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This book discusses the maximal power and capacity of the three major biochemical pathways - aerobic (oxygen consumption), anaerobic lactic (muscle lactate accumulation in absence of oxygen consumption), and anaerobic alactic (phosphocreatine hydrolysis) metabolism - as well as the factors that limit them. It also discusses the metabolic and cardio-pulmonary mechanisms of the dynamic response to exercise. The way and extent to which the power and capacity of the three major energy metabolisms are affected under a number of different conditions, such as training, hypoxia and microgravity, are also described.
Muscle and Exercise Physiology is a comprehensive reference covering muscle and exercise physiology, from basic science to advanced knowledge, including muscle power generating capabilities, muscle energetics, fatigue, aging and the cardio-respiratory system in exercise performance. Topics presented include the clinical importance of body responses to physical exercise, including its impact on oxygen species production, body immune system, lipid and carbohydrate metabolism, cardiac energetics and its functional reserves, and the health-related effects of physical activity and inactivity. Novel topics like critical power, ROS and muscle, and heart muscle physiology are explored. This book is ideal for researchers and scientists interested in muscle and exercise physiology, as well as students in the biological sciences, including medicine, human movements and sport sciences. Contains basic and state-of-the-art knowledge on the most important issues of muscle and exercise physiology, including muscle and body adaptation to physical training, the impact of aging and physical activity/inactivity Provides both the basic and advanced knowledge required to understand mechanisms that limit physical capacity in both untrained people and top class athletes Covers advanced content on muscle power generating capabilities, muscle energetics, fatigue and aging
Howard G. Knuttgen of Biology, Boston University, 2 Cummington Department Street, Boston, 02215 Massachusetts, USA The relationship of the formation of lactate acid to skeletal muscle energy release in exercising humans was first explored by A. V. Hill and co-workers (2l, 22). The term "oxygen debt" was suggested by them to describe the excess oxygen consumption of recovery which they felt was closely related. A combination of their work and the earlier work of Krogh and Lindhard (35) re sulted at that time in the belief that a certain amount of energy release during the transition from rest to exercise was provided by a non-aerobic source, glycolysis. The resulting accumulation of lactic acid (as lactate) in the body required an extra con sumption during recovery for its oxidative removal. Jervell (24) subsequently showed that, in exercise, the greatest accumulation in blood took place during the first few minutes. He felt that the blood lactate increase was due to a shortage of oxygen during the transition period. The observation was also made for the first time that the increased level of lac tate due to exercise could be made to fall faster if mild exercise was employed by the subjects in place of sedentary recovery. The work of Margaria, Edwards and Dill (40) appeared in 1933. They observed that exercise (treadmill running) could be carried on at low levels without significant changes in resting levels of blood lactate.
With a legacy spanning more than 40 years, Exercise Physiology: Nutrition, Energy, and Human Performance has helped nearly half a million students and exercise science practitioners build a solid foundation in the scientific principles underlying modern exercise physiology. This widely praised, trendsetting text presents a research-centric approach in a vibrant, engaging design to make complex topics accessible and deliver a comprehensive understanding of how nutrition, energy transfer, and exercise training affect human performance. The extensively updated 9th Edition reflects the latest advances in the field as well as a rich contextual perspective to ensure readiness for today’s clinical challenges.
Abstract: This third edition of the book integrates basic concepts and relevant scientific information to provide the foundation for understanding nutrition, energy transfer, and exercise and training. Designed for both the beginning and advanced student, the subjects covered include energy for physical activity, systems of energy delivery and utilization, enhancement of energy capacity, work performance and environmental stress, body composition, energy balance, and weight control, and the metric system and SI units.
How do our muscles produce energy for exercise and what are the underlying biochemical principles involved? These are questions that students need to be able to answer when studying for a number of sport related degrees. This can prove to be a difficult task for those with a relatively limited scientific background. Biochemistry for Sport and Exercise Metabolism addresses this problem by placing the primary emphasis on sport, and describing the relevant biochemistry within this context. The book opens with some basic information on the subject, including an overview of energy metabolism, some key aspects of skeletal muscle structure and function, and some simple biochemical concepts. It continues by looking at the three macromolecules which provide energy and structure to skeletal muscle - carbohydrates, lipids, and protein. The last section moves beyond biochemistry to examine key aspects of metabolism - the regulation of energy production and storage. Beginning with a chapter on basic principles of regulation of metabolism it continues by exploring how metabolism is influenced during high-intensity, prolonged, and intermittent exercise by intensity, duration, and nutrition. Key Features: A clearly written, well presented introduction to the biochemistry of muscle metabolism. Focuses on sport to describe the relevant biochemistry within this context. In full colour throughout, it includes numerous illustrations, together with learning objectives and key points to reinforce learning. Biochemistry for Sport and Exercise Metabolism will prove invaluable to students across a range of sport-related courses, who need to get to grips with how exercise mode, intensity, duration, training status and nutritional status can all affect the regulation of energy producing pathways and, more important, apply this understanding to develop training and nutrition programmes to maximise athletic performance.
This book describes the evolution of ideas relating to the mechanism of muscular contraction since the discovery of sliding filaments in 1954. An amazing variety of experimental techniques have been employed to investigate the mechanism of muscular contraction and relaxation. Some background of these various techniques is presented in order to gain a fuller appreciation of their strengths and weaknesses. Controversies in the muscle field are discussed along with some missed opportunities and false trails. The pathway to ATP and the high energy phosphate bond will be discussed, as well as the discovery of myosin, contraction coupling and the emergence of cell and molecular biology in the muscle field. Numerous figures from original papers are also included for readers to see the data that led to important conclusions. This book is published on behalf of the American Physiological Society by Springer. Access to APS books published with Springer is free to APS members.