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Genome

Author : Matt Ridley
Publisher : Harper Collins
Page : 370 pages
File Size : 50,8 MB
Release : 2013-03-26
Category : Science
ISBN : 0062253468

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“Ridley leaps from chromosome to chromosome in a handy summation of our ever increasing understanding of the roles that genes play in disease, behavior, sexual differences, and even intelligence. . . . . He addresses not only the ethical quandaries faced by contemporary scientists but the reductionist danger in equating inheritability with inevitability.” — The New Yorker The genome's been mapped. But what does it mean? Matt Ridley’s Genome is the book that explains it all: what it is, how it works, and what it portends for the future Arguably the most significant scientific discovery of the new century, the mapping of the twenty-three pairs of chromosomes that make up the human genome raises almost as many questions as it answers. Questions that will profoundly impact the way we think about disease, about longevity, and about free will. Questions that will affect the rest of your life. Genome offers extraordinary insight into the ramifications of this incredible breakthrough. By picking one newly discovered gene from each pair of chromosomes and telling its story, Matt Ridley recounts the history of our species and its ancestors from the dawn of life to the brink of future medicine. From Huntington's disease to cancer, from the applications of gene therapy to the horrors of eugenics, Ridley probes the scientific, philosophical, and moral issues arising as a result of the mapping of the genome. It will help you understand what this scientific milestone means for you, for your children, and for humankind.

Nature Via Nurture

Author : Matt Ridley
Publisher : Harper Collins
Page : 340 pages
File Size : 15,5 MB
Release : 2003-04-29
Category : Psychology
ISBN : 0060006781

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Following his highly praised and bestselling book Genome: The Autobiography of a Species in 23 Chapters, Matt Ridley has written a brilliant and profound book about the roots of human behavior. Nature via Nurture explores the complex and endlessly intriguing question of what makes us who we are. In February 2001 it was announced that the human genome contains not 100,000 genes, as originally postulated, but only 30,000. This startling revision led some scientists to conclude that there are simply not enough human genes to account for all the different ways people behave: we must be made by nurture, not nature. Yet again biology was to be stretched on the Procrustean bed of the nature-nurture debate. Matt Ridley argues that the emerging truth is far more interesting than this myth. Nurture depends on genes, too, and genes need nurture. Genes not only predetermine the broad structure of the brain, they also absorb formative experiences, react to social cues, and even run memory. They are consequences as well as causes of the will. Published fifty years after the discovery of the double helix of DNA, Nature via Nurture chronicles a revolution in our understanding of genes. Ridley recounts the hundred years' war between the partisans of nature and nurture to explain how this paradoxical creature, the human being, can be simultaneously free-willed and motivated by instinct and culture. Nature via Nurture is an enthralling,up-to-the-minute account of how genes build brains to absorb experience.

Genome

Author : Matt Ridley
Publisher : Turtleback Books
Page : 344 pages
File Size : 22,10 MB
Release : 2000-09-30
Category : Science
ISBN : 9780606314152

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Looks at one newly described gene from each of the twenty-three human chromosomes and explains how each one contributes to our uniqueness as a species.

DNA

Author : James D. Watson
Publisher : Knopf
Page : 464 pages
File Size : 29,38 MB
Release : 2009-01-21
Category : Science
ISBN : 0307521486

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Fifty years ago, James D. Watson, then just twentyfour, helped launch the greatest ongoing scientific quest of our time. Now, with unique authority and sweeping vision, he gives us the first full account of the genetic revolution—from Mendel’s garden to the double helix to the sequencing of the human genome and beyond. Watson’s lively, panoramic narrative begins with the fanciful speculations of the ancients as to why “like begets like” before skipping ahead to 1866, when an Austrian monk named Gregor Mendel first deduced the basic laws of inheritance. But genetics as we recognize it today—with its capacity, both thrilling and sobering, to manipulate the very essence of living things—came into being only with the rise of molecular investigations culminating in the breakthrough discovery of the structure of DNA, for which Watson shared a Nobel prize in 1962. In the DNA molecule’s graceful curves was the key to a whole new science. Having shown that the secret of life is chemical, modern genetics has set mankind off on a journey unimaginable just a few decades ago. Watson provides the general reader with clear explanations of molecular processes and emerging technologies. He shows us how DNA continues to alter our understanding of human origins, and of our identities as groups and as individuals. And with the insight of one who has remained close to every advance in research since the double helix, he reveals how genetics has unleashed a wealth of possibilities to alter the human condition—from genetically modified foods to genetically modified babies—and transformed itself from a domain of pure research into one of big business as well. It is a sometimes topsy-turvy world full of great minds and great egos, driven by ambitions to improve the human condition as well as to improve investment portfolios, a world vividly captured in these pages. Facing a future of choices and social and ethical implications of which we dare not remain uninformed, we could have no better guide than James Watson, who leads us with the same bravura storytelling that made The Double Helix one of the most successful books on science ever published. Infused with a scientist’s awe at nature’s marvels and a humanist’s profound sympathies, DNA is destined to become the classic telling of the defining scientific saga of our age.

The Human Genome Project

Author : Thomas F. Lee
Publisher : Springer
Page : 322 pages
File Size : 38,56 MB
Release : 2013-12-11
Category : Medical
ISBN : 1489960228

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Describes the ten-year, multimillion dollar Human Genome Project and its process of gene mapping; includes concerns of critics of the project.

