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Coronavirus Disease-19 (COVID-19): Different Models and Treatment Strategies

Author : Kamal Niaz
Publisher : Bentham Science Publishers
Page : 371 pages
File Size : 12,31 MB
Release : 2021-11-01
Category : Medical
ISBN : 1681089084

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In this book volume-2 proposal has been classified into Part IV: Models for SARS-CoV-2 and Part V: Treatment Strategies for SARS-CoV-2. With the emergence of new coronavirus variants, epidemiology, different host tropism permits a thorough analysis of their evolution and acquired adaptability to their host which need different animal models and treatment approaches. No studies are complete without animal models closely related to human physiology to replicate the disease and observe the pathology conditions as in human cases. Such animal models play a vital role in virus pathogenesis and prepare a therapeutic immune response. Here describe bio-engineered transgenic mouse model inserting with specific genes, or CRISPR-Case9 gene-editing tool has been used previously for SARS-CoV and MERS-CoV. The chapter will deal with culture techniques or cell lines for COVID-19—also histopathology of COVID-19, essential proteins that up or down-regulate SARS-CoV-2. The last chapter of this part will describe other diseases having similar signs and symptoms and their differentiation. There is no specific treatment available to date, just symptomatic therapy. However, scientists will elucidate effective antiviral drugs in clinical trials, phytochemicals, photomedicine such as ultraviolet A & B, homemade remedies, blood plasma transfusion, stem cell therapy, and computational approaches in vivo and in vitro trials. This book will appear as a baseline for academicians, scientists, and health professionals as still, research is going to overcome this outbreak of COVID-19, the novelty of best animal models, and find an effective treatment. However, just a single book proposal like this wouldn't have flourished without enthusiasm and determined publishers' and investigators' strength to take time from their busy schedule and subsidize on time. We thank the whole investigators who contributed, directly and indirectly, to bring it to reality.

Handbook of Research on Pathophysiology and Strategies for the Management of COVID-19

Author : El Hiba, Omar
Publisher : IGI Global
Page : 352 pages
File Size : 16,30 MB
Release : 2021-08-13
Category : Medical
ISBN : 1799882268

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According to the World Health Organization (WHO), coronavirus disease (COVID-19) is an infectious disease caused by a newly discovered coronavirus (SARS-Cov2), which may cause mild to moderate respiratory complications in most infected people. Older people and those with chronic and/or acute illnesses may present serious complications. Underlying mechanisms of the cellular responses to the virus are not fully revealed; therefore, understanding the pathophysiology of COVID-19 is crucial to provide efficient data to define the appropriate and effective therapeutic strategies to cure and prevent COVID-19-associated complications. The Handbook of Research on Pathophysiology and Strategies for the Management of COVID-19 summarizes and assembles the published data on COVID-19 and provides an answer to the reader for the mystery of SARS-Cov2’s impact on human health through a deep analysis of the current data available in the literature. This book addresses the epidemiology and infectious patterns of the disease and the recent pathophysiological mechanisms of the disease and relationships to the medical history of the patient. Covering topics from the tie between COVID-19 and respiratory disease to vaccination information, this comprehensive reference source is ideal for clinicians, health professionals, pathologists, virologists, researchers, academicians, and medical and PhD students.

The COVID-19 Pandemic

Author : Hanadi Talal Ahmedah
Publisher : CRC Press
Page : 658 pages
File Size : 10,76 MB
Release : 2022-07-07
Category : Health & Fitness
ISBN : 1000577260

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This timely volume is a comprehensive review of the evolution, diagnosis, prevention, control, and treatment strategies (both modern as well as complementary and alternative) being used against COVID-19. With chapters written by experts in diverse medical fields from around the world, the volume presents authentic and easily understood information on this novel and often deadly virus. The book is organized in sections that cover pathology, epidemiology, and diagnosis; prevention strategies; and treatment. The book first covers the morphology, pathogenesis, genome organization and replication of coronavirus (COVID-19) and then goes on to address epidemiology and pathogenesis, the psychological effects, and detection assays and techniques. Chapters on prevention strategies discuss social distancing and quarantine, face masks and hand sanitizers, lockdown strategies, and vaccines. The authors also cover diverse treatment strategies, including using medicinal plants, natural products, and traditional Chinese medicines as well as nanomedicines.

