[PDF] Helicobacter Pylori In The 21st Century eBook

Author : Philip Sutton
Publisher : CABI
Page : 316 pages
File Size : 13,81 MB
Release : 2010
Category : Medical
ISBN : 1845935942

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This book provides a broad overview of the current understanding of Helicobacter pylori emphasizing its world health impacts. It includes 13 chapters organized into 3 parts: "Pathologies and Treatment", "Host Response" and "Bacterial Defence". Part I (5 chapters) reviews the epidemiology of H. pylori infection, H. pylori infection in Asia, gastric adenocarcinoma, antimicrobial resistance and approaches to treatment, and extragastric manifestations of H. pylori infection. Part II (4 chapters) describes H. pylori-induced acquired immunity and immunoregulation, host genetic factors and susceptibility to H. pylori pathogenesis, innate immune initiators and effectors in H. pylori infection, and H. pylori vaccines. Part III (4 chapters) discusses the importance of H. pylori lipopolysaccharides in gastric adaptation and pathogenesis, H. pylori virulence factors, H. pylori adhesion to the gastric surface, and helicobacteromics. This book is an essential resource for researchers, students and medics in infectious and Helicobacter-associated diseases.

Author : Philip Sutton
Publisher :
Page : 0 pages
File Size : 49,68 MB
Release :
Category : Medical
ISBN : 9781845935948

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This book provides a broad overview of the current understanding of Helicobacter pylori emphasizing its world health impacts. It includes 13 chapters organized into 3 parts: "Pathologies and Treatment", "Host Response" and "Bacterial Defence". Part I (5 chapters) reviews the epidemiology of H. pylori infection, H. pylori infection in Asia, gastric adenocarcinoma, antimicrobial resistance and approaches to treatment, and extragastric manifestations of H. pylori infection. Part II (4 chapters) describes H. pylori-induced acquired immunity and immunoregulation, host genetic factors and susceptibility to H. pylori pathogenesis, innate immune initiators and effectors in H. pylori infection, and H. pylori vaccines. Part III (4 chapters) discusses the importance of H. pylori lipopolysaccharides in gastric adaptation and pathogenesis, H. pylori virulence factors, H. pylori adhesion to the gastric surface, and helicobacteromics. This book is an essential resource for researchers, students and medics in infectious and Helicobacter-associated diseases.

Author : Giovanni Gasbarrini
Publisher : Springer Science & Business Media
Page : 333 pages
File Size : 27,70 MB
Release : 2012-12-06
Category : Medical
ISBN : 3642782310

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A century ago the Italian pathologist Bizzozero described the relationships between spiral bacteria and the mammalian gastro intestinal tract. Since 1982, when Helicobacter pylori was discovered, gastroduodenal disease have been completely revised as a con sequence of the results of basic and clinical research in this field. Progress in understanding the pathogenesis of this bacterium has been made by studying H. pylori infection in animal models. More specific diagnostic tools have been developed using new molecular biology techniques. Future trends are directed towards preparing a specific H. pylori vaccine. A new classification for gastritis, the Sydney System, including H. pylori gastritis, was proposed in 1990. As concerns the clinical approach to peptic ulcer disease in the 1990's, the majority of authors agree on the importance of H. pylori eradication. Moreover, recent clinical studies suggest that H. pylori infection can be associated with other gastroduodenal diseases, such as non ulcer dyspepsia and gastric cancer. Multicenter trials to standardize serological methods and evaluate the efficacy of new antimicrobial therapy schedules are planned throughout different European countries. The fourth Workshop of the European Helicobacter Pylori Study Group was held in Bologna, Italy, in November 1991. Two years before Bologna University celebrated its ninth centennial, giving evidence of being the oldest University in the modern world. Thus the H. pylori story that has continued for more than a century has been discussed once again at the University with the oldest tradition in the world.

Author : Institute of Medicine
Publisher : National Academies Press
Page : 472 pages
File Size : 37,93 MB
Release : 2001-02-21
Category : Medical
ISBN : 0309174988

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Vaccines have made it possible to eradicate the scourge of smallpox, promise the same for polio, and have profoundly reduced the threat posed by other diseases such as whooping cough, measles, and meningitis. What is next? There are many pathogens, autoimmune diseases, and cancers that may be promising targets for vaccine research and development. This volume provides an analytic framework and quantitative model for evaluating disease conditions that can be applied by those setting priorities for vaccine development over the coming decades. The committee describes an approach for comparing potential new vaccines based on their impact on morbidity and mortality and on the costs of both health care and vaccine development. The book examines: Lessons to be learned from the polio experience. Scientific advances that set the stage for new vaccines. Factors that affect how vaccines are used in the population. Value judgments and ethical questions raised by comparison of health needs and benefits. The committee provides a way to compare different forms of illness and set vaccine priorities without assigning a monetary value to lives. Their recommendations will be important to anyone involved in science policy and public health planning: policymakers, regulators, health care providers, vaccine manufacturers, and researchers.

