[PDF] Fundamental Concepts In Biophysics eBook

Author : Thomas Jue
Publisher : Springer Science & Business Media
Page : 262 pages
File Size : 20,81 MB
Release : 2009-04-20
Category : Science
ISBN : 1597453978

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In the first volume, Fundamental Concepts in Biophysics, the authors lay down a foundation for biophysics study. Rajiv Singh opens the book by pointing to the central importance of “Mathematical Methods in Biophysics”. William Fink follows with a discussion on “Quantum Mechanics Basic to Biophysical Methods”. Together, these two chapters establish some of the principles of mathematical physics underlying many biophysics techniques. Because computer modeling forms an intricate part of biophysics research, Subhadip Raychaudhuri and colleagues introduce the use of computer modeling in “Computational Modeling of Receptor–Ligand Binding and Cellular Signaling Processes”. Yin Yeh and coworkers bring to the reader’s attention the physical basis underlying the common use of fluorescence spectroscopy in biomedical research in their chapter “Fluorescence Spectroscopy”. Electrophysiologists have also applied biophysics techniques in the study of membrane proteins, and Tsung-Yu Chen et al. explore stochastic processes of ion transport in their “Electrophysiological Measurements of Membrane Proteins”. Michael Saxton takes up a key biophysics question about particle distribution and behavior in systems with spatial or temporal inhomogeneity in his chapter “Single–Particle Tracking”. Finally, in “NMR Measurement of Biomolecule Diffusion”, Thomas Jue explains how magnetic resonance techniques can map biomolecule diffusion in the cell to a theory of respiratory control. This book thus launches the Handbook of Modern Biophysics series and sets up for the reader some of the fundamental concepts underpinning the biophysics issues to be presented in future volumes.

Author : Andrey B. Rubin
Publisher : John Wiley & Sons
Page : 224 pages
File Size : 38,17 MB
Release : 2014-09-11
Category : Science
ISBN : 1118842758

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Biophysics is a science that comprises theoretical plotting and models based on contemporary physicochemical conceptions. They mirror physical specificity of the molecular organization and elementary processes in living organisms, which in their turn form the molecular basis of biological phenomena. Presentation of a complete course in biophysics requires vast biological material as well as additional involvement of state-of-the-art concepts in physics, chemistry and mathematics. This is essential for the students to "perceive" the specific nature and peculiarity of molecular biological processes and see how this specificity is displayed in biological systems. This is the essence of the up-to-date biophysical approach to the analysis of biological processes. Fundamentals of Biophysics offers a complete, thorough coverage of the material in a straightforward and no-nonsense format, offering a new and unique approach to the material that presents the appropriate topics without extraneous and unneeded filler material.

Author : Helmut Schiessel
Publisher : CRC Press
Page : 420 pages
File Size : 48,14 MB
Release : 2013-12-20
Category : Science
ISBN : 9814241652

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Biophysics is a new way of looking at living matter. It uses quantitative experimental and theoretical methods to open a new window for studying and understanding life processes. This textbook gives compact introductions to the basics of the field, including molecular cell biology and statistical physics. It then presents in-depth discussions of more advanced biophysics subjects, progressing to state-of-the-art experiments and their theoretical interpretations. The book is unique by offering a general introduction to biophysics, yet at the same time restricting itself to processes that occur inside the cell nucleus and that involve biopolymers (DNA, RNA, and proteins). This allows for an accessible read for beginners and a springboard for specialists who wish to continue their study in more detail.

Author : William Bialek
Publisher : Princeton University Press
Page : 653 pages
File Size : 46,32 MB
Release : 2012-12-17
Category : Science
ISBN : 1400845572

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A physicist's guide to the phenomena of life Interactions between the fields of physics and biology reach back over a century, and some of the most significant developments in biology—from the discovery of DNA's structure to imaging of the human brain—have involved collaboration across this disciplinary boundary. For a new generation of physicists, the phenomena of life pose exciting challenges to physics itself, and biophysics has emerged as an important subfield of this discipline. Here, William Bialek provides the first graduate-level introduction to biophysics aimed at physics students. Bialek begins by exploring how photon counting in vision offers important lessons about the opportunities for quantitative, physics-style experiments on diverse biological phenomena. He draws from these lessons three general physical principles—the importance of noise, the need to understand the extraordinary performance of living systems without appealing to finely tuned parameters, and the critical role of the representation and flow of information in the business of life. Bialek then applies these principles to a broad range of phenomena, including the control of gene expression, perception and memory, protein folding, the mechanics of the inner ear, the dynamics of biochemical reactions, and pattern formation in developing embryos. Featuring numerous problems and exercises throughout, Biophysics emphasizes the unifying power of abstract physical principles to motivate new and novel experiments on biological systems. Covers a range of biological phenomena from the physicist's perspective Features 200 problems Draws on statistical mechanics, quantum mechanics, and related mathematical concepts Includes an annotated bibliography and detailed appendixes