Diagnosis and Analysis of COVID-19 using Artificial Intelligence and Machine Learning-Based Techniques

Author : Mohammad Sufian Badar
Publisher : Elsevier
Page : 428 pages
File Size : 38,69 MB
Release : 2024-07-25
Category : Science
ISBN : 0323953735

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Diagnosis and Analysis of COVID-19 using Artificial Intelligence and Machine Learning-Based Techniques offers new insights and demonstrates how machine learning (ML), artificial intelligence (AI), and (Internet of Things (IoT) can be used to diagnose and fight COVID-19 infection. Sections also discuss the challenges we face in using these technologies. Chapters cover pathogenesis, transmission, diagnosis, and treatment strategies for COVID-19, Artificial Intelligence and Machine Learning, and Blockchain /IoT Blockchain technology, examining how AI can be applied as a tool for detection and containment of the spread of COVID-19, and on the socioeconomic and educational post-pandemic impacts of the disease. This is a multidisciplinary resource for those engaged in researching COVID-19 and how emerging technologies are being used as tools for detection, transmission and treatment strategies. Describes the molecular basis of pathogenesis, epidemiology, transmission mechanism, diagnostic approaches, and the mutational landscape of SARS-CoV-2 Provides insights into post COVID-19 symptoms and consequences Demonstrates how machine learning, AI, and IoT is used to diagnose and fight COVID-19 infection Examines the use of Blockchain technology/IoT and interpretation and validation of data obtained from artificial intelligence

Interaction of Coronavirus Disease 2019 with other Infectious and Systemic Diseases

Author : M. Tabish Qidwai
Publisher : CRC Press
Page : 210 pages
File Size : 22,22 MB
Release : 2023-10-31
Category : Science
ISBN : 1000958515

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The book "Interaction of Coronavirus Disease 2019 with other Infectious and Systemic Diseases" elaborates on the pathogenesis, co-infection, and association of COVID-19 with other Infectious and Systemic Diseases. Moreover, this book explains pharmacological interventions, and therapeutic targets in COVID19. All chapters cover the different aspects of COVID-19. This book gives first-hand information on the co-infection, post-COVID effects, nanomedicine, and pharmacogenomics in COVID-19. The book offers comprehensive coverage of the most essential topics, including: Recent developments in COVID-19 pathogenesis and treatment Association of COVID-19 with Infectious diseases and Systemic Diseases COVID-19 and Co-infection Post-COVID and long-term COVID problems Nanomedicine and pharmacogenomics in COVID-19 While other books may touch on COVID-19 pathophysiology and treatment strategies. Unique aspect of this book is that it covers post COVID effects, and Interaction of Coronavirus Disease 2019 with other Infectious and Systemic Diseases.

Computational Intelligence Methods in COVID-19: Surveillance, Prevention, Prediction and Diagnosis

Author : Khalid Raza
Publisher : Springer Nature
Page : 436 pages
File Size : 27,97 MB
Release : 2020-10-16
Category : Technology & Engineering
ISBN : 9811585342

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The novel coronavirus disease 2019 (COVID-19) pandemic has posed a major threat to human life and health. This book is beneficial for interdisciplinary students, researchers, and professionals to understand COVID-19 and how computational intelligence can be used for the purpose of surveillance, control, prevention, prediction, diagnosis, and potential treatment of the disease. The book contains different aspects of COVID-19 that includes fundamental knowledge, epidemic forecast models, surveillance and tracking systems, IoT- and IoMT-based integrated systems for COVID-19, social network analysis systems for COVID-19, radiological images (CT, X-ray) based diagnosis system, and computational intelligence and in silico drug design and drug repurposing methods against COVID-19 patients. The contributing authors of this volume are experts in their fields and they are from various reputed universities and institutions across the world. This volume is a valuable and comprehensive resource for computer and data scientists, epidemiologists, radiologists, doctors, clinicians, pharmaceutical professionals, along with graduate and research students of interdisciplinary and multidisciplinary sciences.

Delineating Health and Health System: Mechanistic Insights into Covid 19 Complications

Author : R. C. Sobti
Publisher : Springer Nature
Page : 496 pages
File Size : 47,6 MB
Release : 2021-11-30
Category : Medical
ISBN : 9811651051

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This book discusses the organ-specific systemic manifestations of COVID-19. The initial chapters of the book review the origin and evolution of the coronaviruses, followed by pathogenesis and immune response during COVID-19 infection. The book also provides insight into the role of angiotensin-converting enzyme 2 in the onset of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pathogenesis. It summarizes the neurological aspects of SARS-CoV2, including transmission pathways, mechanisms of invasion into the nervous system, and mechanisms of neurological disease. It also delineates the association of severe disease with high blood plasma levels of inflammatory cytokines and inflammatory markers in SARS-CoV-2 infection. Lastly, it discusses the perturbation of gut microbiota by SARS-CoV-2 and uncovers the potential risk of virus infection on reproductive health.

