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Regulation of Tissue Oxygenation, Second Edition

Author : Roland N. Pittman
Publisher : Biota Publishing
Page : 117 pages
File Size : 27,10 MB
Release : 2016-08-18
Category : Medical
ISBN : 1615047212

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This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.

Heart and Blood

Author : Richard Nelson
Publisher : Vintage
Page : 428 pages
File Size : 45,3 MB
Release : 1998-09-29
Category : Nature
ISBN :

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Examines the physiology of deer, and describes how they have had to adapt to man's encroachment on their natural environments in varied parts of the United States.

Regulation of Coronary Blood Flow

Author : Michitoshi Inoue
Publisher : Springer Science & Business Media
Page : 330 pages
File Size : 46,50 MB
Release : 2013-11-09
Category : Medical
ISBN : 4431683674

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Research centering on blood flow in the heart continues to hold an important position, especially since a better understanding of the subject may help reduce the incidence of coronary arterial disease and heart attacks. This book summarizes recent advances in the field; it is the product of fruitful cooperation among international scientists who met in Japan in May, 1990 to discuss the regulation of coronary blood flow.

Heart's Blood

Author : Juliet Marillier
Publisher : Penguin
Page : 416 pages
File Size : 38,72 MB
Release : 2009-11-03
Category : Fiction
ISBN : 1101149248

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National bestselling author Juliet Marillier revisits the classic fairy tale of Beauty and the Beast in this “engaging Gaelic fantasy romance staring two fascinating reluctant souls”(Genre Go Round Reviews). Whistling Tor is a place of secrets, a mysterious, wooded hill housing the crumbling fortress belonging to Anluan—a chieftain whose name is spoken throughout the region in tones of revulsion and bitterness. A curse lies over Anluan’s family and his people, and the woods themselves hold a perilous force whose every whisper threatens doom. Then the young scribe Caitrin appears in Anluan’s garden, admiring the rare plant known as heart’s blood. Retained to sort through entangled family documents, Caitrin brings about unexpected changes in the household, casting a hopeful light against the despairing shadows. But even as Caitrin brings solace to Anluan, and the promise of something more between them, he remains in thrall to the darkness surrounding Whistling Tor. To free Anluan’s burdened soul, Caitrin must unravel the web of sorcery woven by his ancestors before it claims his life—and their love...

Control of Cardiac Output

Author : David Young
Publisher : Biota Publishing
Page : 110 pages
File Size : 34,16 MB
Release : 2010-01-01
Category : Medical
ISBN : 1615040226

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Although cardiac output is measured as the flow of blood from the left ventricle into the aorta, the system that controls cardiac output includes many other components besides the heart itself. The heart’s rate of output cannot exceed the rate of venous return to it, and therefore, the factors governing venous return are primarily responsible for control of output from the heart. Venous return is affected by its pressure gradient and resistance to flow throughout the vascular system. The pressure gradient for venous return is a function of several factors including the blood volume flowing through the system, the unstressed vascular volume of the circulatory system, its capacitance, mean systemic pressure, and right atrial pressure. Resistance to venous return is the sum of total vascular resistance from the aortic valve to the right atrium. The sympathetic nervous system and vasoactive circulating hormones affect short-term resistance, whereas local tissue blood flow autoregulatory mechanisms are the dominant determinants of long-term resistance to venous return. The strength of contraction of the heart responds to changes in atrial pressure driven by changes in venous return, with small changes in atrial pressure eliciting large changes in strength of contraction, as described by the Frank–Starling mechanism. In addition, the autonomic nervous system input to the heart alters myocardial pumping ability in response to cardiovascular challenges. The function of the cardiovascular system is strongly affected by the operation of the renal sodium excretion–body fluid volume–arterial pressure negative feedback system that maintains arterial blood pressure at a controlled value over long periods. The intent of this volume is to integrate the basic knowledge of these cardiovascular system components into an understanding of cardiac output regulation. Table of Contents: Introduction / Venous Return / Cardiac Function / Integrated Analysis of Cardiac Output Control / Analysis of Cardiac Output Regulation by Computer Simulation / Analysis of Cardiac Output Control in Response to Challenges / Conclusion / References / Author Biography

Hematology

Author : Ronald Hoffman
Publisher :
Page : 2821 pages
File Size : 22,29 MB
Release : 2005
Category : Blood
ISBN : 9780443066283