The Red Queen

Author : Matt Ridley
Publisher : Penguin UK
Page : 459 pages
File Size : 22,75 MB
Release : 1994-10-06
Category : Psychology
ISBN : 0141965452

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Sex is as fascinating to scientists as it is to the rest of us. A vast pool of knowledge, therefore, has been gleaned from research into the nature of sex, from the contentious problem of why the wasteful reproductive process exists at all, to how individuals choose their mates and what traits they find attractive. This fascinating book explores those findings, and their implications for the sexual behaviour of our own species. It uses the Red Queen from ‘Alice in Wonderland’ – who has to run at full speed to stay where she is – as a metaphor for a whole range of sexual behaviours. The book was shortlisted for the 1994 Rhone-Poulenc Prize for Science Books. ‘Animals and plants evolved sex to fend off parasitic infection. Now look where it has got us. Men want BMWs, power and money in order to pair-bond with women who are blonde, youthful and narrow-waisted ... a brilliant examination of the scientific debates on the hows and whys of sex and evolution’ Independent.

DNA Demystified

Author : Alan McHughen
Publisher : Oxford University Press, USA
Page : 393 pages
File Size : 24,93 MB
Release : 2020
Category : DNA.
ISBN : 0190092963

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"DNA Demystified satisfies the public appetite for and curiosity about DNA and genetics ... [The author], an accomplished academic and public science advocate, brings the reader up-to-speed on what we know, what we don't, and where genetic technologies are taking us. The book begins with the basic groundwork and a brief history of DNA and genetics. Chapters then cover newsworthy topics, including DNA fingerprinting, using DNA in forensic analyses, and identifying cold-case criminals. For readers intrigued by at-home DNA tests, the text includes fascinating explorations of genetic genealogy and family tree construction--crucial for people seeking their biological ancestry. Other chapters describe genetic engineering in medicine and pharmaceuticals, and the use of those same technologies in creating the far more controversial GMOs in food and agriculture. Throughout, the book raises provocative ethical and privacy issues arising from DNA and genetic technologies"--

The Epigenetics Revolution

Author : Nessa Carey
Publisher : Columbia University Press
Page : 353 pages
File Size : 43,15 MB
Release : 2012-03-06
Category : Science
ISBN : 0231530714

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Epigenetics can potentially revolutionize our understanding of the structure and behavior of biological life on Earth. It explains why mapping an organism's genetic code is not enough to determine how it develops or acts and shows how nurture combines with nature to engineer biological diversity. Surveying the twenty-year history of the field while also highlighting its latest findings and innovations, this volume provides a readily understandable introduction to the foundations of epigenetics. Nessa Carey, a leading epigenetics researcher, connects the field's arguments to such diverse phenomena as how ants and queen bees control their colonies; why tortoiseshell cats are always female; why some plants need cold weather before they can flower; and how our bodies age and develop disease. Reaching beyond biology, epigenetics now informs work on drug addiction, the long-term effects of famine, and the physical and psychological consequences of childhood trauma. Carey concludes with a discussion of the future directions for this research and its ability to improve human health and well-being.

Ancestors in Our Genome

Author : Eugene E. Harris (Professor)
Publisher : Oxford University Press, USA
Page : 249 pages
File Size : 24,31 MB
Release : 2015
Category : Science
ISBN : 0199978034

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Geneticist Eugene Harris presents us with the complete and up-to-date account of the evolution of the human genome.

The Genome Odyssey

Author : Dr. Euan Angus Ashley
Publisher : Celadon Books
Page : 221 pages
File Size : 31,17 MB
Release : 2021-02-23
Category : Science
ISBN : 1250234972

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In The Genome Odyssey, Dr. Euan Ashley, Stanford professor of medicine and genetics, brings the breakthroughs of precision medicine to vivid life through the real diagnostic journeys of his patients and the tireless efforts of his fellow doctors and scientists as they hunt to prevent, predict, and beat disease. Since the Human Genome Project was completed in 2003, the price of genome sequencing has dropped at a staggering rate. It’s as if the price of a Ferrari went from $350,000 to a mere forty cents. Through breakthroughs made by Dr. Ashley’s team at Stanford and other dedicated groups around the world, analyzing the human genome has decreased from a heroic multibillion dollar effort to a single clinical test costing less than $1,000. For the first time we have within our grasp the ability to predict our genetic future, to diagnose and prevent disease before it begins, and to decode what it really means to be human. In The Genome Odyssey, Dr. Ashley details the medicine behind genome sequencing with clarity and accessibility. More than that, with passion for his subject and compassion for his patients, he introduces readers to the dynamic group of researchers and doctor detectives who hunt for answers, and to the pioneering patients who open up their lives to the medical community during their search for diagnoses and cures. He describes how he led the team that was the first to analyze and interpret a complete human genome, how they broke genome speed records to diagnose and treat a newborn baby girl whose heart stopped five times on the first day of her life, and how they found a boy with tumors growing inside his heart and traced the cause to a missing piece of his genome. These patients inspire Dr. Ashley and his team as they work to expand the boundaries of our medical capabilities and to envision a future where genome sequencing is available for all, where medicine can be tailored to treat specific diseases and to decode pathogens like viruses at the genomic level, and where our medical system as we know it has been completely revolutionized.