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Fetus and Neonate: Physiology and Clinical Applications: Volume 1, The Circulation

Author : Mark A. Hanson
Publisher : Cambridge University Press
Page : 458 pages
File Size : 42,68 MB
Release : 1993-04-15
Category : Medical
ISBN : 9780521423274

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The Fetus and Neonate is a series of practical, focused texts which concentrate on that critical period of human development, from late fetal to neonatal life. Each volume in the series examines a particular body system, looking at the physiological mechanisms which underlie the transition from intrauterine to extrauterine life, and the pathophysiological processes which may occur in this period. Each volume will consider the application of new basic scientific knowledge to the clinical situation. This series will be a valuable source of information to practitioners and postgraduate trainees in obstetrics, neonatology, paediatrics and reproductive medicine, as well as to basic scientists in these fields.

Vascular Biology of the Placenta

Author : Yuping Wang
Publisher : Biota Publishing
Page : 126 pages
File Size : 39,82 MB
Release : 2017-06-23
Category : Medical
ISBN : 1615047514

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The placenta is an organ that connects the developing fetus to the uterine wall, thereby allowing nutrient uptake, waste elimination, and gas exchange via the mother's blood supply. Proper vascular development in the placenta is fundamental to ensuring a healthy fetus and successful pregnancy. This book provides an up-to-date summary and synthesis of knowledge regarding placental vascular biology and discusses the relevance of this vascular bed to the functions of the human placenta.

Hepatic Circulation

Author : W. Wayne Lautt
Publisher : Morgan & Claypool Publishers
Page : 174 pages
File Size : 11,81 MB
Release : 2009-11-17
Category : Science
ISBN : 1615040099

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The Hepatic circulation is unique among vascular beds. The most obvious unique features include the dual vascular supply; the mechanism of intrinsic regulation of the hepatic artery (the hepatic arterial buffer response); the fact that portal blood flow, supplying two thirds of liver blood flow, is not controlled directly by the liver; the fact that 20% of the cardiac output rushes through the most vascularized organ in the body, driven by a pressure gradient of only a few millimeters of mercury; the extremely distensible capacitance and venous resistance sites; the unidirectional acinar blood flow that regulates parenchymal cell metabolic specialization; and the high concentration of macrophagic (Kupffer) cells filtering the blood. The liver is the only organ reported to have regional blood flow monitored by the autonomic nervous system. This mechanism, when dysfunctional, accounts for the hepatorenal syndrome and offers a mechanistic therapeutic target to treat this syndrome. The trigger for liver regeneration is dependent on hepatic hemodynamics so that chronic liver blood flow regulates liver cell mass. In severe liver disease, the whole body circulation is reorganized, by forming portacaval shunts, to accommodate the increased intrahepatic venous resistance. These shunts protect the venous drainage of the splanchnic organs but lead to loss of major regulatory roles of the liver. The development of knowledge of the hepatic vasculature is presented from a historical perspective with modern concepts summarized based on the perspective of the author's four decades of devotion to this most marvelous of organs. Table of Contents: Acknowledgements / Historical Perspectives / Overview / Fluid Exchange / Capacitance / Resistance in the Hepatic Artery / Resistance in the Venous System / Fetal and Neonatal Hepatic Circulation / In Vivo Pharmacodynamic Approaches / Nitric Oxide / Adenosine / Hepatic Nerves / Hepatic Circulation and Toxicology / Hepatorenal Syndrome / Integrative Hepatic Response to Hemorrhage / Blood Flow Regulation of Hepatocyte Proliferation / Multiple Mechanisms Maintaining a Constant Hepatic Blood Flow to Liver Mass Ratio / Pathopharmacology and Repurposing Drugs as a Research Strategy / References

Physics, Pharmacology and Physiology for Anaesthetists

Author : Matthew E. Cross
Publisher : Cambridge University Press
Page : 439 pages
File Size : 13,51 MB
Release : 2014-03-06
Category : Medical
ISBN : 1107615887

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A quick reference to basic science for anaesthetists, containing all the key information needed for FRCA exams.

The Fetus and Neonate

Author : N. S. Assali
Publisher : Academic Press
Page : 426 pages
File Size : 26,64 MB
Release : 2013-10-22
Category : Medical
ISBN : 1483282325

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Biology of Gestation Volume II provides an account of the various mechanisms that take place during the adjustment of the fetus to intrauterine life and the changes that happen at birth. The book covers topics such as the growth and composition of the newborn and the fetus, fetal and neonatal circulation, and maternal and fetal blood constituents. Also covered are topics such as the lung and kidneys, and the development of the nervous system and immunologic function of neonates and the fetus. The text is recommended for biologists and doctors, especially gynecologists and pediatricians, who would like to know more about the anatomy and biological processes of fetuses and neonates.

Placental-Fetal Growth Restriction

Author : Christoph Lees
Publisher : Cambridge University Press
Page : 300 pages
File Size : 34,28 MB
Release : 2018-03-31
Category : Medical
ISBN : 1108548180

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Master the effective evaluation, analysis and management of placental-fetal growth restriction (PFGR), reducing the risk of perinatal mortality and morbidity in patients worldwide. Extensively researched by international experts, this manual provides practitioners with a detailed, hands-on approach to the practical 'pearls' for direct patient management. This authoritative volume advises on matters such as the correct evaluation and management of high-risk patients in danger of PFGR through to delivery. Extensive and wide-ranging, this book is an invaluable companion to the developing research interest and clinical applications in PFGR, including developmental outcomes in early childhood. Featuring a critical evaluation of a variety of abnormal conditions, such as fetal hypoxia, which are clearly displayed through extensive illustrations. This essential toolkit ensures that practitioners of all levels can effectively limit the risk of mortality and morbidity, and reach the correct diagnosis, first-time.

Case Studies in Pediatric Anesthesia

Author : Adam C. Adler
Publisher : Cambridge University Press
Page : 363 pages
File Size : 46,79 MB
Release : 2019-12-05
Category : Medical
ISBN : 110846551X

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Covers the most important and relevant topics on the anesthetic care of children, using a question-and-answer format.

Neonatal Hematology

Author : Pedro A. de Alarcón
Publisher : Cambridge University Press
Page : 501 pages
File Size : 23,21 MB
Release : 2021-02-18
Category : Medical
ISBN : 1108488986

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An essential guide to the pathogenesis, diagnosis and management of hematologic problems in the neonate, covering erythrocyte disorders, leukocyte disorders, immunologic disorders and hemostatic disorders. Guidance is practical, including blood test interpretation, advice on transfusions and reference ranges for hematological values.

Core Topics in Congenital Cardiac Surgery

Author : David J. Barron
Publisher : Cambridge University Press
Page : 148 pages
File Size : 11,45 MB
Release : 2018-05-17
Category : Medical
ISBN : 1108632130

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Featuring a combination of easily digestible sections, clinical images, and a text layout that assists rapid fact acquisition, this book highlights the core topics in congenital cardiac surgery. The text covers all the commonly encountered anomalies, with simple explanations of the underlying anatomy and management options. Readers are provided with strong support from the outset; including guidance on diagnosis, operative technique, and post-operative management. Aimed at trainees preparing for professional examination and newly appointed consultants, this invaluable handbook is a go-to resource for the busy practitioner. It will also be an ideal reference for cardiologists, intensivists, perfusionists, and cardiac nurses, requiring a concise and accessible summary of the surgical aspects of diagnosis and treatment. The book includes sections on transplantation, ECMO, hybrid procedures and adult congenital heart disease.