Author : Thomas M. Nordlund
Publisher : CRC Press
Page : 578 pages
File Size : 34,5 MB
Release : 2011-03-04
Category : Medical
ISBN : 1439891133

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Quantitative Understanding of Biosystems: An Introduction to Biophysics focuses on the behavior and properties of microscopic structures that underlie living systems. It clearly describes the biological physics of macromolecules, subcellular structures, and whole cells, including interactions with light.Providing broad coverage of physics, chemistr

Author : Jay L. Nadeau
Publisher : CRC Press
Page : 658 pages
File Size : 37,99 MB
Release : 2016-04-19
Category : Science
ISBN : 1439897409

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Increasing numbers of physicists, chemists, and mathematicians are moving into biology, reading literature across disciplines, and mastering novel biochemical concepts. To succeed in this transition, researchers must understand on a practical level what is experimentally feasible. The number of experimental techniques in biology is vast and often s

Author : Meyer B. Jackson
Publisher : Cambridge University Press
Page : 536 pages
File Size : 46,44 MB
Release : 2006-01-12
Category : Science
ISBN : 9780521624411

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Molecular and Cellular Biophysics provides advanced undergraduate and graduate students with a foundation in the basic concepts of biophysics. Students who have taken physical chemistry and calculus courses will find this book an accessible and valuable aid in learning how these concepts can be used in biological research. The text provides a rigorous treatment of the fundamental theories in biophysics and illustrates their application with examples. Conformational transitions of proteins are studied first using thermodynamics, and subsequently with kinetics. Allosteric theory is developed as the synthesis of conformational transitions and association reactions. Basic ideas of thermodynamics and kinetics are applied to topics such as protein folding, enzyme catalysis and ion channel permeation. These concepts are then used as the building blocks in a treatment of membrane excitability. Through these examples, students will gain an understanding of the general importance and broad applicability of biophysical principles to biological problems.

Author : Rodney Cotterill
Publisher : John Wiley & Sons
Page : 408 pages
File Size : 39,95 MB
Release : 2003-07-07
Category : Science
ISBN : 0470854561

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Biophysics is an evolving, multidisciplinary subject which applies physics to biological systems and promotes an understanding of their physical properties and behaviour. Biophysics: An Introduction, is a concise balanced introduction to this subject. Written in an accessible and readable style, the book takes a fresh, modern approach with the author successfully combining key concepts and theory with relevant applications and examples drawn from the field as a whole. Beginning with a brief introduction to the origins of biophysics, the book takes the reader through successive levels of complexity, from atoms to molecules, structures, systems and ultimately to the behaviour of organisms. The book also includes extensive coverage of biopolymers, biomembranes, biological energy, and nervous systems. The text not only explores basic ideas, but also discusses recent developments, such as protein folding, DNA/RNA conformations, molecular motors, optical tweezers and the biological origins of consciousness and intelligence. Biophysics: An Introduction * Is a carefully structured introduction to biological and medical physics * Provides exercises at the end of each chapter to encourage student understanding Assuming little biological or medical knowledge, this book is invaluable to undergraduate students in physics, biophysics and medical physics. The book is also useful for graduate students and researchers looking for a broad introduction to the subject.

Author : Betty Karasek
Publisher :
Page : 238 pages
File Size : 31,45 MB
Release : 2018-02-21
Category : Science
ISBN : 9781632385758

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Biophysics studies the methods and approaches of physics in relation to biological systems. Scientists and researchers related to the field of biophysics study the connections between DNA, RNA and protein biosynthesis. Some of the fields that converge with the field of biophysics are biology, biochemistry, computer science, computational chemistry, mathematics, etc. This book is a compilation of chapters that discuss the most vital concepts and emerging trends in the field of biophysics. This book, with its detailed analyses and data, will prove immensely beneficial to professionals and students involved in this area at various levels.