Author : Philip Sutton
Publisher : CABI
Page : 318 pages
File Size : 27,77 MB
Release : 2010
Category : Medical
ISBN : 1845935950

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Helicobacter pylori is a globally significant pathogen that infects half of the population of the world. Providing a broad overview of the understanding of this pathogen, this book explores a range of topics including virulence factors, vaccine development and obstacles, epidemiology, antibiotic resistance and the role of Nod receptors.

Author : Bruna Maria Roesler
Publisher : BoD – Books on Demand
Page : 136 pages
File Size : 36,68 MB
Release : 2019-09-18
Category : Science
ISBN : 183881146X

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Helicobacter pylori is an universally distributed bacterium which affects more than half of the world population. H. pylori infection causes persistent inflammation with different clinical outcomes in humans, including chronic gastritis, peptic ulcer disease and gastric cancer. The infection has also been associated with several extradigestive disorders. In this book there is a comprehensive overview of contributors on H. pylori infection in diverse areas, including virulence factors of H. pylori and their importance for the clinical outcome of the diseases, discussions about the principal therapeutic regimens of bacterium eradication, also considering the antimicrobial resistance. H. pylori is clearly a very interesting bacteria and great studies and discussions about all its aspects are welcome to the medical and scientific communities.

Author : Shigeru Kamiya
Publisher : Springer Nature
Page : 284 pages
File Size : 37,30 MB
Release : 2019-10-22
Category : Medical
ISBN : 303021916X

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This book gathers a wealth of contributions on the virulence factors and pathogenic mechanism of Helicobacter pylori, prepared by leading international experts. In addition, it explores the epidemiology, diagnosis, treatment with drugs and probiotics, and prophylaxis by vaccination, reflecting the latest advances. H. pylori is a Gram negative microaerophilic bacterium that can produce various gastric diseases including gastritis, gastroduodenal ulceration, gastric cancer and gastric MALT lymphoma. Although efforts to combat H. pylori using a combination of proton pump inhibitor and several antimicrobial drugs have significantly decreased the burden of these gastric diseases, the microbial epidemiology and gastric pathogenesis following H. pylori infection are still not fully understood. Given its scope, the book offers a valuable resource not only for basic microbiologists, but also for researchers in the fields of pathology, biochemistry and genomics, as well as medical students/scientists.

Author : Bruna Maria Roesler
Publisher : BoD – Books on Demand
Page : 394 pages
File Size : 11,57 MB
Release : 2014-04-03
Category : Medical
ISBN : 9535112392

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Helicobacter pylori is a universally distributed bacterium which affects more than half of the world population. The infection is associated with the development of various diseases of the upper gastrointestinal tract, besides extradigestive diseases. This book is a comprehensive overview of contributors on H. pylori infection in several areas. Its chapters were divided into sections concerning general aspects of H. pylori infection, immunopathology and genetic diversity, questions regarding possible routes of bacterium transmission, the importance of the strains characteristics in the development of gastric cancer and the possibilities of prevention, H. pylori infection in children, the possible association between its infection and extradigestive diseases, and the principal therapeutic regimens of bacterium eradication, considering the antimicrobial resistance.

Author : Buzás György Miklós
Publisher : Bentham Science Publishers
Page : 526 pages
File Size : 46,74 MB
Release : 2014-03-12
Category : Medical
ISBN : 1608057372

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This e-book covers Helicobacter pylori research as it looks in 2014. The discovery of the bacterium in 1982 by B.J. Marshall and R. I. Warren had a tremendous impact on basic research and clinical medicine, resulting, in the past 3 decades, in more than 34,000 published articles. The editor of this volume and the contributing authors have compiled a unique collection of chapters dealing the with the microbiology, epidemiology, clinical diagnosis and treatment of H. pylori infections in a country-specific manner, with contributors having the opportunity to present the peculiarities and specifics of Helicobacter research in their area or country without overlapping any other previously published e-book. This e-book is a useful reference for gastrointestinal physicians and medical researchers seeking the latest information related to H. pylori.

Author : C. Scarpignato
Publisher : Karger Medical and Scientific Publishers
Page : 482 pages
File Size : 20,74 MB
Release : 1999-01-01
Category : Medical
ISBN : 3805564511

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There are few areas in medical science where the information explosion exceeds the capacity for a busy clinician to keep up to date. One such area is Helicobacter pylori. Since the first paper identifying H. pylori was published in 1983, great progress has occurred concerning H. pylori and its causal relationship to gastritis, duodenal ulcer, gastric ulcer and gastric cancer. In a field which is moving so fast, a lot of new information is continuously reported at medical meetings, often published only in abstract form, without further appearing in peer-reviewed journals. Even gastroenterologists, unless actively involved in the field of H. pylori research themselves, find it difficult to keep abreast of the field. Although several volumes and monographs have appeared on H. pylori, this book is the only one entirely devoted to the clinical pharmacology and therapy of the Helicobacter infection. It is clear that the real-world indications for H. pylori treatment are being broadened, and it is impossible to turn back the tide of prescribing by primary care physicians or gastroenterologists. Some effective and safe eradication regimens are available today but several new ones, often simple variations of an old scheme, are being proposed as equally effective and safe. This volume, which covers the treatment of all the H. pylori-related digestive diseases as well as the management of treatment failure and reinfection, will be a valuable reference text for all those physicians who pursue the cure of this common human infection.