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Circulation of the Blood

Author : Alfred P. Fishman
Publisher : Springer
Page : 871 pages
File Size : 13,64 MB
Release : 2013-05-26
Category : Medical
ISBN : 1461475465

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Capturing the real spirit of creativity in physiology, this book explores the personal elements involved in scientific discovery. Circulation of the Blood is the story of the people and achievements that have changed the way we've come to view the human body. The authors, renowned for their extensive experience in the field, examine the heritage of creative genius involved in physiology and trace the historical development of ideas relating to various aspects of circulation of the blood. Their comprehensive coverage goes from the early discoveries of the Greeks and Romans up to modern times.

An Anatomical Disquisition on the Motion of the Heart & Blood in Animals

Author : William Harvey
Publisher : Good Press
Page : 208 pages
File Size : 32,40 MB
Release : 2022-08-21
Category : Fiction
ISBN :

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"An Anatomical Disquisition on the Motion of the Heart & Blood in Animals" by William Harvey (translated by Robert Willis). Published by Good Press. Good Press publishes a wide range of titles that encompasses every genre. From well-known classics & literary fiction and non-fiction to forgotten−or yet undiscovered gems−of world literature, we issue the books that need to be read. Each Good Press edition has been meticulously edited and formatted to boost readability for all e-readers and devices. Our goal is to produce eBooks that are user-friendly and accessible to everyone in a high-quality digital format.

Caffeine in Food and Dietary Supplements

Author : Leslie A. Pray
Publisher :
Page : 0 pages
File Size : 43,7 MB
Release : 2014
Category : Health & Fitness
ISBN : 9780309297493

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Caffeine in Food and Dietary Supplements is the summary of a workshop convened by the Institute of Medicine in August 2013 to review the available science on safe levels of caffeine consumption in foods, beverages, and dietary supplements and to identify data gaps. Scientists with expertise in food safety, nutrition, pharmacology, psychology, toxicology, and related disciplines; medical professionals with pediatric and adult patient experience in cardiology, neurology, and psychiatry; public health professionals; food industry representatives; regulatory experts; and consumer advocates discussed the safety of caffeine in food and dietary supplements, including, but not limited to, caffeinated beverage products, and identified data gaps. Caffeine, a central nervous stimulant, is arguably the most frequently ingested pharmacologically active substance in the world. Occurring naturally in more than 60 plants, including coffee beans, tea leaves, cola nuts and cocoa pods, caffeine has been part of innumerable cultures for centuries. But the caffeine-in-food landscape is changing. There are an array of new caffeine-containing energy products, from waffles to sunflower seeds, jelly beans to syrup, even bottled water, entering the marketplace. Years of scientific research have shown that moderate consumption by healthy adults of products containing naturally-occurring caffeine is not associated with adverse health effects. The changing caffeine landscape raises concerns about safety and whether any of these new products might be targeting populations not normally associated with caffeine consumption, namely children and adolescents, and whether caffeine poses a greater health risk to those populations than it does for healthy adults. This report delineates vulnerable populations who may be at risk from caffeine exposure; describes caffeine exposure and risk of cardiovascular and other health effects on vulnerable populations, including additive effects with other ingredients and effects related to pre-existing conditions; explores safe caffeine exposure levels for general and vulnerable populations; and identifies data gaps on caffeine stimulant effects.

Cardiovascular Physiology E-Book

Author : Achilles J. Pappano
Publisher : Elsevier Health Sciences
Page : 305 pages
File Size : 46,78 MB
Release : 2012-12-20
Category : Medical
ISBN : 0323088260

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Cardiovascular Physiology gives you a solid understanding of how the cardiovascular system functions in both health and disease. Ideal for your systems-based curriculum, this title in the Mosby Physiology Monograph Series explains how the latest concepts apply to real-life clinical situations. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Get clear, accurate, and up-to-the-minute coverage of the physiology of the cardiovascular system. Master the material easily with objectives at the start of each chapter; self-study questions, summaries, and key words and concepts. Grasp the latest concepts in vascular, molecular, and cellular biology as they apply to cardiovascular function, thanks to molecular commentaries in each chapter. Apply information to clinical situations with the aid of clinical commentaries and highlighted clinical vignettes throughout.