the diagnosis and treatment of allergic asthma

Author : Gianni Marone
Publisher : Elsevier
Page : 478 pages
File Size : 47,96 MB
Release : 1998-05-01
Category : Science
ISBN : 0080527647

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This book updates the previous coverage of the mechanisms and mediators of asthma and its treatment. It presents articles by the foremost names in the field. Updates the previous coverage of the mechanisms and mediators of asthma and its treatment Presents articles by the foremost names in the field Includes over 92 figures and 12 tables

Author : Elisabeth Heseltine
Publisher : WHO Regional Office Europe
Page : 247 pages
File Size : 14,83 MB
Release : 2009
Category : Architecture
ISBN : 9289041684

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Microbial pollution is a key element of indoor air pollution. It is caused by hundreds of species of bacteria and fungi, in particular filamentous fungi (mould), growing indoors when sufficient moisture is available. This document provides a comprehensive review of the scientific evidence on health problems associated with building moisture and biological agents. The review concludes that the most important effects are increased prevalences of respiratory symptoms, allergies and asthma as well as perturbation of the immunological system. The document also summarizes the available information on the conditions that determine the presence of mould and measures to control their growth indoors. WHO guidelines for protecting public health are formulated on the basis of the review. The most important means for avoiding adverse health effects is the prevention (or minimization) of persistent dampness and microbial growth on interior surfaces and in building structures. [Ed.]

Author : Andrew Kiboneka
Publisher :
Page : 0 pages
File Size : 42,38 MB
Release : 2020
Category : Electronic books
ISBN :

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The immune system is a complex collection of cells, tissues, and chemical mediators positioned throughout the body, whose primary purpose is to protect us against infection. However, its function is not only fundamental in protection from infectious disease but also provides aberrant response in allergens such as with asthma and allergic rhinitis. Allergic diseases like asthma and allergic rhinitis are characterized by a distinct type of inflammatory response, driven by immunoglobulin E (IgE)-dependent mechanisms. In asthma and allergic rhinitis, the inflammatory response is mediated by interaction of several immune cells (monocytes, lymphocytes, and polymorphonuclear cells) and cellular chemical mediators. In particular, atopic allergic response leads to destruction of multiple target cells such as epithelial, parenchymal and vascular and connective tissue of the airways. In addition, in inflammatory response in asthma and allergic rhinitis, sensory nerves are sensitized, leading to clinical manifestations. Sneezing and coughing are hypersensitivity responses of sensory nerves in allergic rhinitis and asthma, respectively. Similarly, nasal congestion and discharge in allergic rhinitis are due to vasodilatation that leads to plasma exudates as well as mucous secretion. The allergic inflammatory response is regulated by several transcription factors, particularly nuclear factor-κb (NF-κB), GATA-3 protein 3, and GATA binding protein.