[PDF] Experimental And Clinical Neuropathology eBook

Author : James S. Nelson
Publisher : Oxford University Press
Page : 609 pages
File Size : 28,4 MB
Release : 2003-03-20
Category : Medical
ISBN : 0198029071

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From reviews of the First Edition: "Being a concise introduction to the principles of neruopathology is a goal this book accomplishes admirably." Annals of Neurology; "unquestionably valuable as a reference text" Arch Path Lab Med; "a fine treatise which truly reflects the current knowledge of the discipline with a strong emphasis on morphologic aspects" Brain Pathology; "an excellent current reference work on neuropathology for practitioners in the various clinical and basic neurosciences" Journal of Neuropathology and Experimental Neurology.

Author : Draoui, Ahmed
Publisher : IGI Global
Page : 475 pages
File Size : 40,74 MB
Release : 2023-08-04
Category : Medical
ISBN : 1668451573

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Parkinson’s disease is the second most common neurodegenerative disorder in the world after Alzheimer’s disease. Thanks to the pioneering works of Arvid Carlson in the 20th century identifying dopamine as the main neurochemical agent involved in Parkinson’s disease’s onset and progress, our understanding of the neuropathology has increased. The elaboration of L-Dopa as the first pharmacological treatment approach has brought new hope for curing or at least slowing the neurodegenerative progress and the decline of motor and cognitive functions in Parkinson’s disease patients. To date, imaging techniques along with genetic and biochemical tools have allowed scientists and clinicians to predict and diagnose the disease several years prior to the motor disorder’s appearance. Experimental and Clinical Evidence of the Neuropathology of Parkinson’s Disease sheds light on the history of Parkinson’s disease as well as the recent literature on the epidemiological data worldwide including the prevalence of the disease, the morbimortality rates, and the sex dimorphism and aging components. It addresses the current neuropathological evidence of Parkinson’s disease, including the latest discoveries in terms of neuropathology and treatments available or under clinical trials with the efficacy and limitations of each. Covering topics such as epidemiology, stem cells, and neuropathology, this premier reference source is an excellent resource for clinicians, physicians, epidemiologists, neuroscientists, microbiologists, biochemists, pharmacologists, toxicologists, medical professionals, nurses, medical students and educators, librarians, researchers, and academicians.

Author : Catherine Haberland, MD
Publisher : Demos Medical Publishing
Page : 336 pages
File Size : 27,80 MB
Release : 2006-12-27
Category : Medical
ISBN : 1934559520

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Divided into fourteen chapters, this text and full-color atlas is a complete overview of the pathologic and clinical aspects of neurologic diseases. Clinical Neuropathology is written for practicing neurologists and pathologists, as well as residents and fellows preparing for the neurology and pathology boards. It provides information on the structural alterations of nervous system diseases along with their clinical manifestations. The first two chapters cover the process and goals of the neuropathologic exam and histological reactions particular to the nervous system. Subsequent chapters review major disease categories, with each section containing an overview of pathologic and clinical characteristics in general, a description of the gross and histologic features along with their clinical features, and data on pathogenetic mechanisms. Filled with tables to clarify major points, case histories to provide clinical correlates, and Board-type chapter review questions with answers and explanations, this text will be a valuable addition to all individual and reference libraries. Key Benefits: Almost 600 full color illustrations. Case histories, keyed to images, provide clinical correlation with pathology. Over 90 tables summarizing key points: useful for quick reference and exam preparation. End-of-chapter Board-type questions, with answers and explanations, for self-assessment and exam preparation.

