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Evidence Synthesis for Decision Making in Healthcare

Author : Nicky J. Welton
Publisher : John Wiley & Sons
Page : 296 pages
File Size : 32,83 MB
Release : 2012-04-12
Category : Mathematics
ISBN : 111830540X

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In the evaluation of healthcare, rigorous methods of quantitative assessment are necessary to establish interventions that are both effective and cost-effective. Usually a single study will not fully address these issues and it is desirable to synthesize evidence from multiple sources. This book aims to provide a practical guide to evidence synthesis for the purpose of decision making, starting with a simple single parameter model, where all studies estimate the same quantity (pairwise meta-analysis) and progressing to more complex multi-parameter structures (including meta-regression, mixed treatment comparisons, Markov models of disease progression, and epidemiology models). A comprehensive, coherent framework is adopted and estimated using Bayesian methods. Key features: A coherent approach to evidence synthesis from multiple sources. Focus is given to Bayesian methods for evidence synthesis that can be integrated within cost-effectiveness analyses in a probabilistic framework using Markov Chain Monte Carlo simulation. Provides methods to statistically combine evidence from a range of evidence structures. Emphasizes the importance of model critique and checking for evidence consistency. Presents numerous worked examples, exercises and solutions drawn from a variety of medical disciplines throughout the book. WinBUGS code is provided for all examples. Evidence Synthesis for Decision Making in Healthcare is intended for health economists, decision modelers, statisticians and others involved in evidence synthesis, health technology assessment, and economic evaluation of health technologies.

A Resource for Developing an Evidence Synthesis Report for Policy-making

Author : Leena Eklund Karlsson
Publisher : World Health Organization
Page : 73 pages
File Size : 32,71 MB
Release : 2017-09-27
Category : Law
ISBN : 928905266X

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Evidence syntheses use multidisciplinary and intersectoral sources of evidence to support policy-making. The Health Evidence Network (HEN) has supported and strengthened the use of evidence in health policy-making in the WHO European Region since 2003. The HEN synthesis report series responds to public health questions by summarizing the best available global and local findings from peer-reviewed and grey literature as well as policy options and proposes general directions strategies and actions for consideration. This resource has been developed to outline key approaches methods and considerations for a HEN evidence synthesis to support the systematic and routine use of the best available evidence for decision-making relevant to the needs of public health decision-makers. It proposes approaches that hold both scientific rigour and practical applicability for individuals and institutions that perform commission review and/or publish evidence syntheses.

Evidence on Mechanisms and Tools for Use of Health Information for Decision-making

Author : Victoria Blessing
Publisher : World Health Organization
Page : 67 pages
File Size : 15,45 MB
Release : 2017-12-06
Category : Law
ISBN : 9289052759

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The World Health Assembly in 2005 urged Member States to establish or strengthen knowledge transfer mechanisms to support evidence-informed health policies and health care delivery. The European Health Information Initiative was set up to strengthen the use of evidence information and research for policy-making in the WHO European Region. While good-quality health information is a key component for decision-making it needs to be packaged and communicated in an effective way to policy-makers the end-users. This report describes tools and mechanisms that can help to increase the use of health information in policy development. Packaging tools include synthesis methods such as policy briefs and visualization methods. Application tools include surveillance data and modelling/simulation to explore the behaviour and performance of processes and interventions. Dissemination and communication tools include health information-sharing platforms newsletters and person-to-person communications. Finally linkage and exchange tools such as knowledge networks facilitate the dissemination and refining of health information thus increasing the chance of its translation into policy.

Synthesising Qualitative And Quantitative Health Evidence: A Guide To Methods

Author : Pope, Catherine
Publisher : McGraw-Hill Education (UK)
Page : 222 pages
File Size : 19,34 MB
Release : 2007-07-01
Category : Medical
ISBN : 033521956X

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Provides a comprehensive overview of range of approaches and methods available for synthesising qualitative and quantitative evidence and an explanation of why this is important. This book looks at different types of review and examining place of synthesis in reviews for policy and management decision making.