COVID-19 and SARS-CoV-2

Author : Srijan Goswami
Publisher : CRC Press
Page : 264 pages
File Size : 40,38 MB
Release : 2022-07-11
Category : Health & Fitness
ISBN : 1000601498

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Since the end of December 2019, the world has been battling with a global health emergency called COVID-19. This ongoing pandemic has claimed millions of lives worldwide and made a serious impact on global healthcare. The information and facts about the virus and the pandemic are constantly evolving, expanding and are present in a scattered manner. Above all, various rumors and false information are also spreading through word of mouth or social media in relation to the pandemic. In situations like this, it becomes hard for a common person as well as professionals to keep track of the fundamental concepts, ongoing scientific advancements and differentiate between the facts and myths. COVID-19 and SARS-CoV-2: The Science and Clinical Application of Conventional and Complementary Treatments covers the fundamental concepts regarding SARS-CoV-2 and COVID–19 as well as common concerns and issues ensuring optimal understanding of the latest basic science and clinical content. The comparative coverage of Conventional Medical Science with Complementary and Alternative Systems of Medicine in relation to the ongoing pandemic makes this book unique compared to other books available on COVID-19. Written in textbook format and in semi-technical style, it provides basic to advanced concepts and multidimensional clinical perspectives keeping in mind the diverse needs of academicians, researchers, students and common people. Key Features: Contains simple, lucid and concise presentation of contents Emphasizes core knowledge and concepts Presents evidence based and up to date information from a multidisciplinary perspective Includes illustrations with good quality diagrams and colored photographs for ease of understanding. COVID-19 and SARS-CoV-2 covers concepts and protocols from holistic perspective relating to core Molecular Biology of SARS-CoV-2, Clinical and Therapeutic Aspects, Multidisciplinary Treatment and Management Strategies like Conventional Pharmacological Treatments, Vaccines, Ayurveda, Homoeopathy, Holistic Nutrition Therapy, Nutraceutical Therapy, Biochemic Medicine, and Issues and Concerns relating to Public Health and Ongoing Advances in Research in relation to COVID-19. Written in semi-technical language easily understandable by readers from all domains, this book provides multidisciplinary perspective, knowledge and understanding regarding COVID-19 in one place, thus bridging the knowledge gap that exists between Conventional Sciences and Complementary and Alternative Medicine Systems.

Demystifying COVID-19: Understanding the Disease, Its Diagnosis and Treatment

Author : Ozgur Karcioglu
Publisher : Bentham Science Publishers
Page : 413 pages
File Size : 39,78 MB
Release : 2021-05-24
Category : Medical
ISBN : 1681087790

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The management of COVID-19 is challenging due to the lack of clear information about the Sars-Cov2 and recommendations for specific treatment regimens. The scale of the pandemic has also exacerbated the situation, with health care systems under stress from the high volume of COVID-19 patients. In Demystifying COVID-19: Understanding the Disease, Its Diagnosis, and Treatment, medical experts explain many aspects about the COVID-19 pandemic, including guidelines to minimize risk of infection, diagnostic methods, treatment, real scenarios in the course of the disease and issues that need attention in specific patient groups. The book equips both general readers and healthcare professionals with key information required to understand COVID-19 and navigate a situation typical to a pandemic. Public health officials who wish to mobilize awareness campaigns for the benefit of the general public can also find value in the comprehensive information presented in this reference.

Modeling, Control and Drug Development for COVID-19 Outbreak Prevention

Author : Ahmad Taher Azar
Publisher : Springer Nature
Page : 1115 pages
File Size : 22,26 MB
Release : 2021-11-01
Category : Computers
ISBN : 303072834X

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This book is well-structured book which consists of 31 full chapters. The book chapters' deal with the recent research problems in the areas of modeling, control and drug development, and it presents various techniques of COVID-19 outbreak prevention modeling. The book also concentrates on computational simulations that may help speed up the development of drugs to counter the novel coronavirus responsible for COVID-19. This is an open access book.