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Author : Chunfang Jin
Publisher :
Page : 136 pages
File Size : 26,4 MB
Release : 2004
Category :
ISBN :
Author : Nicola J. Camp
Publisher : Springer Science & Business Media
Page : 362 pages
File Size : 27,24 MB
Release : 2008-02-03
Category : Medical
ISBN : 1592591760
In Quantitative Trait Loci: Methods and Protocols, a panel of highly experienced statistical geneticists demonstrate in a step-by-step fashion how to successfully analyze quantitative trait data using a variety of methods and software for the detection and fine mapping of quantitative trait loci (QTL). Writing for the nonmathematician, these experts guide the investigator from the design stage of a project onwards, providing detailed explanations of how best to proceed with each specific analysis, to find and use appropriate software, and to interpret results. Worked examples, citations to key papers, and variations in method ease the way to understanding and successful studies. Among the cutting-edge techniques presented are QTDT methods, variance components methods, and the Markov Chain Monte Carlo method for joint linkage and segregation analysis.
Author : Michael Lynch
Publisher : Sinauer Associates Incorporated
Page : 980 pages
File Size : 19,16 MB
Release : 1998-01
Category : Science
ISBN : 9780878934812
Professors Lynch and Walsh bring together the diverse array of theoretical and empirical applications of quantitative genetics in a work that is comprehensive and accessible to anyone with a rudimentary understanding of statistics and genetics.
Author : Joel Ira Weller
Publisher : CABI
Page : 288 pages
File Size : 32,97 MB
Release : 2009
Category : Technology & Engineering
ISBN : 1845937341
Quantitative Trait Loci (QTL) is a topic of major agricultural significance for efficient livestock production. This book covers various statistical methods that have been used or proposed for detection and analysis of QTL and marker-and gene-assisted selection in animal genetics and breeding.
Author : Scott A. Rifkin
Publisher : Humana Press
Page : 331 pages
File Size : 13,91 MB
Release : 2012-05-09
Category : Medical
ISBN : 9781617797866
Over the last two decades advances in genotyping technology, and the development of quantitative genetic analytical techniques have made it possible to dissect complex traits and link quantitative variation in traits to allelic variation on chromosomes or quantitative trait loci (QTLs). In Quantitative Trait Loci (QTLs):Methods and Protocols, expert researchers in the field detail methods and techniques that focus on specific components of the entire process of quantitative train loci experiments. These include methods and techniques for the mapping populations, identifying quantitative trait loci, extending the power of quantitative trait locus analysis, and case studies. Written in the highly successful Methods in Molecular BiologyTM series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory. Thorough and intuitive, Quantitative Trait Loci (QTLs):Methods and Protocols aids scientists in the further study of the links between phenotypic and genotypic variation in fields from medicine to agriculture, from molecular biology to evolution to ecology.
Author : Bruce Walsh
Publisher : Oxford University Press
Page : 1504 pages
File Size : 37,53 MB
Release : 2018-06-21
Category : Science
ISBN : 0192566644
Quantitative traits-be they morphological or physiological characters, aspects of behavior, or genome-level features such as the amount of RNA or protein expression for a specific gene-usually show considerable variation within and among populations. Quantitative genetics, also referred to as the genetics of complex traits, is the study of such characters and is based on mathematical models of evolution in which many genes influence the trait and in which non-genetic factors may also be important. Evolution and Selection of Quantitative Traits presents a holistic treatment of the subject, showing the interplay between theory and data with extensive discussions on statistical issues relating to the estimation of the biologically relevant parameters for these models. Quantitative genetics is viewed as the bridge between complex mathematical models of trait evolution and real-world data, and the authors have clearly framed their treatment as such. This is the second volume in a planned trilogy that summarizes the modern field of quantitative genetics, informed by empirical observations from wide-ranging fields (agriculture, evolution, ecology, and human biology) as well as population genetics, statistical theory, mathematical modeling, genetics, and genomics. Whilst volume 1 (1998) dealt with the genetics of such traits, the main focus of volume 2 is on their evolution, with a special emphasis on detecting selection (ranging from the use of genomic and historical data through to ecological field data) and examining its consequences.
Author : Rongling Wu
Publisher : Springer Science & Business Media
Page : 371 pages
File Size : 32,14 MB
Release : 2007-07-17
Category : Science
ISBN : 038768154X
This book introduces the basic concepts and methods that are useful in the statistical analysis and modeling of the DNA-based marker and phenotypic data that arise in agriculture, forestry, experimental biology, and other fields. It concentrates on the linkage analysis of markers, map construction and quantitative trait locus (QTL) mapping, and assumes a background in regression analysis and maximum likelihood approaches. The strength of this book lies in the construction of general models and algorithms for linkage analysis, as well as in QTL mapping in any kind of crossed pedigrees initiated with inbred lines of crops.
Author : Ariel Darvasi
Publisher :
Page : 224 pages
File Size : 24,69 MB
Release : 1994
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Author : Simon A MacKenzie
Publisher : Academic Press
Page : 306 pages
File Size : 21,57 MB
Release : 2016-07-29
Category : Technology & Engineering
ISBN : 0128016906
Genomics in Aquaculture is a concise, must-have reference that describes current advances within the field of genomics and their applications to aquaculture. Written in an accessible manner for anyone—non-specialists to experts alike—this book provides in-depth coverage of genomics spanning from genome sequencing, to transcriptomics and proteomics. It provides, for ease of learning, examples from key species most relevant to current intensive aquaculture practice. Its coverage of minority species that have a specific biological interest (e.g., Pleuronectiformes) makes this book useful for countries that are developing such species. It is a robust, practical resource that covers foundational, functional, and applied aspects of genomics in aquaculture, presenting the most current information in a field of research that is rapidly growing. Provides the latest scientific methods and technologies to maximize efficiencies for healthy fish production, with summary tables for quick reference Offers an extended glossary of technical and methodological terms to help readers better understand key biological concepts Describes state-of-the-art technologies, such as transcriptomics and epigenomics, currently under development for future perspective of the field Covers minority species that have a specific biological interest (e.g., Pleuronectiformes), making the book useful to countries developing such species
Author : Fengxing Du
Publisher :
Page : 340 pages
File Size : 16,92 MB
Release : 1999
Category :
ISBN :