Author : H. Lassmann
Publisher : Springer Science & Business Media
Page : 234 pages
File Size : 34,8 MB
Release : 2012-12-06
Category : Medical
ISBN : 3642455581

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For several decades the unsolved etiogenetic and therapeutic problems of multiple sclerosis have offered the strongest challenge to research in neu rology. The hope of decisive theoretical and practical progress increased when an experimental model presenting far-reaching conformity of structural and pathogenetic features was developed, namely chronic re lapsing experimental allergic encephalomyelitis (CREAE). During the past years, Dr. Lassmann has contributed substantially to the adaptation of this model with the aim of comprehensive evaluation, thoroughly fol lowing up his own ideas in numerous studies of individual aspects. The new possibility of continuous and detailed investigation of the clinical, morphological and immunological characteristics of temporal phase sequence of autoimmune demyelination has led to many new findings, corrections offormer hypotheses, and, from correlated studies of human multiple sclerosis, a series of important data concerning, for example, early manifestations of demyelination, the range of so-called acute mul tiple sclerosis and the incidence of remyelination. Moreover, Dr. Lass mann has analysed several special problems which became definable in the course of his own studies or in collaboration with other groups, in cluding the initial distribution of demyelinated foci, the cerebrospinal fluid phenomena and immunological findings in the nervous tissue. The results of these separate studies also led to a deeper understanding of demyelinating processes. This monograph integrates these studies and summarizes their re sults.

Author : Peter S. Spencer
Publisher :
Page : 958 pages
File Size : 40,8 MB
Release : 1980
Category : Medical
ISBN :

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Two decades have passed since publication of the first edition of Experimental and Clinical Neurotoxicology pioneered the development of this discipline. Since then no other book has approached the breadth, scholarship, and balance of that landmark volume. For this long-awaited second edition, the original editors have been joined by Albert Ludolf, who brings expertise in biological neurotoxicology, and together with their distinguished contributors they have completely rewritten and reorganized the text.The scientific and clinical foundation is laid in three comprehensive introductory chapters. An overview of the biological basis of neurotoxicity provides the goundwork for discussing the scope of human and veterinary neurotoxic disease.The bulk of the text is devoted to an alphabetical treatment of chemicals with neurotoxic potential. This consists of tightly written overviews of the properties, actions, and mechanisms of all manner of substances, whether natural or synthetic. The neurotoxic side effects of experimental agents and of therapeutic as well as abused drugs are covered extensively. Environmental pollutants, workplace contaminants, personal-use products, food additives, and agents harbored by plants, animals, and humans for use against their respective enemies are discussed. Each substance is rated on a three-point scale for the weight of evidence indicating a specific neurotoxic effect in humans, animals, or laboratory models. These effects are summarized and cross-referenced in a series of appendices and an extensive index.In summary, the second edition establishes neurotoxicology as a scientific discipline that melds neurobiology, toxicology, and neurology. From this unique vantage point, the book examines in encyclopedic manner several hundred chemicals with the capacity to induce neurological illness in humans and animals. Indispensable for the experimental neuroscientist and toxicologist, as well as for practitioners of human and animal medicine, the book also provides an authoritative, critical, and pithy reference work for specialists in public health and the legal profession.

Author : Arthur Weil
Publisher : Elsevier
Page : 373 pages
File Size : 47,58 MB
Release : 2013-10-22
Category : Medical
ISBN : 1483225968

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Textbook of Neuropathology, Second Edition covers some of the significant advances in understanding the theoretical and experimental aspects of neuropathology. Neuropathology is the study of the nervous tissue in disease and the determination of deviations of its structures from the normal. This edition is composed of 13 chapters, and begins with the description of the chemical changes occurring in the cell through autolysis and fixation. The subsequent chapters are devoted to studies on better understanding of the vitamin deficiencies, the discovery of the sulfonamides and their contribution to the therapy of meningitis, and the different forms of shock treatment applied to selected cases of neurosis and psychosis. The remaining chapters explore the contribution of neuropathological investigation in various medical conditions, including anemic softening, arteriosclerosis, inflammation, infections, intoxications, injuries, degenerative diseases, tumors, and congenital malformations. This book will be of use to neuropathologists and workers and researchers in the allied fields.