Author : Thomas Marshall Snyder
Publisher :
Page : 278 pages
File Size : 13,98 MB
Release : 2007
Category : Biochemical templates
ISBN : 9780549278948
First, we describe a strategy for performing ordered multistep synthesis in a single solution. This system makes use of temperature-sensitive variations in DNA secondary structure to orchestrate an ordered multistep synthesis of a triolefin and a tripeptide in a single solution. This methodology provides a faster, higher-yielding route to multistep DNA-templated products and represents a mode of controlling chemical reactivity that is not accessible in traditional flask-based reaction formats.