[PDF] Handbook Of Systems Toxicology 2 Volume Set eBook

Author : Daniel A. Casciano
Publisher : Wiley
Page : 1022 pages
File Size : 33,79 MB
Release : 2011-04-25
Category : Science
ISBN : 9780470684016

GET BOOK

In the first handbook to comprehensively cover the emerging area of systems toxicology, the Handbook of Systems Toxicology provides an authoritative compilation of up-to-date developments presented by internationally recognised investigators. Focusing on two rapidly developing cutting edge technologies – "omics" technology and nanotechnology with special emphasis on their applications – the scope and structure reflects the multidimensional character of these areas of toxicological research. Cutting edge molecular technologies such as microarray, proteomics, metabolomics, informatics, biomarkers, in vivo and in vitro models as well as the use of these new technologies in regulatory environments are addressed. An insight into the current trends and future directions of research in this rapidly developing field is also provided, offering an excellent source of authoritative and up-to-date information for investigators, toxicologists, risk assessors and regulators in academia, industry and government. New online resource available now! In 2011, the content from the Handbook of Systems Toxicology merged with the third edition of the six-volume General and Applied Toxicology. The result? General, Applied and Systems Toxicology - a new online resource combining traditional toxicology with the latest developments to present the ultimate reference in toxicology! For full details visit wileyonlinelibrary.com/ref/gast

Author : Gunnar F. Nordberg
Publisher : Academic Press
Page : 798 pages
File Size : 37,48 MB
Release : 2021-11-30
Category : Medical
ISBN : 0128232935

GET BOOK

Handbook on the Toxicology of Metals, Fifth Edition, Volume I: General Considerations is the first volume of a two-volume work that gives an overview and covers topics of general importance including reviews of various health effects of trace metals. The book emphasizes toxic effects in humans, along with discussions on the toxic effects of animals and biological systems in vitro when relevant. The book has been systematically updated with the latest studies and advances in technology and contains several new chapters. As a multidisciplinary resource that integrates both human and environmental toxicology, the book is a comprehensive and valuable reference for toxicologists, physicians, pharmacologists, and environmental scientists in the fields of environmental, occupational and public health. Contains peer-reviewed chapters that deal with the effects of metallic elements and their compounds on biological systems Includes information on sources, transport and the transformation of metals in the environment Covers the ecological effects of metals to provide a basis for better understanding of the potential for adverse effects on human health Provides critical information on the properties, use, biological monitoring, dose-response relationships, diagnosis, treatment and prevention of metallic elements and compounds

Author : Wanda M. Haschek
Publisher : San Diego : Academic Press
Page : 1012 pages
File Size : 49,33 MB
Release : 2002
Category : Pathology
ISBN :

GET BOOK

In volume I, the book covers toxicologic pathology in its basic aspects, including its definition, the basic biochemical and morphologic mechanisms underlying the discipline, the basic practice of toxicologic pathology (including special techniques) and issues essential to the understanding of toxicologic pathology such as risk assessment, experimental design, and statistical analysis. Next, the book moves to specific issues affecting the "practice" toxicologic pathology, including issues such as knowledge management, regulatory affairs and writing pathology reports. Finally, Volume I closes with several chapters that deal with specific classes of environmental toxicants such as endocrine disruptors and heavy metals. Volume II addresses the toxicologic pathology in a thoroughly standardized systems manner, addressing the basic structure and function of a particular organ system, its response to toxic injury, mechanisms of injury and methods of evaluation of such injury.-

Author : Ali S. Faqi
Publisher : Academic Press
Page : 904 pages
File Size : 40,85 MB
Release : 2012-11-02
Category : Business & Economics
ISBN : 0123878152

GET BOOK

A Comprehensive Guide to Toxicology in Preclinical Drug Development is designed for toxicologists who need a thorough understanding of the drug development process. This multi-contributed reference will provide a detailed picture of the complex and highly interrelated activities of preclinical toxicology in both small molecules and biologics --

Author : Swaran Jeet Singh Flora
Publisher : Academic Press
Page : 988 pages
File Size : 10,89 MB
Release : 2023-02-21
Category : Medical
ISBN : 0323984711

GET BOOK

Handbook of Arsenic Toxicology, Second Edition presents the latest findings on arsenic, including its chemistry, sources and effects on the environment and human health. The book discusses both acute and chronic effects, discussing many aspects of arsenic, from physical and chemical properties, exposure, epidemiology, organ toxicity, diagnosis, prevention and treatment. Fully updated and revised, this new edition includes new topics on risk assessment, molecular mechanisms of arsenic, advances in the integrated approach to testing, assessment and development, evaluation and application of high content predictive models, and new alternative methods (NAMS) in the context of Adverse Outcome Pathways (AOPs) to assess toxicology. This comprehensive resource allows readers to effectively assess the risks related to arsenic, providing them with all they need to know on arsenic exposure, toxicity and toxicity prevention. Brings together current findings on the effects of arsenic on the environment and human health Includes state-of-the-art techniques in arsenic toxicokinetics, speciation and molecular mechanisms Provides all the information needed for effective risk assessment, prevention and countermeasures

