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Fundamental Statistical Methods for Analysis of Alzheimer's and Other Neurodegenerative Diseases

Author : Katherine E. Irimata
Publisher : Johns Hopkins University Press
Page : 481 pages
File Size : 10,12 MB
Release : 2020-05-05
Category : Medical
ISBN : 142143671X

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Allowing more people to aid in analyzing data—while promoting constructive dialogues with statisticians—this book will hopefully play an important part in unlocking the secrets of these confounding diseases.

Alzheimer's Disease

Author : Nigel M. Hooper
Publisher : Springer Science & Business Media
Page : 411 pages
File Size : 30,85 MB
Release : 2008-02-02
Category : Medical
ISBN : 1592591957

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Alzheimer's disease is the most common cause of senile dementia. Since the discovery in 1984 of the amyloid ?-peptide (A?) as the core protein of the senile plaques present in the brains of Alzheimer's disease sufferers, an immense amount of research has gone into mapping out the molecular basis of this debilitating disease. The aim of Alzheimer's Disease: Methods and Protocols is to bring together the main biochemical, cell biological, and molecular biological techniques and approaches that are being used to investigate the molecular basis of Alzheimer's disease. This volume begins with chapters of an introductory/ review nature. Chapter 1 provides a historical introduction to Alzheimer's d- ease with particular emphasis on the central role played by A? and its re- tion to tau. Chapter 2 examines the genetics underlying this neurodegenerative disease, covering the amyloid precursor protein, apolipoprotein E, and the presenilins. Chapter 3 presents an overview of currently available therapeutic agents and prospects for drugs of the future.

Reducing the Impact of Dementia in America

Author : National Academies of Sciences Engineering and Medicine
Publisher :
Page : pages
File Size : 28,41 MB
Release : 2022-04-26
Category :
ISBN : 9780309495035

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As the largest generation in U.S. history - the population born in the two decades immediately following World War II - enters the age of risk for cognitive impairment, growing numbers of people will experience dementia (including Alzheimer's disease and related dementias). By one estimate, nearly 14 million people in the United States will be living with dementia by 2060. Like other hardships, the experience of living with dementia can bring unexpected moments of intimacy, growth, and compassion, but these diseases also affect people's capacity to work and carry out other activities and alter their relationships with loved ones, friends, and coworkers. Those who live with and care for individuals experiencing these diseases face challenges that include physical and emotional stress, difficult changes and losses in their relationships with life partners, loss of income, and interrupted connections to other activities and friends. From a societal perspective, these diseases place substantial demands on communities and on the institutions and government entities that support people living with dementia and their families, including the health care system, the providers of direct care, and others. Nevertheless, research in the social and behavioral sciences points to possibilities for preventing or slowing the development of dementia and for substantially reducing its social and economic impacts. At the request of the National Institute on Aging of the U.S. Department of Health and Human Services, Reducing the Impact of Dementia in America assesses the contributions of research in the social and behavioral sciences and identifies a research agenda for the coming decade. This report offers a blueprint for the next decade of behavioral and social science research to reduce the negative impact of dementia for America's diverse population. Reducing the Impact of Dementia in America calls for research that addresses the causes and solutions for disparities in both developing dementia and receiving adequate treatment and support. It calls for research that sets goals meaningful not just for scientists but for people living with dementia and those who support them as well. By 2030, an estimated 8.5 million Americans will have Alzheimer's disease and many more will have other forms of dementia. Through identifying priorities social and behavioral science research and recommending ways in which they can be pursued in a coordinated fashion, Reducing the Impact of Dementia in America will help produce research that improves the lives of all those affected by dementia.

Imaging in Neurodegenerative Disorders

Author : Luca Saba
Publisher : Oxford University Press, USA
Page : 585 pages
File Size : 39,43 MB
Release : 2015
Category : Medical
ISBN : 0199671613

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This text summarizes the latest developments in imaging techniques and other new diagnostic methods as applied to the neurodegenerative disorders.

