[PDF] Epigenetics Book eBook

Author : Renato Paro
Publisher : Springer Nature
Page : 215 pages
File Size : 14,74 MB
Release : 2021-03-23
Category : Science
ISBN : 3030686701

GET BOOK

This open access textbook leads the reader from basic concepts of chromatin structure and function and RNA mechanisms to the understanding of epigenetics, imprinting, regeneration and reprogramming. The textbook treats epigenetic phenomena in animals, as well as plants. Written by four internationally known experts and senior lecturers in this field, it provides a valuable tool for Master- and PhD- students who need to comprehend the principles of epigenetics, or wish to gain a deeper knowledge in this field. After reading this book, the student will: Have an understanding of the basic toolbox of epigenetic regulation Know how genetic and epigenetic information layers are interconnected Be able to explain complex epigenetic phenomena by understanding the structures and principles of the underlying molecular mechanisms Understand how misregulated epigenetic mechanisms can lead to disease

Author : Trygve O Tollefsbol
Publisher : Academic Press
Page : 684 pages
File Size : 39,40 MB
Release : 2017-07-10
Category : Science
ISBN : 0128054778

GET BOOK

Handbook of Epigenetics: The New Molecular and Medical Genetics, Second Edition, provides a comprehensive analysis of epigenetics, from basic biology, to clinical application. Epigenetics is considered by many to be the new genetics in that many biological phenomena are controlled, not through gene mutations, but rather through reversible and heritable epigenetic processes. These epigenetic processes range from DNA methylation to prions. The biological processes impacted by epigenetics are vast and encompass effects in lower organisms and humans that include tissue and organ regeneration, X-chromosome inactivation, stem cell differentiation, genomic imprinting, and aging. The first edition of this important work received excellent reviews; the second edition continues its comprehensive coverage adding more current research and new topics based on customer and reader reviews, including new discoveries, approved therapeutics, and clinical trials. From molecular mechanisms and epigenetic technology, to discoveries in human disease and clinical epigenetics, the nature and applications of the science is presented for those with interests ranging from the fundamental basis of epigenetics, to therapeutic interventions for epigenetic-based disorders. Timely and comprehensive collection of fully up-to-date reviews on epigenetics that are organized into one volume and written by leading figures in the field Covers the latest advances in many different areas of epigenetics, ranging from basic aspects, to technologies, to clinical medicine Written at a verbal and technical level that can be understood by scientists and college students Updated to include new epigenetic discoveries, newly approved therapeutics, and clinical trials

Author : Nessa Carey
Publisher : Columbia University Press
Page : 353 pages
File Size : 25,99 MB
Release : 2012-03-06
Category : Science
ISBN : 0231530714

GET BOOK

Epigenetics can potentially revolutionize our understanding of the structure and behavior of biological life on Earth. It explains why mapping an organism's genetic code is not enough to determine how it develops or acts and shows how nurture combines with nature to engineer biological diversity. Surveying the twenty-year history of the field while also highlighting its latest findings and innovations, this volume provides a readily understandable introduction to the foundations of epigenetics. Nessa Carey, a leading epigenetics researcher, connects the field's arguments to such diverse phenomena as how ants and queen bees control their colonies; why tortoiseshell cats are always female; why some plants need cold weather before they can flower; and how our bodies age and develop disease. Reaching beyond biology, epigenetics now informs work on drug addiction, the long-term effects of famine, and the physical and psychological consequences of childhood trauma. Carey concludes with a discussion of the future directions for this research and its ability to improve human health and well-being.

Author : C. David Allis
Publisher : CSHL Press
Page : 503 pages
File Size : 24,95 MB
Release : 2007
Category : Epigenesis, Genetic
ISBN : 0879697245

GET BOOK

The regulation of gene expression in many biological processes involves epigenetic mechanisms. In this new volume, 24 chapters written by experts in the field discuss epigenetic effects from many perspectives. There are chapters on the basic molecular mechanisms underpinning epigenetic regulation, discussion of cellular processes that rely on this kind of regulation, and surveys of organisms in which it has been most studied. Thus, there are chapters on histone and DNA methylation, siRNAs and gene silencing; X-chromosome inactivation, dosage compensation and imprinting; and discussion of epigenetics in microbes, plants, insects, and mammals. The last part of the book looks at how epigenetic mechanisms act in cell division and differentiation, and how errors in these pathways contribute to cancer and other human diseases. Also discussed are consequences of epigenetics in attempts to clone animals. This book is a major resource for those working in the field, as well as being a suitable text for advanced undergraduate and graduate courses on gene regulation.

Author : Cath Ennis
Publisher : Icon Books Ltd
Page : 285 pages
File Size : 44,44 MB
Release : 2017-02-02
Category : Science
ISBN : 1848319037

GET BOOK

Epigenetics is the most exciting field in biology today, developing our understanding of how and why we inherit certain traits, develop diseases and age, and evolve as a species. This non-fiction comic book introduces us to genetics, cell biology and the fascinating science of epigenetics, which is rapidly filling in the gaps in our knowledge, allowing us to make huge advances in medicine. We'll look at what identical twins can teach us about the epigenetic effects of our environment and experiences, why certain genes are 'switched on' or off at various stages of embryonic development, and how scientists have reversed the specialization of cells to clone frogs from a single gut cell. In Introducing Epigenetics, Cath Ennis and Oliver Pugh pull apart the double helix, examining how the epigenetic building blocks and messengers that interpret and edit our genes help to make us, well, us.