Finding What Works in Health Care

Author : Institute of Medicine
Publisher : National Academies Press
Page : 267 pages
File Size : 34,78 MB
Release : 2011-07-20
Category : Medical
ISBN : 0309164257

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Healthcare decision makers in search of reliable information that compares health interventions increasingly turn to systematic reviews for the best summary of the evidence. Systematic reviews identify, select, assess, and synthesize the findings of similar but separate studies, and can help clarify what is known and not known about the potential benefits and harms of drugs, devices, and other healthcare services. Systematic reviews can be helpful for clinicians who want to integrate research findings into their daily practices, for patients to make well-informed choices about their own care, for professional medical societies and other organizations that develop clinical practice guidelines. Too often systematic reviews are of uncertain or poor quality. There are no universally accepted standards for developing systematic reviews leading to variability in how conflicts of interest and biases are handled, how evidence is appraised, and the overall scientific rigor of the process. In Finding What Works in Health Care the Institute of Medicine (IOM) recommends 21 standards for developing high-quality systematic reviews of comparative effectiveness research. The standards address the entire systematic review process from the initial steps of formulating the topic and building the review team to producing a detailed final report that synthesizes what the evidence shows and where knowledge gaps remain. Finding What Works in Health Care also proposes a framework for improving the quality of the science underpinning systematic reviews. This book will serve as a vital resource for both sponsors and producers of systematic reviews of comparative effectiveness research.

Evidence on Mechanisms and Tools for Use of Health Information for Decision-making

Author : Victoria Blessing
Publisher :
Page : 51 pages
File Size : 19,78 MB
Release : 2017
Category : Medical informatics
ISBN : 9789240698796

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The World Health Assembly in 2005 urged Member States to establish or strengthen knowledge transfer mechanisms to support evidence-informed health policies and health care delivery. The European Health Information Initiative was set up to strengthen the use of evidence, information and research for policy-making in the WHO European Region. While good-quality health information is a key component for decision-making, it needs to be packaged and communicated in an effective way to policy-makers, the end-users. This report describes tools and mechanisms that can help to increase the use of health information in policy development. Packaging tools include synthesis methods, such as policy briefs, and visualization methods. Application tools include surveillance data and modelling/simulation to explore the behaviour and performance of processes and interventions. Dissemination and communication tools include health information-sharing platforms, newsletters and person-to-person communications. Finally, linkage and exchange tools such as knowledge networks facilitate the dissemination and refining of health information, thus increasing the chance of its translation into policy.

Evidence-Based Review in Policy and Practice, an Issue of Nursing Clinics

Author : Alan Pearson
Publisher : Clinics: Nursing
Page : 0 pages
File Size : 22,37 MB
Release : 2014-12-02
Category : Medical
ISBN : 9780323326629

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Evidence synthesis is the evaluation or analysis of research evidence and opinion on a specific topic to aid in decision-making in health care. Although the science of evidence synthesis has developed most rapidly in relation to the meta-analysis of numerical data linked to theories of cause and effect, the further development of theoretical understandings and propositions of the nature of evidence, its role in health care delivery, and the facilitation of improved global health have increased rapidly since 2000. The articles appearing in this issue examine the role of evidence synthesis in nursing and health care and are written by expert translational scientists from across the world. Three introductory articles overview evidence synthesis and its role in evidence-based health care; methods, issues, and trends in the systematic review of health care evidence; and the development of a robust evidence base for nursing. Subsequent articles explore the impact of systematic reviews on policy and practice in a variety of settings, including perioperative care, pediatrics, rehabilitation and long-term/continuing care, mental health, and public health. The final articles discuss the impact of evidence on health policy and practice and the complexities of translating evidence into policy and practice. These articles show the importance of synthesizing evidence and translating policy and practice into action in our quest to improve health care and health outcomes.