Author : Daniel A. Casciano
Publisher : Wiley
Page : 1022 pages
File Size : 39,88 MB
Release : 2011-04-25
Category : Science
ISBN : 9780470684016

GET BOOK

In the first handbook to comprehensively cover the emerging area of systems toxicology, the Handbook of Systems Toxicology provides an authoritative compilation of up-to-date developments presented by internationally recognised investigators. Focusing on two rapidly developing cutting edge technologies – "omics" technology and nanotechnology with special emphasis on their applications – the scope and structure reflects the multidimensional character of these areas of toxicological research. Cutting edge molecular technologies such as microarray, proteomics, metabolomics, informatics, biomarkers, in vivo and in vitro models as well as the use of these new technologies in regulatory environments are addressed. An insight into the current trends and future directions of research in this rapidly developing field is also provided, offering an excellent source of authoritative and up-to-date information for investigators, toxicologists, risk assessors and regulators in academia, industry and government. New online resource available now! In 2011, the content from the Handbook of Systems Toxicology merged with the third edition of the six-volume General and Applied Toxicology. The result? General, Applied and Systems Toxicology - a new online resource combining traditional toxicology with the latest developments to present the ultimate reference in toxicology! For full details visit wileyonlinelibrary.com/ref/gast

Author : Gunnar F. Nordberg
Publisher : Academic Press
Page : 1054 pages
File Size : 26,54 MB
Release : 2021-12-01
Category : Medical
ISBN : 0128231386

GET BOOK

Handbook on the Toxicology of Metals, Volume II: Specific Metals, Fifth Edition provides complete coverage of 38 individual metals and their compounds. This volume is the second volume of a two-volume work which emphasizes toxic effects in humans, along with discussions on the toxic effects of animals and biological systems in vitro when relevant. The book has been systematically updated with the latest studies and advances in technology. As a multidisciplinary resource that integrates both human and environmental toxicology, the book is a comprehensive and valuable reference for toxicologists, physicians, pharmacologists, and environmental scientists in the fields of environmental, occupational and public health. Contains peer-reviewed chapters that deal with the effects of metallic elements and their compounds on biological systems with a focus on human health effects Includes information on sources, transport, and the transformation of metals in the environment Provides critical information on the properties, use, biological monitoring, dose-response relationships, diagnosis, treatment, and prevention of 38 metallic elements and their compounds

Author : Michael J. Derelanko
Publisher : CRC Press
Page : 1448 pages
File Size : 44,23 MB
Release : 2001-08-29
Category : Medical
ISBN : 9780849303708

GET BOOK

LOCATE FREQUENTLY USED INFORMATION EASILY AND QUICKLY Working in the laboratory or office, you use a diverse assortment of basic information to design, conduct, and interpret toxicology studies and to perform risk assessments. The Second Edition of the best-selling Handbook of Toxicology gives you the information you need in a single reference source. NEW IN THIS EDITION: Expanded coverage of inhalation toxicology, neurotoxicology, and histopathology Additional regulatory chapters dealing with pesticides, medical devices, consumer products, and world-wide notification of new chemicals Areas of toxicology missing from the first edition such as ecotoxicology and in vitro toxicology A chapter providing extensive overview of the toxicology of metals Two chapters on basic male and female endocrinology and related toxicology Information on differences in physiological and biochemical parameters between children and adults References to Web site sources of valuable information Over 200 new tables and figures THE SINGLE SOURCE FOR THE INFORMATION YOU USE MOST FREQUENTLY Updated and expanded, this unique book includes practical reference information useful to toxicologists in the chemical and pharmaceutical industries, contract laboratories, regulatory agencies, and academia. To help you find information quickly and easily, data is arranged by toxicology subspecialty and each chapter begins with a detailed listing of information presented. Containing over 700 tables and figures, Handbook of Toxicology, Second Edition gives you a single source for the information you use most often.

Author : P.J. Bert Hakkinen
Publisher : Elsevier
Page : 953 pages
File Size : 23,29 MB
Release : 2000-01-10
Category : Medical
ISBN : 008053466X

GET BOOK

Information Resources in Toxicology, Third Edition is a sourcebook for anyone who needs to know where to find toxicology information. It provides an up-to-date selective guide to a large variety of sources--books, journals, organizations, audiovisuals, internet and electronic sources, and more. For the Third Edition, the editors have selected, organized, and updated the most relevant information available. New information on grants and other funding opportunities, physical hazards, patent literature, and technical reports have also been added.This comprehensive, time-saving tool is ideal for toxicologists, pharmacologists, drug companies, testing labs, libraries, poison control centers, physicians, legal and regulatory professionals, and chemists. Serves as an all-in-one resource for toxicology information New edition includes information on publishers, grants and other funding opportunities, physical hazards, patent literature, and technical reports Updated to include the latest internet and electronic sources, e-mail addresses, etc. Provides valuable data about the new fields that have emerged within toxicological research; namely, the biochemical, cellular, molecular, and genetic aspects