Alzheimer's In America

Author : Maria Shriver
Publisher : Free Press
Page : 0 pages
File Size : 30,40 MB
Release : 2011-04-12
Category : Health & Fitness
ISBN : 9781451639872

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The Shriver Report: A Woman’s Nation Takes on Alzheimer’s will be the first comprehensive multi-disciplinary look at these questions at this transformational moment. The Report will digest the current trends in thinking about Alzheimer’s, examine cutting-edge medical research, look at societal impacts, and include a groundbreaking and comprehensive national poll. It will feature original photography and personal essays by men and women – some from the public arena with names you know, some from everyday America – sharing their personal struggles with the disease as patients, caregivers and family members.

Alzheimer’s and Parkinson’s Diseases

Author : Israel Hanin
Publisher : Springer Science & Business Media
Page : 690 pages
File Size : 28,5 MB
Release : 2013-06-29
Category : Medical
ISBN : 1475791453

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This book represents the third in a series of International Conferences related to Alzheimer's (AD) and Parkinson's (PD) diseases. The first one took place in Eilat, Israel, in 1985; and the second one in Kyoto, Japan, in 1989. This book contains the full text of oral and poster presentations from the Third International Conference on Alzheimer's and Parkinson's Diseases: Recent Developments, held in Chicago, Illinois, U.S.A. on November 1-6, 1993. The Chicago Conference was attended by 270 participants. The Scientific Program was divided into nine oral sessions, a keynote presentation, and a poster session. The conference culminated in a Round Table Discussion involving all of the participants in the conference. The four and one-half day meeting served as an excellent medium for surveying the current status of clinical and preclinical developments in AD and PD. There were 59 oral presentations and 93 posters. This book incorporates a majority of both.

The 36-Hour Day

Author : Nancy L. Mace
Publisher : JHU Press
Page : 361 pages
File Size : 12,89 MB
Release : 2021-08-10
Category : Family & Relationships
ISBN : 1421441705

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The 36-Hour Day is the definitive dementia care guide.

Future Directions for the Demography of Aging

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
Page : 409 pages
File Size : 34,79 MB
Release : 2018-07-21
Category : Social Science
ISBN : 0309474108

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Almost 25 years have passed since the Demography of Aging (1994) was published by the National Research Council. Future Directions for the Demography of Aging is, in many ways, the successor to that original volume. The Division of Behavioral and Social Research at the National Institute on Aging (NIA) asked the National Academies of Sciences, Engineering, and Medicine to produce an authoritative guide to new directions in demography of aging. The papers published in this report were originally presented and discussed at a public workshop held in Washington, D.C., August 17-18, 2017. The workshop discussion made evident that major new advances had been made in the last two decades, but also that new trends and research directions have emerged that call for innovative conceptual, design, and measurement approaches. The report reviews these recent trends and also discusses future directions for research on a range of topics that are central to current research in the demography of aging. Looking back over the past two decades of demography of aging research shows remarkable advances in our understanding of the health and well-being of the older population. Equally exciting is that this report sets the stage for the next two decades of innovative researchâ€"a period of rapid growth in the older American population.

Basic Neurochemistry

Author : R. Wayne Albers
Publisher : Elsevier
Page : 1020 pages
File Size : 42,52 MB
Release : 2005-11-11
Category : Science
ISBN : 0080472079

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Basic Neurochemistry: Molecular, Cellular and Medical Aspects, a comprehensive text on neurochemistry, is now updated and revised in its Seventh Edition. This well-established text has been recognized worldwide as a resource for postgraduate trainees and teachers in neurology, psychiatry, and basic neuroscience, as well as for graduate and postgraduate students and instructors in the neurosciences. It is an excellent source of information on basic biochemical processes in brain function and disease for qualifying examinations and continuing medical education. Completely updated with 60% new authors and material, and entirely new chapters Over 400 fully revised figures in splendid color

Dementia with Lewy Bodies

Author : John O'Brien
Publisher : CRC Press
Page : 286 pages
File Size : 35,84 MB
Release : 2005-11-29
Category : Medical
ISBN : 0203313909

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Filling a noticeable gap in the market for a new text solely focused on Dementia with Lewy Bodies, this book discusses cutting-edge topics covering the condition from diagnosis to management, as well as what is known about the neurobiological changes involved. With huge progress having been made over the last decade in terms of the disorder