Author : Trygve Tollefsbol
Publisher : Academic Press
Page : 944 pages
File Size : 15,80 MB
Release : 2016-06-21
Category : Science
ISBN : 0128032405

GET BOOK

Medical Epigenetics provides a comprehensive analysis of the importance of epigenetics to health management. The purpose of this book is to fill a current need for a comprehensive volume on the medical aspects of epigenetics with a focus on human systems, epigenetic diseases that affect these systems and modes of treating epigenetic-based disorders and diseases. The intent of this book is to provide a stand-alone comprehensive volume that will cover all human systems relevant to epigenetic maladies and all major aspects of medical epigenetics. The overall goal is to provide the leading book on medical epigenetics that will be useful not only to physicians, nurses, medical students and many others directly involved with health care, but also investigators in life sciences, biotech companies, graduate students and many others who are interested in more applied aspects of epigenetics. Research in the area of translational epigenetics is a cornerstone of this volume. Critical reviews dedicated to the burgeoning role of epigenetics in medical practice Coverage of emerging topics including twin epigenetics as well as epigenetics of gastrointestinal disease, muscle disorders, endocrine disorders, ocular medicine, pediatric diseases, sports medicine, noncoding RNA therapeutics, pain management and regenerative medicine Encompasses a disease-oriented perspective of medical epigenetics as well as diagnostic and prognostic epigenetic approaches to applied medicine

Author : Michael C. Gerald
Publisher : Union Square + ORM
Page : 1050 pages
File Size : 23,69 MB
Release : 2015-01-06
Category : Science
ISBN : 1454915331

GET BOOK

“This beautifully illustrated book covers four billion years of biology history . . . appealing for readers with little to no background in science.” —Library Journal From the emergence of life, to Leewenhoeks microscopic world, to GMO crops, The Biology Book presents 250 landmarks in the most widely studied scientific field. Brief, engaging, and colorfully illustrated synopses introduce readers to every major subdiscipline, including cell theory, genetics, evolution, physiology, thermodynamics, molecular biology, and ecology. With information on such varied topics as paleontology, pheromones, nature vs. nurture, DNA fingerprinting, bioenergetics, and so much more, this lively collection will engage everyone who studies and appreciates the life sciences.

Author : Leonie Ringrose
Publisher : Academic Press
Page : 287 pages
File Size : 29,17 MB
Release : 2017-04-25
Category : Science
ISBN : 0128030763

GET BOOK

Epigenetics and Systems Biology highlights the need for collaboration between experiments and theoretical modeling that is required for successful application of systems biology in epigenetics studies. This book breaks down the obstacles which exist between systems biology and epigenetics researchers due to information barriers and segmented research, giving real-life examples of successful combinations of systems biology and epigenetics experiments. Each section covers one type of modeling and one set of epigenetic questions on which said models have been successfully applied. In addition, the book highlights how modeling and systems biology relate to studies of RNA, DNA, and genome instability, mechanisms of DNA damage signaling and repair, and the effect of the environment on genome stability. Presents original research in a wider perspective to reveal potential for synergies between the two fields of study Provides the latest experiments in primary literature for the modeling audience Includes chapters written by experts in systems biology and epigenetics who have vast experience studying clinical applications

Author :
Publisher : Academic Press
Page : 541 pages
File Size : 49,96 MB
Release : 2019-05-24
Category : Science
ISBN : 0128148802

GET BOOK

Epigenetics and Regeneration compiles the first foundational reference on epigenetic mechanisms governing tissue development, repair, homeostasis, and regeneration, as well as pathways to employ these mechanisms in clinical practice and translational science. In this book, life science researchers, clinicians, and students will discover an interdisciplinary resource bringing together common themes in the field, background overviews, research methods, recent advances, and opportunities for drug discovery. Throughout this volume, special attention is paid to pre-clinical and first clinical studies aimed at increasing the regenerative potential of damaged tissues by epigenetic drugs, as well as innovative, discipline spanning strategies to enhance cell reprogramming. As an all-inclusive, evidence-based volume, Epigenetics and Regeneration will stimulate discussion and boost new research in this fascinating and impactful area of translational epigenetics. Provides a foundational overview of epigenetics in regenerative medicine Examines epigenetic components of tissue regeneration for a variety of organ systems and tissue types, as well as current attempts to employ these mechanisms in clinical practice Offers researchers, students, clinicians, and pharmacologists the tools they need to enhance tissue development, repair, homeostasis, and regeneration and explore new epigenetic therapeutic pathways Features chapter contributions from leading international researchers and clinicians in the fields of epigenetics and regenerative medicine

Author : David Shenk
Publisher : Anchor
Page : 401 pages
File Size : 47,59 MB
Release : 2011-03-08
Category : Psychology
ISBN : 0307387305

GET BOOK

"Fresh insights into the nature of exceptional peformance…. A deeply interesting and important book” (New York Times Book Review) that offers a revolutionary and life-changing message on the new science of human potential. Is true greatness obtainable from everyday means and everyday genes? Conventional wisdom says no, that a lucky few are simply born with certain gifts. Now you can forget everything you think you know about genes, talent, and intelligence, and take a look at the amazing new evidence. Here, interweaving cutting-edge research from numerous scientific fields, David Shenk offers a new view of human potential, giving readers more of a sense of ownership over their accomplishments, and freeing parents from the bonds of genetic determinism. As Shenk points out, our genes are not a “blueprint” that dictate individual destinies. Rather we are all the product of interplay between genes and outside stimuli—a dynamic that we can influence. It is a revolutionary and life-changing message.