[PDF] Fragment eBook

Author : Warren Fahy
Publisher : Delacorte Press
Page : 386 pages
File Size : 48,26 MB
Release : 2009-06-16
Category : Fiction
ISBN : 0440338573

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Aboard a long-range research vessel, in the vast reaches of the South Pacific, the cast and crew of the reality show Sealife believe they have found a ratings bonanza. For a director dying for drama, a distress call from Henders Island—a mere blip on any radar—might be just the ticket. Until the first scientist sets foot on Henders—and the ultimate test of survival begins. For when they reach the island’s shores, the scientists are utterly unprepared for what they find—creatures unlike any ever recorded in natural history. This is not a lost world frozen in time; this is Earth as it might have looked after evolving on a separate path for half a billion years—a fragment of a lost continent, with an ecosystem that could topple ours like a house of cards.

Author :
Publisher : Rizzoli Publications
Page : 234 pages
File Size : 43,70 MB
Release : 2014-07-15
Category : Design
ISBN : 0847842398

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The first monograph on the "godfather of streetwear," this book pays homage to Hiroshi Fujiwara's influence on contemporary fashion, music, and design. The most comprehensive book devoted to the extensive work of Hiroshi Fujiwara-a pioneer in streetwear, music, and art, and the ultimate arbiter of cool. Known internationally as one of the founding fathers of Tokyo's Harajuku scene, Fujiwara exerts a disproportionate influence over contemporary design culture. Having collaborated with the likes of Malcolm McLaren and Vivienne Westwood as a teenager in the early 1980s, he merged a seminal interest in punk with hip-hop and skate culture to become one of Japan's principal tastemakers. A musician and producer, Fujiwara is also one of the most prolific sneaker designers, and his kicks are some of the most sought-after collectibles. In addition to his very visible and long-standing collaborations with Nike, he has authored a number of fashion lines and is at the head of the Tokyo-based Fragment Design. Chronicling his reign as the arbiter of hip for more than thirty years, this book presents the breadth of his career, including sections on his highly sought-after artwork and graphics, sneakers, product design, and curated personal effects. With contributions by Sarah Lerfel and Ino Hidefumi, this graphically inspired book provides a unique glimpse into one of the most influential tastemakers of our time and is the perfect follow-up to Rizzoli's Pharrell: Places and Spaces I've Been.

Author : Warren Fahy
Publisher : Macmillan
Page : 321 pages
File Size : 34,19 MB
Release : 2013-03-19
Category : Fiction
ISBN : 0765333295

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A ruthless Russian tycoon lures biologists Nell and Geoffrey to his underground metropolis, where they are confronted by a vicious menagerie of biological horrors that are rising up to consume the world.

Author : William Tronzo
Publisher : Getty Publications
Page : 234 pages
File Size : 45,87 MB
Release : 2009
Category : Art
ISBN : 0892369264

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The universe may well have begun with an immense act of fragmentation, "the big bang," that sent particles flying in all directions to perform spectacular acts of creation and destruction. The fragment, volatile and unpredictable, is not simply the static part of a once-whole thing but itself something in motion. Drawing upon art history, archaeology, literature, numismatics, philosophy, and film, this book explores the significance of the fragment and addresses the powerful drives that have impelled it into the cultural mainstream. Book jacket.

Author : Jeffry W. Johnston
Publisher : Simon and Schuster
Page : 212 pages
File Size : 42,19 MB
Release : 2007-01-09
Category : Juvenile Fiction
ISBN : 1416924868

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Chase wishes he could remember the events of his accident, but when the memories begin to come back in his dreams, Chase must face the reality of his past and finally deal with the part he played in the tragic event.

Author : Binjamin Wilkomirski
Publisher : Schocken
Page : 168 pages
File Size : 16,9 MB
Release : 1996
Category : Biography & Autobiography
ISBN :

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Memoir of a small boy who was separated from his family at the age of three or four-years-old after his father was killed during a round-up of Jews in Latvia, and was sent to the Majdanek death camp where he was discovered by Allied soldiers in 1945.

Author : Wolfgang Jahnke
Publisher : John Wiley & Sons
Page : 391 pages
File Size : 16,39 MB
Release : 2006-12-13
Category : Science
ISBN : 3527608605

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This first systematic summary of the impact of fragment-based approaches on the drug development process provides essential information that was previously unavailable. Adopting a practice-oriented approach, this represents a book by professionals for professionals, tailor-made for drug developers in the pharma and biotech sector who need to keep up-to-date on the latest technologies and strategies in pharmaceutical ligand design. The book is clearly divided into three sections on ligand design, spectroscopic techniques, and screening and drug discovery, backed by numerous case studies.

Author : Toni Jordan
Publisher : Text Publishing
Page : 336 pages
File Size : 47,69 MB
Release : 2018-10-29
Category : Fiction
ISBN : 192577404X

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From the award-winning, bestselling author of Addition and Nine Days, a superbly crafted and captivating literary mystery about a lost book and a secret love.

Author : Megan Miranda
Publisher : Crown Books For Young Readers
Page : 386 pages
File Size : 40,4 MB
Release : 2017
Category : Juvenile Fiction
ISBN : 0399556729

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Even though she thinks Caleb's mom blames her for his accidental death two months ago, Jessa agrees to pack up her ex-boyfriend's bedroom, but every item she touches makes Jessa question what she knows about his death, his family, and their year-long relationship.

Author : Edward R. Zartler
Publisher : John Wiley & Sons
Page : 296 pages
File Size : 21,85 MB
Release : 2008-11-20
Category : Science
ISBN : 0470721561

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Fragment-based drug discovery (FBDD) is a new paradigm in drug discovery that utilizes very small molecules - fragments of larger molecules. It is a faster, cheaper, smarter way to do drug discovery, as shown by the number of pharmaceutical companies that have embraced this approach and the biotechnology companies who use fragments as their sole source of drug discovery. Fragment-Based Drug Discovery: A Practical Approach is a guide to the techniques and practice of using fragments in drug screening. The emphasis is on practical guidance, with procedures, case studies, practical tips, and contributions from industry. Topics covered include: an introduction to fragment based drug discovery, why using fragments is a more efficient process than predominant models, and what it means to have a successful FBDD effort. setting up an FBDD project library building and production NMR in fragment screening and follow up application of protein-ligand NOE matching to the rapid evaluation of fragment binding poses target immobilized NMR screening: validation and extension to membrane proteins in situ fragment-based medicinal chemistry: screening by mass spectrometry computational approaches to fragment and substructure discovery and evaluation virtual fragment scanning: current trends, applications and web based tools fragment-based lead discovery using covalent capture methods case study from industry: the identification of high affinity beta-secretase inhibitors using fragment-based lead generation With contributions from industry experts who have successfully set up an industrial fragment-based research program, Fragment-Based Drug Discovery: A Practical Approach offers essential advice to anyone embarking on drug discovery using fragments and those looking for a new approach to screening for drugs.